Results 11 to 20 of about 2,467,465 (249)
AbstractSynthesis automatically constructs an implementation that satisfies a given logical specification. In this paper, we study the live synthesis problem, where the synthesized implementation replaces an already running system. In addition to satisfying its own specification, the synthesized implementation must guarantee a sound transition from the
Finkbeiner, Bernd +2 more
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Shield synthesis is an approach to enforce safety properties at runtime. A shield monitors the system and corrects any erroneous output values instantaneously. The shield deviates from the given outputs as little as it can and recovers to hand back control to the system as soon as possible.
Bettina Könighofer +6 more
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Two ethyleneglycol esters of 1-pyrene carboxylic acid were studied as chemosensors for the fluorescence “turn-off” detection of two nitro-containing analytes, such as antiviral drug Riamilovir (Triazavirin ®) and herbicidal agent dinitro-ortho-cresol ...
I. S. Kovalev +7 more
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Bispyrenylalkane Chemosensor for the Naked-eye Detection of Nitro-explosives
Pyrene-based compounds have a great potential as fluorescent chemosensors for various analytes including common nitro-explosives, such as 2,4,6-trinitrotoluene (TNT).
I. S. Kovalev +8 more
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Synthetic chemistry has traditionally relied on reactions between reactants of high chemical potential and transformations that proceed energetically downhill to either a global or local minimum (thermodynamic or kinetic control). Catalysts can be used to manipulate kinetic control, lowering activation energies to influence reaction outcomes.
Stefan Borsley +3 more
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3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors
SARS-CoV-2 nsp14 guanine-N7-methyltransferase plays an important role in the viral RNA translation process by catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to viral mRNA cap.
Olga Bobileva +9 more
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Evidence synthesis facilitates a more robust understanding of generalities in ecology and evolution, as well as the effectiveness of conservation interventions. However, as synthesis methods become embedded in research workflows, it is imperative that the next generation of researchers receives sufficient training.
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Nowadays, current global environmental problems include measures to eliminate or reduce the negative impact of chemicals from petroleum sources and, therefore, the use of materials from natural resources is increasingly recommended.
Yahya Bachra +4 more
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Glutathione (GSH) is present in all mammalian tissues as the most abundant non-protein thiol that defends against oxidative stress. GSH is also a key determinant of redox signaling, vital in detoxification of xenobiotics, and regulates cell proliferation, apoptosis, immune function, and fibrogenesis.
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Synthesis of a double-charged cationic amphiphilic 1,4-dihydropyridine derivative with dodecyl ester groups at positions 3 and 5 of the 1,4-DHP ring was performed starting from Hantzsch type cyclization of dodecyl acetoacetate, 2-naphthaldehyde and ...
Martins Rucins +5 more
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