FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Water for food, water for life: a comprehensive assessment of water management in agriculture: summary. In Arabic [PDF]
Water management / Irrigation management / Policy / Water scarcity / Poverty / Water rights / Ecosystems / Rainfed ...
Molden, David
core
Application of Transition Metal Catalysis to Small Molecule Synthesis [PDF]
, 2006 Over the past decade, transition metal catalysis has developed into a new field in organic synthesis, enabling numerous synthetic transformations that were previously not feasible.
Morrill, Christie
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cellophane-Based Membranes for Purification of Aqueous Media from Various Pollutants
Учёные записки Казанского университета: Серия Естественные наукиThe process of nanofiltration purification of water from various organic pollutants was examined. Cellophane film made from cheap natural raw materials was used as a membrane.
A. A. Yushkin +5 more
doaj +1 more source
Bridging high-level synthesis to RTL technology libraries [PDF]
, 1991 The output of high-level synthesis typically consists of a netlist of generic RTL components and a state sequencing table. While module generators and logic synthesis tools can be used to map RTL components into standard cells or layout geometries, they ...
Dutt, Nikil D., Kipps, James R.
core
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation
Nature Communications, 2016 Formation of vicinal, quaternary stereocentres is challenging, but such products are commonly encountered in nature. Here, the authors report a palladium catalysed process to form vicinal quaternary carbons via propargylation, including in enantiopure ...
Xin Huang +5 more
doaj +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source