Results 61 to 70 of about 1,368,992 (302)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Cell-Free Phospholipid Biosynthesis by Gene-Encoded Enzymes Reconstituted in Liposomes. [PDF]
PLoS ONE, 2016 The goal of bottom-up synthetic biology culminates in the assembly of an entire cell from separate biological building blocks. One major challenge resides in the in vitro production and implementation of complex genetic and metabolic pathways that can ...
Andrew Scott +5 more
doaj +1 more source
Dynamics of lipids in synthetic membranes [PDF]
Pure and Applied Chemistry, 1994 Abstract
openaire +1 more source
Study of the miscibility of the hepatitis A synthetic antigen [L ys]113VP3110 with lipids
, 2001 The miscibility of the synthetic peptide antigen of hepatitis A, [Lys]113VP3110 with zwitterionic, anionic and cationic lipids was studied through compression isotherms of monolayers at the air/water interface.
M. Espina +4 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Identification of phosphatidylserylglutamate: a novel minor lipid in Escherichia coli
Journal of Lipid Research, 2009 Advances in mass spectrometry have facilitated the identification of novel lipid structures. In this work, we fractionated the lipids of Escherichia coli B and analyzed the fractions using negative-ion electrospray ionization mass spectrometry to reveal ...
Teresa A. Garrett +5 more
doaj +1 more source
Journal of Education, Health and Sport, 2022 Background. To determine the effect of consumption of high-oleic sunflower oil on the content and biosynthesis of energy and polyunsaturated (PUFA) fatty acids in rat liver lipids. Methods. Rats received a semi-synthetic fat-free diet in which 5 % or
A. Levitsky +4 more
doaj +1 more source
In Vitro Simultaneous Transfer of Lipids to HDL in Coronary Artery Disease and in Statin Treatment
, 2009 The exchange of lipids with cells and other lipoproteins is a crucial process in HDL metabolism and for HDL antiatherogenic function. Here, we tested a practical method to quantify the simultaneous transfer to HDL of phospholipids, free-cholesterol ...
Carolina H. Azevedo +13 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
BMC Biology, 2023 Background Many organisms rely on mineral nutrients taken directly from the soil or aquatic environment, and therefore, developed mechanisms to cope with the limitation of a given essential nutrient.
Stéphanie Bolik +7 more
doaj +1 more source