Results 31 to 40 of about 273,223 (309)
Nanocarrier lipid composition modulates the impact of pulmonary surfactant protein B (SP-B) on cellular delivery of siRNA [PDF]
, 2019 Two decades since the discovery of the RNA interference (RNAi) pathway, we are now witnessing the approval of the first RNAi-based treatments with small interfering RNA (siRNA) drugs. Nevertheless, the widespread use of siRNA is limited by various extra-
De Backer, Lynn +7 more
core +1 more source
Development of synthetic lung surfactants.
Journal of Lipid Research, 1988 We have previously reported the development of a reconstituted lung surfactant consisting of an organic solvent extract of natural bovine lung surfactant supplemented with synthetic lipids.
Y Tanaka +5 more
doaj +1 more source
Біофізичний вісник, 2020 Background: At lipid interfaces, water plays a crucial role in carrying biological processes, so that there is a huge interest in unravelling the behaviour of water close to membranes.
F. Cecchet
doaj +1 more source
The anti-tumor drug 2-hydroxyoleic acid regulates the oncogenic potassium channel Kv10.1
Beni-Suef University Journal of Basic and Applied Sciences, 2023 Background 2-hydroxyoleic acid (2OHOA) is a synthetic fatty acid with antitumor properties that alters membrane composition and structure, which in turn influences the functioning of membrane proteins and cell signaling. In this study, we propose a novel
Rita Morán-Zendejas +1 more
doaj +1 more source
Role of lipid transfer proteins in loading CD1 antigen-presenting molecules
Journal of Lipid Research, 2018 Research to connect lipids with immunology is growing, but details about the specific roles of lipid transfer proteins (LTPs) in antigen presentation remain unclear.
Luc Teyton
doaj +1 more source
Microbial Biotechnology, 2023 Microbial lipids for chemical synthesis are commonly obtained from sugar‐based substrates which in most cases is not economically viable. As a low‐cost carbon source, short‐chain fatty acids (SCFAs) that can be obtained from food wastes offer an ...
Sergio Morales‐Palomo +2 more
doaj +1 more source
Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine. [PDF]
, 2015 Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Brinker, C Jeffrey +3 more
core +2 more sources
Aminosugar-based immunomodulator lipid A: synthetic approaches [PDF]
Beilstein Journal of Organic Chemistry, 2018 The immediate immune response to infection by Gram-negative bacteria depends on the structure of a lipopolysaccharide (LPS, also known as endotoxin), a complex glycolipid constituting the outer leaflet of the bacterial outer membrane. Recognition of picomolar quantities of pathogenic LPS by the germ-line encoded Toll-like Receptor 4 (TLR4) complex ...
openaire +3 more sources
Rational Design of Lipid-Based Vectors for Advanced Therapeutic Vaccines
VaccinesRecent advancements in vaccine delivery systems have seen the utilization of various materials, including lipids, polymers, peptides, metals, and inorganic substances, for constructing non-viral vectors.
Yufei Ma, Yiang Chen, Zilu Li, Yu Zhao
doaj +1 more source
Effects of organic plant oils and role of oxidation on nutrient utilization in juvenile rainbow trout (Oncorhynchus mykiss) [PDF]
, 2012 The study compared the effect of four either fresh or force oxidized organic plant oils in diets for juvenile rainbow trout (Oncorhynchus mykiss) in which 47% of conventional LT fish meal protein was substituted by a mixture of 3 organic plant protein ...
A. Jokumsen +37 more
core +1 more source