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Synthetic biology-inspired development of live attenuated influenza vaccines [PDF]
npj VaccinesLive attenuated influenza vaccines (LAIVs) provide robust, cross-protective immunity but have traditionally been developed empirically and are associated with safety concerns.
Qisi Zhang +14 more
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Microbial Cell Factories, 2022 Background Membrane proteins (MPs) are an important class of molecules with a wide array of cellular functions and are part of many metabolic pathways.
Chiara Guidi +6 more
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Microbial Cell Factories, 2022 Background The rapidly expanding synthetic biology toolbox allows engineers to develop smarter strategies to tackle the optimization of complex biosynthetic pathways.
Maarten Van Brempt +6 more
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Nature Reviews Genetics, 2005 Chemistry is a broadly powerful discipline in contemporary science because it has the ability to create new forms of the matter that it studies. By doing so, chemistry can test models that connect molecular structure to behaviour without having to rely on what nature has provided.
Benner, Steven A., Sismour, A. Michael
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Synthetic Biology, 2023 AbstractSynthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms.
Ibrahim Aldulijan +12 more
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A synthetic transcription platform for programmable gene expression in mammalian cells
Nature Communications, 2022 Precise and scalable regulation of gene expression in mammalian cells is challenging. Here, the authors created a highly tunable CRISPR-based synthetic transcription system for programmable control of mammalian gene expression and cellular activity.
William C. W. Chen +13 more
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Org. Biomol. Chem., 2010 There is currently much excitement surrounding the rapidly growing discipline of synthetic biology, which utilizes the design and construction principles of engineering to develop, evolve and standardize biological components and systems. This systematic approach to improving and increasing the programmability and robustness of biological components is
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Translational synthetic biology [PDF]
Systems and Synthetic Biology, 2015 Synthetic biology is a recent scientific approach towards engineering biological systems from both pre-existing and novel parts. The aim is to introduce computational aided design approach in biology leading to rapid delivery of useful applications. Though the term reprogramming has been frequently used in the synthetic biology community, currently the
Mamta, Singh, Anuradha, Vaidya
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“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis
Methods and Protocols, 2019 Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
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