Results 61 to 70 of about 136,463 (299)

Reversible Optical Control of Monolayers on Water through Photoswitchable Lipids

, 2011
We have obtained molecular insights into a monolayer of azobenzene-based photoswitchable lipids self-assembled on water, using the surface sensitive technique vibrational sum-frequency generation spectroscopy in combination with surface pressure ...
Kuiper, Johanna, Poolman, Bert,, Kuiper, Johanna M.,, Engberts, Jan B.F.N., Mischa Bonn, Ellen H. G. Backus, Bonn, Mischa, Bert Poolman, Johanna M. Kuiper, Poolman, Bert, Jan B. F. N. Engberts, Engberts, Jan B.F.N.,, Bonn, Mischa,, Backus, Ellen H.G.,, Backus, Ellen H.G.   +14 more
core   +1 more source

Identification of phosphatidylserylglutamate: a novel minor lipid in Escherichia coli

Journal of Lipid Research, 2009
Advances in mass spectrometry have facilitated the identification of novel lipid structures. In this work, we fractionated the lipids of Escherichia coli B and analyzed the fractions using negative-ion electrospray ionization mass spectrometry to reveal ...
Teresa A. Garrett, Christian R.H. Raetz, Travis Richardson, Reza Kordestani, Jennifer D. Son, Rebecca L. Rose   +5 more
doaj   +1 more source

Influence of consumption of high oleic sunflower oil on the biosynthesis of fatty acids in the liver of rats

Journal of Education, Health and Sport, 2022
Background. To determine the effect of consumption of high-oleic sunflower oil on the content and biosynthesis of energy and polyunsaturated (PUFA) fatty acids in rat liver lipids. Methods. Rats received a semi-synthetic fat-free diet in which 5 % or
A. Levitsky, B. Egorov, A. Lapinskaya, I. Selivanskaya, V. Velichko   +4 more
doaj   +1 more source

CD14‐independent responses induced by a synthetic lipid A mimetic [PDF]

European Journal of Immunology, 2010
AbstractCRX‐527 belongs to a new family of synthetic lipid A mimetics, the aminoalkyl glucosaminide 4‐phosphates, which are considered as potential vaccine adjuvants or stand‐alone immunotherapeutics to harness innate immune defenses. Since natural lipid A from bacterial LPS depends on membrane‐bound (mCD14) or soluble CD14 for its TLR4 ligand activity,
Legat, Amandine, Thomas, Séverine, Hermand, Philippe, Van Mechelen, Marcelle, Goldman, Michel, De Wit, Dominique   +5 more
openaire   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Designer lipids for drug delivery: From heads to tails [PDF]

, 2014
For four decades, liposomes composed of both naturally occurring and synthetic lipids have been investigated as delivery vehicles for low molecular weight and macromolecular drugs.
Vincent J. Venditto, Venditto, Vincent J, Aditya G. Kohli, Colin L. Walsh, Walsh, Colin L, Francis C. Szoka, Paul H. Kierstead, Kierstead, Paul H, Szoka, Francis C, Kohli, Aditya G   +9 more
core   +1 more source

Lipid bilayer properties potentially contributed to the evolutionary disappearance of betaine lipids in seed plants

BMC Biology, 2023
Background Many organisms rely on mineral nutrients taken directly from the soil or aquatic environment, and therefore, developed mechanisms to cope with the limitation of a given essential nutrient.
Stéphanie Bolik, Alexander Schlaich, Tetiana Mukhina, Alberto Amato, Olivier Bastien, Emanuel Schneck, Bruno Demé, Juliette Jouhet   +7 more
doaj   +1 more source

A Synthetic Lipid A Mimetic Modulates Human TLR4 Activity [PDF]

ChemMedChem, 2011
Innate immunity recognition relies on a diverse set of germ line encoded receptors, termed pattern recognition receptors (PRR), which recognize broad classes of molecular structures common to groups of microorganisms. One of the largest and best studied families of PRR are the Toll family of receptors (Toll-like receptors, TLRs) that detect microbial ...
PERI, FRANCESCO, PIAZZA, MATTEO, Cighetti R, Damore G, CALABRESE, VALENTINA, Weiss J, Gioannini T.   +6 more
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Artificial Cells, Targeting Obesity, Proteases for Synthetic Biology, and Membrane Lipids in Action

, 2014
Each month, Chemistry & Biology Select highlights a selection of research reports from the recent literature. These highlights are a snapshot of interesting research done across the field of chemical biology.

core   +2 more sources