Results 31 to 40 of about 2,952,613 (401)
Construction of an rAAV Producer Cell Line through Synthetic Biology
ACS Synthetic Biology, 2022 Recombinant adeno-associated viruses (rAAV) are important gene delivery vehicles for gene therapy applications. Their production relies on plasmid transfection or virus infection of producer cells, which pose a challenge in process scale-up.
Zion Lee +4 more
semanticscholar +1 more source
Synthetic biology's flywheel [PDF]
EMBO reports, 2012 Producing drugs and chemicals efficiently from cells remains a major challenge. Synthetic biologists need to invent the equivalents of the crank and flywheel to improve productivity.
openaire +2 more sources
Trends in Plant Science, 2015 Plant synthetic biology is an emerging field that combines engineering principles with plant biology toward the design and production of new devices. This emerging field should play an important role in future agriculture for traditional crop improvement, but also in enabling novel bioproduction in plants. In this review we discuss the design cycles of
Wusheng, Liu, C Neal, Stewart
openaire +2 more sources
Science Progress, 2014 Although both the most popular form of synthetic biology (SB) and chemical synthetic biology (CSB) share the biotechnologically useful aim of making new forms of life, SB does so by using genetic manipulation of extant microorganism, while CSB utilises classic chemical procedures in order to obtain biological structures which are non-existent in ...
CHIARABELLI, Cristiano, Luisi P.L.
openaire +3 more sources
Synthetic biology, engineering biology, market expectation
Engineering Biology, 2020 ‘Engineering biology’ is being increasingly adopted as a term by organisations that seek to deliver benefits from ‘synthetic biology’. However, are ‘engineering biology’ and ‘synthetic biology’ different words with the same meaning or do they signal ...
Lionel Clarke
doaj +1 more source
Inducible expression of large gRNA arrays for multiplexed CRISPRai applications
Nature Communications, 2022 CRISPR gene activation and inhibition has become a powerful synthetic tool for influencing the expression of native genes for foundational studies, cellular reprograming, and metabolic engineering.
William M. Shaw +7 more
doaj +1 more source
Genomics and synthetic biology as a viable option to intensify sustainable use of biodiversity [PDF]
, 2011 The Amazon basin is an area of mega-biodiversity. Different models have been proposed^1-8^ for the establishment of an effective conservation policy, increasing sustainability and adding value for biodiversity. Currently, a broad spectrum of technologies
Elibio L. Rech
core +3 more sources
Molecular and biochemical characterization of a novel isoprene synthase from Metrosideros polymorpha
BMC Plant Biology, 2018 Background Isoprene is a five-carbon chemical that is an important starting material for the synthesis of rubber, elastomers, and medicines. Although many plants produce huge amounts of isoprene, it is very difficult to obtain isoprene directly from ...
Soo-Jin Yeom +8 more
doaj +1 more source
Chemical communication between synthetic and natural cells: a possible experimental design [PDF]
, 2013 The bottom-up construction of synthetic cells is one of the most intriguing and interesting research arenas in synthetic biology. Synthetic cells are built by encapsulating biomolecules inside lipid vesicles (liposomes), allowing the synthesis of one or ...
D'Angelo, Francesca +5 more
core +3 more sources
Modular Synthetic Biology Toolkit for Filamentous Fungi
ACS Synthetic Biology, 2021 Filamentous fungi are highly productive cell factories, often used in industry for the production of enzymes and small bioactive compounds. Recent years have seen an increasing number of synthetic-biology-based applications in fungi, emphasizing the need
László Mózsik +5 more
semanticscholar +1 more source