Results 71 to 80 of about 434,962 (238)
Synthetic microbe-to-plant communication channels
Nature CommunicationsPlants and microbes communicate to collaborate to stop pests, scavenge nutrients, and react to environmental change. Microbiota consisting of thousands of species interact with each other and plants using a large chemical language that is interpreted by ...
Alice Boo +7 more
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Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9
Nature Communications, 2017 DNA degradation products are frequently found in the endosome, but how they regulate the activation of Toll-like receptors is not known. Here the authors show that single-stranded DNA as short as two nucleotides can enhance the ability of longer DNA ...
Jelka Pohar +5 more
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BMC BioinformaticsBackground Vaccines development in this millennium started by the milestone work on Neisseria meningitidis B, reporting the invention of Reverse Vaccinology (RV), which allows to identify vaccine candidates (VCs) by screening bacterial pathogens genome ...
Andrea Conte +6 more
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Genetic circuit characterization and debugging using RNA‐seq
Molecular Systems Biology, 2017 Genetic circuits implement computational operations within a cell. Debugging them is difficult because their function is defined by multiple states (e.g., combinations of inputs) that vary in time.
Thomas E Gorochowski +7 more
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arXiv, 2014 It is often stated that there are no laws in biology, where everything is contingent and could have been otherwise, being solely the result of historical accidents. Furthermore, the customary introduction of fundamental biological entities such as individual organisms, cells, genes, catalysts and motors remains largely descriptive; constructive ...
arxiv
New Approaches in Synthetic Biology: Abiotic Organelles and Artificial Cells Powered and Controlled by Light [PDF]
arXiv, 2019 One of the major goals of nanobionics and bottom-up synthetic biology is the development of artificial cell organelles for the creation of cell-like structures operating similar to biological systems with a minimalistic set of building blocks.
arxiv
Microbial BiotechnologyThe ability to regulate gene expression in multiple directions is crucial to maximise the production of microbial cell factories. However, the lack of a regulatory tool that can simultaneously activate and repress multiple genes restricts the ...
Yaru Chen +8 more
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Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria
Nature Communications, 2017 The double-strand breaks generated by CRISPR-Cas systems are the target of multiple DNA repair pathways. Here the authors find incompatibility between NHEJ and type II-A CRISPR-Cas systems due to Csn2 mediated inhibition of end-joining.
Aude Bernheim +6 more
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Storage‐D: A user‐friendly platform that enables practical and personalized DNA data storage
iMetaDeoxyribonucleic acid (DNA) has been suggested as a very promising medium for data storage in recent years. Although numerous studies have advocated for DNA data storage, its practical application remains obscure and there is a lack of a user‐oriented ...
Xiaoluo Huang +7 more
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