Results 11 to 20 of about 7,229,609 (313)

A Path to Improved Alzheimer’s Care: Simulating Long-Term Health Outcomes of Lecanemab in Early Alzheimer’s Disease from the CLARITY AD Trial

open access: yesNeurology and Therapy, 2023
Introduction Alzheimer’s disease (AD), a progressive neurodegenerative disease, is the main cause of dementia and one of the leading causes of death for elderly people in the USA.
Amir Abbas Tahami Monfared   +6 more
doaj   +1 more source

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors

open access: yesMolecules, 2023
SARS-CoV-2 nsp14 guanine-N7-methyltransferase plays an important role in the viral RNA translation process by catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to viral mRNA cap.
Olga Bobileva   +9 more
doaj   +1 more source

Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline

open access: yesBritish medical journal, 2020
In systematic reviews that lack data amenable to meta-analysis, alternative synthesis methods are commonly used, but these methods are rarely reported. This lack of transparency in the methods can cast doubt on the validity of the review findings.
M. Campbell   +11 more
semanticscholar   +1 more source

Estimated Societal Value of Lecanemab in Patients with Early Alzheimer’s Disease Using Simulation Modeling

open access: yesNeurology and Therapy, 2023
Introduction Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with memory, cognitive, and behavioral deficits, and brings significant economic burden on caregivers and healthcare systems.
Amir Abbas Tahami Monfared   +6 more
doaj   +1 more source

Large-Area Synthesis of High-Quality and Uniform Graphene Films on Copper Foils [PDF]

open access: yesScience, 2009
Growing Graphene The highest quality graphene samples, single-atom-thick layers of carbon, are suspended flakes exfoliated from graphite, but these samples are very small in size (square micrometers).
Xuesong Li   +12 more
semanticscholar   +1 more source

Rats with congenital hydronephrosis show increased susceptibility to renal ischemia‐reperfusion injury

open access: yesPhysiological Reports, 2020
Many drug candidates have shown significant renoprotective effects in preclinical models; however, there is no clinically used effective pharmacotherapy for acute kidney injury.
Reinis Vilskersts   +7 more
doaj   +1 more source

Detection of Anti-viral Drug Riamilovir and Herbicides in Aqueous Media by Using Pyrene-based Fluorescent Chemosensors

open access: yesChimica Techno Acta, 2021
Two ethyleneglycol esters of 1-pyrene carboxylic acid were studied as chemosensors for the fluorescence “turn-off” detection of two nitro-containing analytes, such as antiviral drug Riamilovir (Triazavirin ®) and herbicidal agent dinitro-ortho-cresol ...
I. S. Kovalev   +7 more
doaj   +1 more source

Low‐intensity exercise stimulates bioenergetics and increases fat oxidation in mitochondria of blood mononuclear cells from sedentary adults

open access: yesPhysiological Reports, 2020
Aim Exercise training induces adaptations in muscle and other tissue mitochondrial metabolism, dynamics, and oxidative phosphorylation capacity. Mitochondrial fatty acid oxidation was shown to be pivotal for the anti‐inflammatory status of immune cells ...
Edgars Liepinsh   +9 more
doaj   +1 more source

Stellar population synthesis at the resolution of 2003 [PDF]

open access: yes, 2003
We present a new model for computing the spectral evolution of stellar populations at ages between 1 x 10 5 and 2 x 10 1 0 yr at a resolution of 3 A across the whole wavelength range from 3200 to 9500 A for a wide range of metallicities.
G. Bruzual, S. Charlot
semanticscholar   +1 more source

Bio-inspired synthesis of xishacorenes A, B, and C, and a new congener from fuscol

open access: yesChemical Science, 2019
In this manuscript, we describe the conversion of fuscol, a natural product isolated in 1978, to xishacorenes A, B, and C, isolated in 2017, as well as a previously unreported congener, which we have named xishacorene D.
Alexander R Rovira   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy