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Flavonoids and Their Synthetic Derivatives, Chemistry and Biological Applications - A Review
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Phytochemistry, 2021
Prenylated flavonoids, a unique class of flavonoids which combine a flavonoid skeleton and a lipophilic prenyl side-chain, possess great potential biological activities including cytotoxicity, anti-inflammation, anti-Alzheimer, anti-microbial, anti-oxidant, anti-diabetes, estrogenic, vasorelaxant and enzyme inhibition.
Shaochun, Shi +4 more
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Prenylated flavonoids, a unique class of flavonoids which combine a flavonoid skeleton and a lipophilic prenyl side-chain, possess great potential biological activities including cytotoxicity, anti-inflammation, anti-Alzheimer, anti-microbial, anti-oxidant, anti-diabetes, estrogenic, vasorelaxant and enzyme inhibition.
Shaochun, Shi +4 more
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Pharmacological studies on synthetic flavonoids: comparison with diazepam
Neuropharmacology, 1999The present experiments compared the central BZ-omega binding characteristics and pharmacological profiles of two synthetic flavonoids (6-bromoflavone and 6-bromo-3'-nitroflavone) with those of the benzodiazepine (BZ) diazepam. In vitro experiments showed that while diazepam displaced [3H]flumazenil binding to the GABA(A) receptor in membranes from rat
G, Griebel +4 more
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Flavonoids as stabilizers of fish oil: An alternative to synthetic antioxidants
Journal of the American Oil Chemists' Society, 1993The antioxidant activities against fish oil oxidation of six commercially available flavonoids and of five flavonoids purified from two Chilean native plants were compared to those ofdl‐α‐tocopherol and of two synthetic antioxidants, butylated hydroxytoluene and butylated hydroxyanisole.
NIETO, S +6 more
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A Short Review on Synthetic Methodologies of Flavonoids
Asian Journal of Pharmacy and Technology, 2022Flavonoids are the pigments present in plants which mostly found in terrestrial plants. Flavonoids are indeed a naturally present group of polyphenolic compounds present in plants. They were driven by the term "flavus," which means "yellow." It is a 15-carbon skeleton compound.
Mufliha Murtaza +5 more
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Advance in flavonoids biosynthetic pathway and synthetic biology
China Journal of Chinese Materia Medica, 2016Flavonoids are the valuable components in medicinal plants, which possess a variety of pharmacological activities, including anti-tumor, antioxidant and anti-inflammatory activities. There is an unambiguous understanding about flavonoids biosynthetic pathway, that is,2S-flavanones including naringenin and pinocembrin are the skeleton of other ...
Li-Qiu, Zou +4 more
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Chemistry and Synthetic Overview of Flavonoids
2019Flavonoids are widely distributed secondary metabolites in plants that are known to be present in different vegetables and fruits. The flavonoid groups include various subclasses of compounds such as flavanones, flavones, dihydroflavonols, flavonols, flavan-3-ols, anthocyanidins, isoflavones, proanthocyanidins, and chalcones with a C6-C3-C6 structure ...
Ajay Sharma +2 more
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New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity
Free Radical Biology and Medicine, 2001A series of 3,7-disubstituted-2(3',4'-dihydroxyphenyl) flavones has been studied as potential cardioprotective agents in doxorubicin antitumor therapy. The influence of substituents on the 3 and 7 position of the flavone nucleus on antioxidant activity cytotoxicity and cardioprotective properties was explored to improve the activity of our lead ...
van Acker, F.A.A. +5 more
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