Results 61 to 70 of about 3,003,336 (196)
A Synthetic DNA with Unusual Base‐Pairing [PDF]
European Journal of Biochemistry, 1971 The alternating polydeoxynucleotide poly[d(A‐s4T) · d(A‐s4T)] with 4‐thiothymidine substituting for thymidine shows anomalous spectral and hydrodynamic properties which are inconsistent with a Watson‐Crick structure but agree with a model of a left‐handed double helix built up from Haschemeyer‐Sobell (reversed Hoogsteen) base‐pairs instead.Optical ...
E M, Gottschalk, E, Kopp, A G, Lezius
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Synthetic DNA for Cell‐Surface Engineering
Angewandte Chemie, 2021 AbstractThe cell membrane is not only a physical barrier, but also a functional organelle that regulates the communication between a cell and its environment. The ability to functionalize the cell membrane with synthetic molecules or nanostructures would advance cellular functions beyond what evolution has provided.
Peng Shi, Yong Wang
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Error-Free Synthetic DNA by Molecular Dictation. [PDF]
, 2021 Synthetic DNA is the linchpin of the rapidly accelerating biotechnological era and is perhaps the most promising candidate for long-term digital data storage.
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Synthetic chemistry of base-modified DNA and their biological applications
, 2002 Synthetic chemistry of base-modified DNA has provided a powerful tool for studying DNA-related subjects, in particular for understanding DNA damage and repair.
Xu, Yao-Zhong
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O-GlcNAcylation of YTHDF2 antagonizes ERK-dependent phosphorylation and inhibits lung carcinoma
Fundamental ResearchThe intracellular O-linked N-acetylglucosamine (O-GlcNAc) glycosylation mediates many signal transduction events and regulates tumorigenesis. Previously the RNA N6-methyladenosine (m6A) reader, YTH (YT521-B homology) domain 2 (YTHDF2), has been shown to ...
Jie Li +7 more
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Options for Synthetic DNA Order Screening, Revisited
mSphere, 2017 Gene synthesis providers affiliated with the International Gene Synthesis Consortium (IGSC) voluntarily screen double-stranded DNA (dsDNA) synthesis orders over 200 bp to check for matches to regulated pathogens and to screen customers.
Diane DiEuliis +2 more
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Nanoelectromechanics of Methylated DNA in a Synthetic Nanopore [PDF]
Biophysical Journal, 2009 Methylation of cytosine is a covalent modification of DNA that can be used to silence genes, orchestrating a myriad of biological processes including cancer. We have discovered that a synthetic nanopore in a membrane comparable in thickness to a protein binding site can be used to detect methylation.
Mirsaidov, U. +6 more
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A Highly Efficient Synthetic Vector: Nonhydrodynamic Delivery of DNA to Hepatocyte Nuclei in Vivo
, 2013 Multifunctional membrane-core nanoparticles, composed of calcium phosphate cores, arginine-rich peptides, cationic and PEGylated lipid membranes, and galactose targeting ligands, have been developed as synthetic vectors for efficient nuclear delivery of ...
Hu, YX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, 17 Chun Hui Rd, Yantai 264003, Shandong, Peoples R China. yunxiahu@yic.ac.cn +6 more
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India’s DNA synthesis landscape: regulatory frameworks, industry structure, and biosecurity gaps
Frontiers in Bioengineering and BiotechnologyIndia is among the world’s largest and fastest-growing bioeconomies and ranks third globally in the number of in-country custom DNA synthesis providers, yet it lacks a dedicated regulatory framework governing the synthesis, sale, and distribution of ...
Suryesh Kumar Namdeo, Mayra Ameneiros
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, 2009 There is currently much excitement surrounding the rapidly growing discipline of synthetic biology, which utilizes the design and construction principles of engineering to develop, evolve and standardize biological components and systems. This systematic
Ali Tavassoli, Tavassoli, Ali
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