Results 1 to 10 of about 432,913 (337)

Synthetic biology—putting engineering into biology [PDF]

Bioinformatics, 2006
Abstract Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we review the case for this emerging discipline.
Matthias Heinemann, Sven Panke
openalex   +7 more sources

Synthetic RNA biology

RNA Biology
Beatrix Suess
doaj   +3 more sources

Functional Synthetic Biology

Synthetic Biology, 2023
AbstractSynthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms.
Ibrahim Aldulijan, Jacob Beal, Sonja Billerbeck, Jeff Bouffard, Gaël Chambonnier, Nikolaos Ntelkis, Isaac Guerreiro, Martin Holub, Paul Ross, Vinoo Selvarajah, Noah Sprent, Gonzalo Vidal, Alejandro Vignoni   +12 more
openaire   +5 more sources

Synthetic biology [PDF]

Nature Reviews Genetics, 2005
Chemistry is a broadly powerful discipline in contemporary science because it has the ability to create new forms of the matter that it studies. By doing so, chemistry can test models that connect molecular structure to behaviour without having to rely on what nature has provided.
Benner, Steven A., Sismour, A. Michael
openaire   +3 more sources

Dynamic feedback regulation for efficient membrane protein production using a small RNA-based genetic circuit in Escherichia coli

Microbial Cell Factories, 2022
Background Membrane proteins (MPs) are an important class of molecules with a wide array of cellular functions and are part of many metabolic pathways.
Chiara Guidi, Lien De Wannemaeker, Jasmine De Baets, Wouter Demeester, Jo Maertens, Brecht De Paepe, Marjan De Mey   +6 more
doaj   +1 more source

Environment and synthetic biology. [PDF]

Synth Syst Biotechnol
Tang H, Song M.
europepmc   +4 more sources

Biosensor-driven, model-based optimization of the orthogonally expressed naringenin biosynthesis pathway

Microbial Cell Factories, 2022
Background The rapidly expanding synthetic biology toolbox allows engineers to develop smarter strategies to tackle the optimization of complex biosynthetic pathways.
Maarten Van Brempt, Andries Ivo Peeters, Dries Duchi, Lien De Wannemaeker, Jo Maertens, Brecht De Paepe, Marjan De Mey   +6 more
doaj   +1 more source

Synthetic biology of hypoxia [PDF]

New Phytologist, 2020
SummarySynthetic biology can greatly aid the investigation of fundamental regulatory mechanisms and enable their direct deployment in the host organisms of choice. In the field of plant hypoxia physiology, a synthetic biology approach has recently been exploited to infer general properties of the plant oxygen sensing mechanism, by expression of plant ...
Beatrice Giuntoli, Beatrice Giuntoli, Francesco Licausi, Francesco Licausi   +3 more
openaire   +4 more sources

Synthetic biology: biology by design [PDF]

Microbiology, 2013
Synthetic biology can be defined as the design and construction of novel biologically based parts, devices and systems, as well as the redesign of existing natural biological systems, for useful purposes. It builds on genetic engineering, being design-driven genetic engineering encompassing engineering concepts of standardization and abstraction (Endy,
Roberts, MAJ, Cranenburgh, RM, Stevens, MP, Oyston, PCF   +3 more
openaire   +4 more sources

A synthetic transcription platform for programmable gene expression in mammalian cells

Nature Communications, 2022
Precise and scalable regulation of gene expression in mammalian cells is challenging. Here, the authors created a highly tunable CRISPR-based synthetic transcription system for programmable control of mammalian gene expression and cellular activity.
William C. W. Chen, Leonid Gaidukov, Yong Lai, Ming-Ru Wu, Jicong Cao, Michael J. Gutbrod, Gigi C. G. Choi, Rachel P. Utomo, Ying-Chou Chen, Liliana Wroblewska, Manolis Kellis, Lin Zhang, Ron Weiss, Timothy K. Lu   +13 more
doaj   +1 more source