Results 61 to 70 of about 12,982,812 (373)

Genetic inactivation of the sigma-1 chaperone protein results in decreased expression of the R2 subunit of the GABA-B receptor and increased susceptibility to seizures

open access: yesNeurobiology of Disease, 2021
There is a growing body of evidence demonstrating the significant involvement of the sigma-1 chaperone protein in the modulation of seizures. Several sigma-1 receptor (Sig1R) ligands have been demonstrated to regulate the seizure threshold in acute and ...
Edijs Vavers   +9 more
doaj   +1 more source

Application of Permutation Group Theory in Reversible Logic Synthesis

open access: yes, 2016
The paper discusses various applications of permutation group theory in the synthesis of reversible logic circuits consisting of Toffoli gates with negative control lines.
CH Bennett   +8 more
core   +1 more source

SYNTHESIATORS. SOUND SYNTHESIS METHODS

open access: yes, 2022
Modern musical instruments offer ample opportunities for working with writing music in various genres. The device of this or that tool directly affects its quality and characteristics. The article discusses sound synthesis methods that are used in various synthesizers.
N.S. Ananin, B.M. Shtein
openaire   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Tailoring FPOX enzymes for enhanced stability and expanded substrate recognition

open access: yesScientific Reports, 2023
Fructosyl peptide oxidases (FPOX) are deglycating enzymes that find application as key enzymatic components in diabetes monitoring devices. Indeed, their use with blood samples can provide a measurement of the concentration of glycated hemoglobin and ...
Hajar Estiri   +8 more
doaj   +1 more source

Are There Good Mistakes? A Theoretical Analysis of CEGIS

open access: yes, 2014
Counterexample-guided inductive synthesis CEGIS is used to synthesize programs from a candidate space of programs. The technique is guaranteed to terminate and synthesize the correct program if the space of candidate programs is finite. But the technique
Jha, Susmit, Seshia, Sanjit A.
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Synthesis of porous silicates [PDF]

open access: yes, 1995
The issues of importance and future concern in the synthesis of porous silicates and porous materials that contain a large fraction of silica, e.g. zeolites and other crystalline molecular sieves, are reviewed. The thermodynamics of zeolite synthesis are
Davis­, M. E., Helmkamp, M. M.
core   +1 more source

Interferometry and Synthesis in Radio Astronomy [PDF]

open access: yes, 2017
Preface to the Second Edition. Preface to the First Edition. Introduction and Historical Review. Introductory Theory of Interferometry and Synthesis Imaging. Analysis of the Interferometer Response. Geometric Relationships and Polarimetry.
Jacob Baars
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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