Results 31 to 40 of about 2,867,164 (299)

Carbon storage and DNA absorption in allophanic soils and paleosols [PDF]

, 2014
Andisols and andic paleosols dominated by the nanocrystalline mineral allophane sequester large amounts of carbon (C), attributable mainly to its chemical bonding with charged hydroxyl groups on the surface of allophane together with its physical ...
Louis A. Schipper, Cooper, Alan, Lowe, David J., Yu-Tuan Huang, G. Jock Churchman, Schipper, Louis A., Nicolas J. Rawlence, Rawlence, Nicolas J., David J. Lowe, Alan Cooper, Huang, Yu-Tuan, Churchman, G. Jock   +11 more
core   +1 more source

Blue light-activatable DNA for remote controlled logic gates in synthetic cells [PDF]

, 2023
Cell-free gene expression is a vital research tool to study biological systems in defined minimal environments and has promising applications in biotechnology.
Denis, Hartmann, Jefferson, Smith, Razia, Chowdhry, Michael, Booth   +3 more
core   +2 more sources

Flap endonuclease 1 and DNA-PKcs synergistically participate in stabilizing replication fork to encounter replication stress in glioma cells

Journal of Experimental & Clinical Cancer Research, 2022
Background Selectively utilizing alternative mechanisms to repair damaged DNA in essential factors deficient cancer facilitates tumor genetic evolution and contributes to treatment resistance.
Jing Zhang, Mu Chen, Ying Pang, Meng Cheng, Bingsong Huang, Siyi Xu, Min Liu, Hao Lian, Chunlong Zhong   +8 more
doaj   +1 more source

Building a global alliance of biofoundries

Nature Communications, 2019
Biofoundries provide an integrated infrastructure to enable the rapid design, construction, and testing of genetically reprogrammed organisms for biotechnology applications and research.
Nathan Hillson, Mark Caddick, Yizhi Cai, Jose A. Carrasco, Matthew Wook Chang, Natalie C. Curach, David J. Bell, Rosalind Le Feuvre, Douglas C. Friedman, Xiongfei Fu, Nicholas D. Gold, Markus J. Herrgård, Maciej B. Holowko, James R. Johnson, Richard A. Johnson, Jay D. Keasling, Richard I. Kitney, Akihiko Kondo, Chenli Liu, Vincent J. J. Martin, Filippo Menolascina, Chiaki Ogino, Nicola J. Patron, Marilene Pavan, Chueh Loo Poh, Isak S. Pretorius, Susan J. Rosser, Nigel S. Scrutton, Marko Storch, Hille Tekotte, Evelyn Travnik, Claudia E. Vickers, Wen Shan Yew, Yingjin Yuan, Huimin Zhao, Paul S. Freemont   +35 more
doaj   +1 more source

DNA-Based Synthetic Growth Factor Surrogates with Fine-Tuned Agonism [PDF]

, 2019
Designing synthetic surrogates of functional proteins is an important, albeit challenging, task in the field of chemistry. A strategy toward the design of synthetic agonists for growth factors or cytokine receptors that elicit a desired signal activity ...
Ryosuke Ueki (7298072), Momoko Akiyama (7332786), Shinsuke Sando (5833418)   +2 more
core   +3 more sources

Author Correction: Building a global alliance of biofoundries

Nature Communications, 2019
The original version of this Comment contained errors in the legend of Figure 2, in which the locations of the fifteenth and sixteenth GBA members were incorrectly given as ‘(15) Australian Genome Foundry, Macquarie University; (16) Australian Foundry ...
Nathan Hillson, Mark Caddick, Yizhi Cai, Jose A. Carrasco, Matthew Wook Chang, Natalie C. Curach, David J. Bell, Rosalind Le Feuvre, Douglas C. Friedman, Xiongfei Fu, Nicholas D. Gold, Markus J. Herrgård, Maciej B. Holowko, James R. Johnson, Richard A. Johnson, Jay D. Keasling, Richard I. Kitney, Akihiko Kondo, Chenli Liu, Vincent J. J. Martin, Filippo Menolascina, Chiaki Ogino, Nicola J. Patron, Marilene Pavan, Chueh Loo Poh, Isak S. Pretorius, Susan J. Rosser, Nigel S. Scrutton, Marko Storch, Hille Tekotte, Evelyn Travnik, Claudia E. Vickers, Wen Shan Yew, Yingjin Yuan, Huimin Zhao, Paul S. Freemont   +35 more
doaj   +1 more source

Programming cell entry of molecules via reversible synthetic DNA circuits on cell membrane

Fundamental Research, 2021
Cellular uptake of biomolecules is crucial for regulating cell function. However, powerful and biocompatible tools for dynamically manipulating the cell entry of single-stranded DNAs (ssDNAs) remain elusive.
Jiangbo Liu, Yirong Chen, Fan Li, Xiuhai Mao, Min Li, Xiaolei Zuo, Chunhai Fan   +6 more
doaj   +1 more source

Locus specific engineering of tandem DNA repeats in the genome of Saccharomyces cerevisiae using CRISPR/Cas9 and overlapping oligonucleotides

Scientific Reports, 2018
DNA repeats constitute a large part of genomes of multicellular eucaryotes. For a longtime considered as junk DNA, their role in genome organization and tuning of gene expression is being increasingly documented.
Astrid Lancrey, Alexandra Joubert, Jean-Baptiste Boulé   +2 more
doaj   +1 more source

DCs facilitate B cell responses against microbial DNA via DC-SIGN.

PLoS ONE, 2017
Microbial DNA is highly immunostimulatory and is sensed by endosomal pattern recognition receptors after release from internalized microbes. It is unclear how extracellular DNA released from dead microbes is delivered to endosomal PRRs to induce immune ...
Joris K Sprokholt, Marieke H Heineke, Tanja M Kaptein, John L van Hamme, Teunis B H Geijtenbeek   +4 more
doaj   +1 more source

Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells

Acta Pharmaceutica Sinica B, 2020
Breast cancer susceptibility gene 1 (BRCA1) is a tumor suppressor gene, which is frequently mutated in breast and ovarian cancers. BRCA1 plays a key role in the homologous recombination directed DNA repair, allowing its deficiency to act as a therapeutic
Baoyuan Zhang, Junfang Lyu, Eun Ju Yang, Yifan Liu, Changjie Wu, Lakhansing Pardeshi, Kaeling Tan, Qiang Chen, Xiaoling Xu, Chu-Xia Deng, Joong Sup Shim   +10 more
doaj   +1 more source