Results 61 to 70 of about 9,706,454 (336)

BIF : a behavioral intermediate format for high level synthesis [PDF]

, 1989
This report describes a new intermediate format for behavioral synthesis systems, based on annotated state tables. It supports user control of the synthesis process by allowing specification of partial design structures, user-bindings and user ...
Dutt, Nikil D., Gajski, Daniel D., Hadley, Tedd   +2 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates

Molecules, 2015
The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions.
Brigita Vigante, Martins Rucins, Aiva Plotniece, Karlis Pajuste, Iveta Luntena, Brigita Cekavicus, Egils Bisenieks, Rufus Smits, Gunars Duburs, Arkadij Sobolev   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Predicting antibacterial activity of some Curcumin compounds: Fingerprint-based 2D-QSAR models

Scientific African
The strong spreads of bacterial infections, caused inter alia by the strong bacterial resistance to drugs, have impelled scientists to look for new antimicrobial agents.
Hajar Tebbaai, Naoual El Hamdani, Said Byadi, Aziz Aboulmouhajir   +3 more
doaj   +1 more source

Extended AIGER Format for Synthesis [PDF]

, 2014
We extend the AIGER format, as used in HWMCC, to a format that is suitable to define synthesis problems with safety specifications. We recap the original format and define one format for posing synthesis problems and one for solutions of synthesis ...
Jacobs, Swen
core  

Scalable virtual viewpoint image synthesis for multiple camera environments [PDF]

, 2005
One of the main aims of emerging audio-visual (AV) applications is to provide interactive navigation within a captured event or scene. This paper presents a view synthesis algorithm that provides a scalable and flexible approach to virtual viewpoint ...
Cooke, Eddie, O'Connor, Noel E.
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Advances in biosynthesis of chiral amide herbicides and the key enzymes: dimethenamid-P and S-metolachlor as case studies

Bioresources and Bioprocessing
Chiral amide herbicides represent a significant class of agrochemicals, widely used for effective weed control. Prominent examples include S-metolachlor and dimethenamid-P, both of which share the intermediate (S)-1-methoxy-2-propylamine, a key ...
Feng Cheng, Yi-Ling Zhou, Dan-Chen Yang, Ding-Yi Zhao, Ya-Ping Xue, Yu-Guo Zheng   +5 more
doaj   +1 more source

Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]

, 2004
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Fischer, S., Jungst, C., Jungst, D., Parhofer, K. G., Sauter, G. H., Thiessen, K.   +5 more
core   +1 more source