Results 21 to 30 of about 927,045 (311)

Engineering consortia by polymeric microbial swarmbots

Nature Communications, 2022
Most attempts to co-cultivate the artificial microbial communities fail mostly due to the mismatched rates of consumption and production of nutrients among subpopulations. Here, the authors develop a microbial swarmbot mediated spatial segregation method
Lin Wang, Xi Zhang, Chenwang Tang, Pengcheng Li, Runtao Zhu, Jing Sun, Yunfeng Zhang, Hua Cui, Jiajia Ma, Xinyu Song, Weiwen Zhang, Xiang Gao, Xiaozhou Luo, Lingchong You, Ye Chen, Zhuojun Dai   +15 more
doaj   +1 more source

Misconceptions of Synthetic Biology: Lessons from an Interdisciplinary Summer School [PDF]

, 2016
In 2014, an international group of scholars from various fields analysed the "societal dimensions" of synthetic biology in an interdisciplinary summer school. Here, we report and discuss the biologists' observations on the general perception of synthetic
Acevedo-Rocha, Carlos G., Chizzolini, Fabio, Rothschild, Lynn J., Verseux, Cyprien   +3 more
core   +2 more sources

BacillOndex: An Integrated Data Resource for Systems and Synthetic Biology [PDF]

, 2013
BacillOndex is an extension of the Ondex data integration system, providing a semantically annotated, integrated knowledge base for the model Gram-positive bacterium Bacillus subtilis. This application allows a user to mine a variety of B.
Allenby, Nick, Hallinan, Jennifer S., James, Katherine, Misirli, Goksel, Mullen, Joseph, Pocock, Matthew, Smith, Wendy, Wipat, Anil   +7 more
core   +2 more sources

Deconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists

Nature Communications
Synthetic biology allows us to reuse, repurpose, and reconfigure biological systems to address society’s most pressing challenges. Developing biotechnologies in this way requires integrating concepts across disciplines, posing challenges to educating ...
Ashty S. Karim, Dylan M. Brown, Chloé M. Archuleta, Sharisse Grannan, Ludmilla Aristilde, Yogesh Goyal, Josh N. Leonard, Niall M. Mangan, Arthur Prindle, Gabriel J. Rocklin, Keith J. Tyo, Laurie Zoloth, Michael C. Jewett, Susanna Calkins, Neha P. Kamat, Danielle Tullman-Ercek, Julius B. Lucks   +16 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Progression in the In Vitro Macrophage Expansion

Journal of Immunology Research
Macrophages play essential roles in homeostasis and disease, and they were considered terminally differentiated cells that cannot proliferate. However, growing evidence shows that macrophages can self-renew in homeostasis and multiple pathological states
Yunpeng Wei, Jingzhao Yang, Wenhong Zu, Mengran Wang, Yong Zhao   +4 more
doaj   +1 more source

BrisSynBio:a BBSRC/EPSRC-funded Synthetic Biology Research Centre [PDF]

, 2016
BrisSynBio is the Bristol-based Biotechnology and Biological Sciences Research Council (BBSRC)/Engineering and Physical Sciences Research Council (EPSRC)-funded Synthetic Biology Research Centre. It is one of six such Centres in the U.K.
Race, Paul R, Sedgley, Kathleen R, Woolfson, Dek N   +2 more
core   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker’s yeast

Nature Communications, 2017
Filamentous fungi are a valuable source of natural therapeutic products such as antibiotics. Here the authors engineer monocellularS. cerevisiaeto perform complex secondary metabolism typical of multicellular fungi in order to demonstrate biosynthesis ...
Ali R. Awan, Benjamin A. Blount, David J. Bell, William M. Shaw, Jack C.H. Ho, Robert M. McKiernan, Tom Ellis   +6 more
doaj   +1 more source

Phosphite synthetic auxotrophy as an effective biocontainment strategy for the industrial chassis Pseudomonas putida

Microbial Cell Factories, 2022
The inclusion of biosafety strategies into strain engineering pipelines is crucial for safe-by-design biobased processes. This in turn might enable a more rapid regulatory acceptance of bioengineered organisms in both industrial and environmental ...
Enrique Asin-Garcia, Christos Batianis, Yunsong Li, James D. Fawcett, Ivar de Jong, Vitor A. P. Martins dos Santos   +5 more
doaj   +1 more source