Results 41 to 50 of about 136,463 (299)
Synthetic Lipid Nanoparticles Targeting Steroid Organs [PDF]
Lipidots are original nanoparticulate lipid delivery vectors for drugs and contrast agents made from materials generally regarded as safe. Here, we characterized the in vivo stability, biodistribution, and pharmacokinetics of lipidots.Lipidots 55 nm in diameter and coated with a phospholipid/poly(ethyleneglycol) surfactant shell were triply labeled ...
Juliette, Mérian +5 more
openaire +2 more sources
Background: At lipid interfaces, water plays a crucial role in carrying biological processes, so that there is a huge interest in unravelling the behaviour of water close to membranes.
F. Cecchet
doaj +1 more source
Chemical Synthesis of Cell Wall Constituents of Mycobacterium tuberculosis [PDF]
The pathogen Mycobacterium tuberculosis (Mtb), causing tuberculosis disease, features an extraordinary thick cell envelope, rich in Mtb-specific lipids, glycolipids, and glycans.
Mira Holzheimer +7 more
core +1 more source
Role of lipid transfer proteins in loading CD1 antigen-presenting molecules
Research to connect lipids with immunology is growing, but details about the specific roles of lipid transfer proteins (LTPs) in antigen presentation remain unclear.
Luc Teyton
doaj +1 more source
Nebulisation of synthetic lamellar lipids mitigates radiation-induced lung injury in a large animal model [PDF]
Methods to protect against radiation-induced lung injury (RILI) will facilitate the development of more effective radio-therapeutic protocols for lung cancer and may provide the means to protect the wider population in the event of a deliberate or ...
Smith, Sionagh +16 more
core +1 more source
Microbial lipids for chemical synthesis are commonly obtained from sugar‐based substrates which in most cases is not economically viable. As a low‐cost carbon source, short‐chain fatty acids (SCFAs) that can be obtained from food wastes offer an ...
Sergio Morales‐Palomo +2 more
doaj +1 more source
Pfas Fluidize Synthetic and Bacterial Lipid Monolayers Based on Hydrophobicity and Lipid Charge
Poly- and Perfluoroalkyl substances (PFASs) are pollutants of emerging concern that persist in nature and pose environmental health and safety risks. PFAS disrupt biological membranes resulting in cellular inhibition, but the mechanism of disruption and the role of lipid composition remain unclear.
Naumann, Aleksandra +3 more
openaire +4 more sources
Rational Design of Lipid-Based Vectors for Advanced Therapeutic Vaccines
Recent advancements in vaccine delivery systems have seen the utilization of various materials, including lipids, polymers, peptides, metals, and inorganic substances, for constructing non-viral vectors.
Yufei Ma, Yiang Chen, Zilu Li, Yu Zhao
doaj +1 more source
Carbohydrate mediated drug delivery: Synthesis and characterization of new lipid-conjugates
A new synthetic methodology for cationic glycolipids using p-aminophenyl-α-d-mannopyranoside (PAPM), p-aminophenyl-α-d-galactopyranoside (PAPG) was developed.
Moghis U. Ahmad +5 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source

