Results 41 to 50 of about 136,463 (299)

Synthetic Lipid Nanoparticles Targeting Steroid Organs [PDF]

open access: yesJournal of Nuclear Medicine, 2013
Lipidots are original nanoparticulate lipid delivery vectors for drugs and contrast agents made from materials generally regarded as safe. Here, we characterized the in vivo stability, biodistribution, and pharmacokinetics of lipidots.Lipidots 55 nm in diameter and coated with a phospholipid/poly(ethyleneglycol) surfactant shell were triply labeled ...
Juliette, Mérian   +5 more
openaire   +2 more sources

Interfacial water at synthetic and natural lipid bilayers probed by vibrational sum-frequency generation spectroscopy

open access: yesБіофізичний вісник, 2020
Background: At lipid interfaces, water plays a crucial role in carrying biological processes, so that there is a huge interest in unravelling the behaviour of water close to membranes.
F. Cecchet
doaj   +1 more source

Chemical Synthesis of Cell Wall Constituents of Mycobacterium tuberculosis [PDF]

open access: yes, 2021
The pathogen Mycobacterium tuberculosis (Mtb), causing tuberculosis disease, features an extraordinary thick cell envelope, rich in Mtb-specific lipids, glycolipids, and glycans.
Mira Holzheimer   +7 more
core   +1 more source

Role of lipid transfer proteins in loading CD1 antigen-presenting molecules

open access: yesJournal of Lipid Research, 2018
Research to connect lipids with immunology is growing, but details about the specific roles of lipid transfer proteins (LTPs) in antigen presentation remain unclear.
Luc Teyton
doaj   +1 more source

Nebulisation of synthetic lamellar lipids mitigates radiation-induced lung injury in a large animal model [PDF]

open access: yes, 2018
Methods to protect against radiation-induced lung injury (RILI) will facilitate the development of more effective radio-therapeutic protocols for lung cancer and may provide the means to protect the wider population in the event of a deliberate or ...
Smith, Sionagh   +16 more
core   +1 more source

Phosphate limitation as crucial factor to enhance yeast lipid production from short‐chain fatty acids

open access: yesMicrobial Biotechnology, 2023
Microbial lipids for chemical synthesis are commonly obtained from sugar‐based substrates which in most cases is not economically viable. As a low‐cost carbon source, short‐chain fatty acids (SCFAs) that can be obtained from food wastes offer an ...
Sergio Morales‐Palomo   +2 more
doaj   +1 more source

Pfas Fluidize Synthetic and Bacterial Lipid Monolayers Based on Hydrophobicity and Lipid Charge

open access: yesSSRN Electronic Journal, 2021
Poly- and Perfluoroalkyl substances (PFASs) are pollutants of emerging concern that persist in nature and pose environmental health and safety risks. PFAS disrupt biological membranes resulting in cellular inhibition, but the mechanism of disruption and the role of lipid composition remain unclear.
Naumann, Aleksandra   +3 more
openaire   +4 more sources

Rational Design of Lipid-Based Vectors for Advanced Therapeutic Vaccines

open access: yesVaccines
Recent advancements in vaccine delivery systems have seen the utilization of various materials, including lipids, polymers, peptides, metals, and inorganic substances, for constructing non-viral vectors.
Yufei Ma, Yiang Chen, Zilu Li, Yu Zhao
doaj   +1 more source

Carbohydrate mediated drug delivery: Synthesis and characterization of new lipid-conjugates

open access: yesData in Brief, 2015
A new synthetic methodology for cationic glycolipids using p-aminophenyl-α-d-mannopyranoside (PAPM), p-aminophenyl-α-d-galactopyranoside (PAPG) was developed.
Moghis U. Ahmad   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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