Results 71 to 80 of about 7,229,609 (313)

Advances in biosynthesis of chiral amide herbicides and the key enzymes: dimethenamid-P and S-metolachlor as case studies

open access: yesBioresources and Bioprocessing
Chiral amide herbicides represent a significant class of agrochemicals, widely used for effective weed control. Prominent examples include S-metolachlor and dimethenamid-P, both of which share the intermediate (S)-1-methoxy-2-propylamine, a key ...
Feng Cheng   +5 more
doaj   +1 more source

Human-Centric Program Synthesis [PDF]

open access: yesarXiv, 2019
Program synthesis techniques offer significant new capabilities in searching for programs that satisfy high-level specifications. While synthesis has been thoroughly explored for input/output pair specifications (programming-by-example), this paper asks: what does program synthesis look like beyond examples? What actual issues in day-to-day development
arxiv  

Correct-by-Design Teamwork Plans for Multi-Agent Systems [PDF]

open access: yesarXiv, 2023
We propose Teamwork Synthesis, a version of the distributed synthesis problem with application to teamwork multi-agent systems. We reformulate the distributed synthesis question by dropping the fixed interaction architecture among agents as input to the problem.
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Cellophane-Based Membranes for Purification of Aqueous Media from Various Pollutants

open access: yesУчёные записки Казанского университета: Серия Естественные науки
The process of nanofiltration purification of water from various organic pollutants was examined. Cellophane film made from cheap natural raw materials was used as a membrane.
A. A. Yushkin   +5 more
doaj   +1 more source

Extended AIGER Format for Synthesis [PDF]

open access: yesarXiv, 2014
We extend the AIGER format, as used in HWMCC, to a format that is suitable to define synthesis problems with safety specifications. We recap the original format and define one format for posing synthesis problems and one for solutions of synthesis problems in this setting.
arxiv  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation

open access: yesNature Communications, 2016
Formation of vicinal, quaternary stereocentres is challenging, but such products are commonly encountered in nature. Here, the authors report a palladium catalysed process to form vicinal quaternary carbons via propargylation, including in enantiopure ...
Xin Huang   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy