Results 11 to 20 of about 1,134,240 (310)
Synthetic lipids and their role in defining macromolecular assemblies
Chemistry and Physics of Lipids, 2015 Lipids have a variety of physiological roles, ranging from structural and biophysical contributions to membrane functions to signaling contributions in normal and abnormal physiology. This review highlights some of the contributions made by Robert Bittman to our understanding of lipid assemblies through the production of synthetic lipid analogs in the ...
Parrill, Abby L.
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Ornithine lipids and other acyloxyacyl amino lipids: the coming-of-age story of a group of non-canonical membrane lipids [PDF]
Applied Microbiology and BiotechnologyOrnithine lipids (OLs) are phosphorus-free membrane lipids present in many bacteria, but absent from eukaryotes and archaea. Three pathways for OL synthesis have been reported to date. Conditions that induce OL synthesis include elevated temperature, low
David Moyano-Palazuelo +2 more
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Molbank, 2021 In the present work, construction of double-charged cationic amphiphilic 1,1′-{[3,5-bis(dodecyl¬oxy-carbonyl)-4-(thiophen-3-yl)-1,4-dihydropyridine-2,6-diyl]bis-(methylene)}bis(pyridin-1-ium) dibromide (7) was performed in four steps.
Martins Rucins +6 more
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Molbank, 2022 Synthesis of a double-charged cationic amphiphilic 1,4-dihydropyridine derivative with dodecyl ester groups at positions 3 and 5 of the 1,4-DHP ring was performed starting from Hantzsch type cyclization of dodecyl acetoacetate, 2-naphthaldehyde and ...
Martins Rucins +5 more
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Engineering cell free protein synthesis and synthetic cells [PDF]
, 2023 Mimicking the structure and function of natural cells, synthetic cells hold significant potential in various applications. These synthetic cells, which come in numerous forms, are developed from different materials, including lipids and proteins, as well
Chowdhry, Razia
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Somnogenic activities of synthetic lipid A [PDF]
Infection and Immunity, 1989 Bacterial infections and various immune response modifiers, including endotoxin and its lipid A moiety, alter sleep duration. The purpose of this study is to amplify our understanding of lipid A structure-somnogenic-pyrogenic activity relationships.
A B, Cady +4 more
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Lipid sponge droplets as programmable synthetic organelles [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance Organelles spatially and temporally orchestrate biochemical reactions in a cell to a degree of precision that is still unattainable in synthetic reaction systems. Additionally, organelles such as the endoplasmic reticulum (ER) contain highly interconnected and dense membrane networks that provide large reaction spaces for
Bhattacharya, Ahanjit +8 more
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Synthesis, self-assembly and lipoplex formulation of two novel cyclic phosphonate lipids [PDF]
QScience Connect, 2013 Background: Synthetic cationic lipids hold much potential as gene packaging and delivery agents for the treatment of inherited and acquired life threatening diseases, such as cancer, AIDS, cardiovascular diseases, and certain autoimmune disorders ...
JenniferYeh +4 more
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Synthesis of ether lipids: natural compounds and analogues
Beilstein Journal of Organic Chemistry, 2023 Ether lipids are compounds present in many living organisms including humans that feature an ether bond linkage at the sn-1 position of the glycerol. This class of lipids features singular structural roles and biological functions. Alkyl ether lipids and
Marco Antônio G. B. Gomes +7 more
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Bioactive Ether Lipids: Primordial Modulators of Cellular Signaling
Metabolites, 2021 The primacy of lipids as essential components of cellular membranes is conserved across taxonomic domains. In addition to this crucial role as a semi-permeable barrier, lipids are also increasingly recognized as important signaling molecules with diverse
Nikhil Rangholia +2 more
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