Results 21 to 30 of about 432,913 (337)
A synthetic microbial biosensor for high-throughput screening of lactam biocatalysts
Nature Communications, 2018 Efficient biosynthesis of lactams is still undesirable due to lacking of suitable enzyme. Here, the authors develop a sensitive transcription factor-based biosensor for high-throughput screening of marine metagenome and find a cyclase that can cyclize ω ...
Soo-Jin Yeom +10 more
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Developing an NLP-based Recommender System for the Ethical, Legal, and Social Implications of Synthetic Biology [PDF]
arXiv, 2022 Synthetic biology is an emerging field that involves the engineering and re-design of organisms for purposes such as food security, health, and environmental protection. As such, it poses numerous ethical, legal, and social implications (ELSI) for researchers and policy makers.
arxiv
Engineering Biology, 2019 Clostridium autoethanogenum is an industrial microbe used for the commercial-scale production of ethanol from carbon monoxide. While significant progress has been made in the attempted diversification of this bioprocess, further improvements are ...
Rupert O.J. Norman +13 more
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Harnessing bioengineered microbes as a versatile platform for space nutrition
Nature Communications, 2022 Long-duration human space travel creates challenges for maintaining healthy diets. Here the authors discuss using synthetic biology approaches to modify yeast into an optimal, and enjoyable, food production platform.
Briardo Llorente +4 more
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Synthetic biology's flywheel [PDF]
EMBO reports, 2012 Producing drugs and chemicals efficiently from cells remains a major challenge. Synthetic biologists need to invent the equivalents of the crank and flywheel to improve productivity.
openaire +3 more sources
Editorial–Synthetic Biology [PDF]
Nucleic Acids Research, 2010 Synthetic biology builds upon over 35 years of genetic engineering. For example, in the 1970s methods were invented for using enzymes to rework DNA. Applying these tools, bacteria were engineered to yield relevant products such as growth hormones and insulin.
James J. Collins +3 more
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Scientific Reports, 2021 Coiled-coil (CC) dimer-forming peptides are attractive designable modules for mediating protein association. Highly stable CCs are desired for biological activity regulation and assay.
Tjaša Plaper +6 more
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Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker’s yeast
Nature Communications, 2017 Filamentous fungi are a valuable source of natural therapeutic products such as antibiotics. Here the authors engineer monocellularS. cerevisiaeto perform complex secondary metabolism typical of multicellular fungi in order to demonstrate biosynthesis ...
Ali R. Awan +6 more
doaj +1 more source
A synthetic biology approach for the design of genetic algorithms with bacterial agents [PDF]
arXiv, 2021 Bacteria have been a source of inspiration for the design of evolutionary algorithms. At the beginning of the 20th century synthetic biology was born, a discipline whose goal is the design of biological systems that do not exist in nature, for example, programmable synthetic bacteria.
arxiv
Synthetic Genomes for Synthetic Biology [PDF]
Journal of Molecular Cell Biology, 2010 A genome synthesized entirely from scratch has been used to replace the native genome of a living cell, thus creating a new cell. This achievement marks a new frontier in synthetic biology to design and create genomes for organisms with few genetic tools and for applications in areas of energy, health care and the environment.
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