Results 191 to 200 of about 19,285 (227)

PATHOGENESIS OF RHEUMATOID ARTHRITIS: THE ROLE OF SYNOVIOCYTES

Rheumatic Disease Clinics of North America, 2001
Considering the characteristics of RA synovial tissues such as marked proliferation and invasion to adjacent tissues, comparisons with transformed or neoplastic tissue are natural. RA synovial tissues or cells are not truly malignant, but they have many features of transformation, denoted as "partial transformation" in this article.
Y, Yamanishi, G S, Firestein
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Endothelin-1 Production by Human Synoviocytes

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1998
Immunoreactive (ir)-endothelin (ET)-l concentrations in serum samples and synovial fluids from patients with rheumatoid arthritis were higher than concentrations in sera obtained from healthy volunteers. No significant difference in ir-ET-1 concentrations in synovial fluid was observed between rheumatoid arthritis patients and osteoarthritis patients ...
H, Yoshida, Y, Imafuku, M, Ohhara, M, Miyata, R, Kasukawa, K, Ohsumi, J, Horiuchi   +6 more
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Chondroid Synoviocytic Neoplasm: A Clinicopathologic, Immunohistochemical, and Molecular Genetic Study of a Distinctive Tumor of Synoviocytes

Modern Pathology
Tumors resembling tenosynovial giant cell tumor (TGCT) but additionally forming chondroid matrix are rare and most often involve the temporomandibular joint (TMJ). We studied 21 tumors consisting of synoviocytes (large, eosinophilic mononuclear cells containing hemosiderin) and chondroid matrix to better understand these unusual neoplasms.
Erica Y. Kao, Fisun Ardic, Numrah Fadra, Jessica D. Hohenstein, Rohini Mopuri, Doris E. Wenger, Lukas Streich, Lisa M. Hines, Andrew L. Folpe   +8 more
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Characterization of Adenosine Receptors in Bovine Chondrocytes and Fibroblast-Like Synoviocytes Exposed to Low Frequency Low Energy Pulsed Electromagnetic Fields

Osteoarthritis and Cartilage, 2008
SummaryObjectiveThe present study describes the presence and binding parameters of the A1, A2A, A2B and A3 adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes.
Stefania Gessi, Fabrizio Vincenzi, Alessia Ongaro   +2 more
exaly   +2 more sources

GREM1 Is a Key Regulator of Synoviocyte Hyperplasia and Invasiveness

The Journal of Rheumatology, 2016
Objective.To investigate the expression of Gremlin 1 (GREM1), an antagonist of bone morphogenetic protein, in rheumatoid arthritis (RA) synovia and its involvement in the hyperplasia and invasiveness of fibroblast-like synoviocytes of RA (RA-FLS).Methods.Computational analysis was introduced to identify FLS-predominant regulators.
Han, Eun-Jin, Yoo, Seung-Ah, Kim, Gi-Myo, Hwang, Daehee, Cho, Chul-Soo, You, Sungyong, Kim, Wan-Uk   +6 more
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Synoviocytes. Autonomous drivers of chronicity?

2014
Background: Immunization with Glucose-6-phosphate isomerase (G6PI) induces arthritis in susceptible strains of mice. Depletion of regulatory T cells (Tregs) prior to immunization switches the usually acute, self-limiting course to a non-remitting, destructive arthritis. This provides a possibility to[for full text, please go to the a.m. URL]
Böttcher, M, Schett, G, Falk, C, Irmler, I, Wunrau, C, Korb-Pap, A, Pap, T, Kamradt, T   +7 more
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Regulation of Apoptosis in Rheumatoid Synoviocytes

2002
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by early synovitis following synovial proliferation and infiltration of various inflammatory cells (1,2). The process of disease progression, characterized by activation and hyperplasia of synoviocytes, mainly of synovial fibroblasts, results in cartilage and bone destruction (1,2)
Kusuki Nishioka, Tetsuya Kobayashi
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Regulation of the expression of adhesion molecules by human synoviocytes

Seminars in Arthritis and Rheumatism, 1992
The capacity of synoviocytes to participate in inflammatory responses may be altered by the cytokine-enhanced expression of adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1). To examine this possibility, the ability of selected cytokines to enhance ICAM-1 expression was examined.
H B, Lindsley, D D, Smith, L S, Davis, A E, Koch, P E, Lipsky   +4 more
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The effect of gallium nitrate on synoviocyte MMP activity

Biochimie, 2000
Gallium, a group IIIa metal salt, has been demonstrated to be an effective immunosuppressive agent. Gallium has also been shown to inhibit the production of inflammatory cytokines, such as IL-1beta, produced by macrophage-like cells in vitro. To further characterize the effects of gallium on the inflammatory process, we examined the effects of gallium ...
F S, Panagakos, E, Kumar, C, Venescar, P, Guidon   +3 more
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IMMUNOHISTOLOGIC STUDIES OF SYNOVIOCYTES AND SYNOVIAL EXUDATE CELLS

The Journal of Experimental Medicine, 1971
Inclusions were demonstrated in normal polymorphonuclear cells incubated with rheumatoid factor-positive synovial fluid. These stained positively for IgG, IgM, and the ß1C component of complement. When normal polymorphonuclear cells were incubated with factor-negative rheumatoid fluid, inclusions were not obtained.
E R, Hurd, T D, Kinsella, M, Ziff
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