Results 1 to 10 of about 2,952,613 (401)

Synthetic Biology in Natural Product Biosynthesis. [PDF]

Chem Rev
Synthetic biology has played an important role in the renaissance of natural products research during the post-genomics era. The development and integration of new tools have transformed the workflow of natural product discovery and engineering ...
Seshadri K, Abad AND, Nagasawa KK, Yost KM, Johnson CW, Dror MJ, Tang Y.   +6 more
europepmc   +2 more sources

Applications of synthetic biology in medical and pharmaceutical fields

Signal Transduction and Targeted Therapy, 2023
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful bioproperties. During the past decades, progresses have been made to build delicate biocircuits, standardized biological building blocks and to develop various ...
Xu Yan, Xu Liu, Cuihuan Zhao, Guoqiao Chen   +3 more
semanticscholar   +1 more source

Recent Advances in CRISPR-Cas Technologies for Synthetic Biology

Journal of Microbiology, 2023
With developments in synthetic biology, “engineering biology” has emerged through standardization and platformization based on hierarchical, orthogonal, and modularized biological systems.
Song Hee Jeong, Ho Joung Lee, S. J. Lee
semanticscholar   +1 more source

Enabling technology and core theory of synthetic biology

Science China Life Sciences, 2023
Synthetic biology provides a new paradigm for life science research (“build to learn”) and opens the future journey of biotechnology (“build to use”).
Xian-En Zhang, Chenli Liu, Junbiao Dai, Yingjin Yuan, Caixia Gao, Yan Feng, Bian Wu, Ping Wei, Chun You, Xiaowo Wang, Tong Si   +10 more
semanticscholar   +1 more source

Dynamic feedback regulation for efficient membrane protein production using a small RNA-based genetic circuit in Escherichia coli

Microbial Cell Factories, 2022
Background Membrane proteins (MPs) are an important class of molecules with a wide array of cellular functions and are part of many metabolic pathways.
Chiara Guidi, Lien De Wannemaeker, Jasmine De Baets, Wouter Demeester, Jo Maertens, Brecht De Paepe, Marjan De Mey   +6 more
doaj   +1 more source

Synthetic biology: Learning the way toward high-precision biological design

PLoS Biology, 2023
Since its inception, synthetic biology has overcome many technical barriers but is at a crossroads for high-precision biological design. Devising ways to fully utilize big biological data may be the key to achieving greater heights in synthetic biology.
Shohei Kitano, Ciai Lin, J. Foo, M. Chang   +3 more
semanticscholar   +1 more source

Biosensor-driven, model-based optimization of the orthogonally expressed naringenin biosynthesis pathway

Microbial Cell Factories, 2022
Background The rapidly expanding synthetic biology toolbox allows engineers to develop smarter strategies to tackle the optimization of complex biosynthetic pathways.
Maarten Van Brempt, Andries Ivo Peeters, Dries Duchi, Lien De Wannemaeker, Jo Maertens, Brecht De Paepe, Marjan De Mey   +6 more
doaj   +1 more source

On the Choice of the Right Plasmid Vector(s) in the Times of Synthetic Biology. [PDF]

Microb Biotechnol
de Lorenzo V, Martínez-García E.
europepmc   +2 more sources

The living interface between synthetic biology and biomaterial design

Nature Materials, 2022
Recent far-reaching advances in synthetic biology have yielded exciting tools for the creation of new materials. Conversely, advances in the fundamental understanding of soft-condensed matter, polymers and biomaterials offer new avenues to extend the ...
Allen P. Liu, Eric A. Appel, P. Ashby, Brendon M. Baker, Elisa Franco, Luo Gu, K. Haynes, Neel S. Joshi, April M. Kloxin, P. Kouwer, J. Mittal, Leonardo Morsut, V. Noireaux, S. Parekh, Rebecca Schulman, Sindy K. Y. Tang, M. Valentine, Sebastián L. Vega, W. Weber, N. Stephanopoulos, Ovijit Chaudhuri   +20 more
semanticscholar   +1 more source

The all-E. coliTXTL toolbox 3.0: new capabilities of a cell-free synthetic biology platform

Synthetic Biology, 2021
The new generation of cell-free gene expression systems enables the prototyping and engineering of biological systems in vitro over a remarkable scope of applications and physical scales.
David Garenne, S. Thompson, A. Brisson, Aset Khakimzhan, V. Noireaux   +4 more
semanticscholar   +1 more source