Results 71 to 80 of about 3,003,336 (196)
Synthetic protein-conductive membrane nanopores built with DNA
Nature Communications, 2019 Nanopores have a wide range of applications in the field of sensing. Here the authors report on synthetic nanopores made of DNA and designed for the transit of folded proteins across membranes to allow for biosensing.
Tim Diederichs +8 more
doaj +1 more source
SemiSynBio: A new era for neuromorphic computing
Synthetic and Systems BiotechnologyNeuromorphic computing has the potential to achieve the requirements of the next-generation artificial intelligence (AI) systems, due to its advantages of adaptive learning and parallel computing. Meanwhile, biocomputing has seen ongoing development with
Ruicun Liu +8 more
doaj +1 more source
, 2018 The generation of synthetic poxviruses as described by Evans and colleagues and cloning of synthetic DNA using TAR in yeast are illustrated. Synthesized DNA fragments are assembled and cloned in a set of plasmids containing overlapping DNA fragments ...
Volker Thiel (78076)
core +1 more source
DNA-based biosensor platforms for the detection of TP53 mutation [PDF]
, 2012 A DNA-based assay for the detection of one-point mutation in TP53 gene, responsible for lung cancer, was developed using a surface plasmon resonance (SPR) and a quartz crystal microbalance (QCM) biosensor systems.
Altintas, Zeynep +3 more
core +1 more source
Modification of cellular DNA by synthetic aziridinomitosenes
Bioorganic & Medicinal Chemistry, 2015 Two synthetic aziridinomitosenes (AZMs), Me-AZM and H-AZM, structurally related to mitomycin C (MC) were evaluated for their anticancer activity against six cancer cell lines (HeLa, Jurkat, T47D, HepG2, HL-60, and HuT-78) and tested for their DNA-modifying abilities in Jurkat cells.
Mallory, Chris M. +4 more
openaire +4 more sources
Synthetic protein-binding DNA sponge as a tool to tune gene expression and mitigate protein toxicity
Nature Communications, 2020 Decoy binding sites are natural regulators of gene expression. Here the authors design synthetic DNA sponges that fine tune the performance of synthetic gene circuits in a simple yet systematic manner, expanding the synthetic biology toolkit for gene ...
Xinyi Wan +3 more
doaj +1 more source
Nucleases sintéticas: caracterização bioquímica e mecanismo de ação sobre DNA [PDF]
, 2006 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em QuímicaFoi estudada a interação de cinco complexos metálicos de Cu2+ com moléculas de DNA.
Oliveira, Mauricio César Bof de
core
DNA repair in cancer: emerging targets for personalized therapy
Cancer Management and Research, 2014 Rachel Abbotts, Nicola Thompson, Srinivasan Madhusudan University of Nottingham, Academic Unit of Oncology, Division of Oncology, School of Medicine, Nottingham University Hospitals, City Hospital Campus, Nottingham, UK Abstract: Genomic ...
Abbotts R, Thompson N, Madhusudan S
doaj
Polygraph: a software framework for the systematic assessment of synthetic regulatory DNA elements
Genome BiologyThe design of regulatory elements is pivotal in gene and cell therapy, where DNA sequences are engineered to drive elevated and cell-type specific expression.
Avantika Lal +4 more
doaj +1 more source
Recursive construction of perfect DNA molecules from imperfect oligonucleotides
Molecular Systems Biology, 2008 Making faultless complex objects from potentially faulty building blocks is a fundamental challenge in computer engineering, nanotechnology and synthetic biology.
Gregory Linshiz +6 more
doaj +1 more source