Results 121 to 130 of about 1,278,587 (252)

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Transcriptional profiling of synovial macrophages using minimally invasive ultrasound-guided synovial biopsies in rheumatoid arthritis [PDF]

, 2018
Objective Currently, there are no reliable biomarkers for predicting therapeutic response in patients with rheumatoid arthritis (RA). The synovium may unlock critical information for determining efficacy as reduction in numbers of sublining synovial ...
Homan, PJ, Mandelin, AM, Buckley, Christopher, Et al., Et, Et al., Shaffer, AM, Buckley, CD   +6 more
core   +1 more source

Immunohistological assessment of the synovial tissue in small joints in rheumatoid arthritis: validation of a minimally invasive ultrasound-guided synovial biopsy procedure

Arthritis Research & Therapy, 2007
The aim of the present study was to perform an immunohistological assessment of the synovial tissue from involved small joints in rheumatoid arthritis (RA) and to explore the reliability of a mini-invasive ultrasound (US)-guided technique of small joint ...
C. Scirè, O. Epis, V. Codullo, F. Humby, P. Morbini, A. Manzo, R. Caporali, C. Pitzalis, C. Montecucco   +8 more
semanticscholar   +1 more source

Peri‐implantitis and systemic inflammation: Current evidence, biological plausibility, and research gaps

Periodontology 2000, EarlyView.
Abstract Background Peri‐implantitis is a biofilm‐associated inflammatory condition characterized by peri‐implant mucosal inflammation and progressive bone loss. The prevalence of peri‐implantitis continues to rise among patients with dental implants. Although peri‐implantitis and periodontitis share similar inflammatory phenotypes, histopathological ...
Yumeng Yan, Jeanie Suvan, Francesco D'Aiuto   +2 more
wiley   +1 more source

Oral health and systemic health outcomes: A call for interdisciplinary action

Periodontology 2000, EarlyView.
Abstract Objectives To make the case, from periodontology and dental public health, for interdisciplinary action on oral and systemic health, and to set out recommendations for practice, policy, education, and research. Materials and Methods A joint working group of the European Federation of Periodontology (EFP) and the European Association of Dental ...
Moritz Kebschull, Ryan T. Demmer, Nigel Pitts, Huda Yusuf, Gitana Rederiene, Nikolaos Donos, Wim Teughels, Raman Bedi, Orsolya Nemeth, Mia Rakic, Stéphanie Tubert‐Jeannin, Raimondo Ascione, Francesco D'Aiuto, James Deschner, Thomas Dietrich, Mili Doshi, Julian Fisher, Ramón Juanatey, Phoebus Madianos, Katalin Nagy, Barry Quinn, Saulė Skinkytė, Lina Stangvaltaite‐Mouhat, Maria van den Muijsenbergh, Josep Vilaseca, Nicola West, Anton Sculean, Andreas Stavropoulos, Kenneth Eaton, Joint EFP/EADPH Working Group   +29 more
wiley   +1 more source

Editorial: Synovial Tissue: Turning the Page to Precision Medicine in Arthritis?

Frontiers in Medicine, 2021
Carl Kieran Orr, Frances Humby, Frances Humby, João Eurico Fonseca, João Eurico Fonseca   +4 more
doaj   +1 more source

Diagnostic and immunophenotypic contribution of ultrasound-guided synovial biopsy in inflammatory arthritis: Real-world experience from a tertiary rheumatology center

Ulusal Romatoloji Dergisi
Objective: Synovial tissue-based assessment has re-emerged as a useful approach for characterizing disease heterogeneity in inflammatory arthritis; however, real-world data on the diagnostic and immunophenotypic contribution of ultrasound-guided synovial
Gülnur Çelik Yılmaz, Hakan Apaydın, Halit Üner, Gözde Elif Taşar Kapaklı, Mehmet İhsan Başkaya, Cem Özişler, Alper Sarı, Sevinç Can Sandıkçı, Emine Gözde Aydemir Gülöksüz, Ekin Başak Doğancı, Melih Pamukcu   +10 more
doaj   +1 more source

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2261-2273, November 2026.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher, Iain B. McInnes, Enrique R. Soriano, Joseph F. Merola, Paul Bird, Vinod Chandran, Edaire Cheng, Elena Reynoso, Warner Chen, Maoji Li, Lianne S. Gensler, Philip J. Mease, Christopher T. Ritchlin   +12 more
wiley   +1 more source

A standardized surgical technique for debridement, antibiotics and implant retention improves treatment success rates in acute periprosthetic knee infection

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 11, Page 4041-4048, November 2026.
Abstract Purpose Results after debridement, antibiotics and implant retention (DAIR) for acute periprosthetic knee joint infections (PJIs) vary widely. Although data are limited, surgeon expertise and surgical technique likely influence outcomes. Standardized DAIR performed by surgeons within a multidisciplinary team (MDT) dedicated to the treatment of
Guillermo Sánchez‐Rosenberg, Anna Bartsch, Mario Morgenstern, Richard Kuehl, Martin Clauss   +4 more
wiley   +1 more source

Idiopathic immune‐mediated polyarthritis in a dog associated with ionised hypercalcaemia and probable ischaemic dermatopathy

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 5‐year‐old, spayed, female Shiba Inu was presented with a 6‐week history of reduced appetite, lethargy and generalised stiffness, which showed only limited improvement despite anti‐inflammatory treatment. The most significant clinical abnormalities were pyrexia, stiffness, pain on joint manipulation and cutaneous lesions. Laboratory findings
Jeanne Bergeat, Eddy Nassif, Sarah Berger, Isabelle Lagrange, Noëlle Cochet‐Faivre, Pierre Deshuillers, Maxime Kurtz   +6 more
wiley   +1 more source