Results 61 to 70 of about 273,223 (309)

Lipid bilayer properties potentially contributed to the evolutionary disappearance of betaine lipids in seed plants

BMC Biology, 2023
Background Many organisms rely on mineral nutrients taken directly from the soil or aquatic environment, and therefore, developed mechanisms to cope with the limitation of a given essential nutrient.
Stéphanie Bolik, Alexander Schlaich, Tetiana Mukhina, Alberto Amato, Olivier Bastien, Emanuel Schneck, Bruno Demé, Juliette Jouhet   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Defining the Diffusion in Model Membranes Using Line Fluorescence Recovery after Photobleaching

Membranes, 2020
In this study, we explore the use of line FRAP to detect diffusion in synthetic lipid membranes. The study of the dynamics of these membrane lipids can, however, be challenging.
Jakob L. Kure, Camilla B. Andersen, Thomas E. Rasmussen, B. Christoffer Lagerholm, Eva C. Arnspang   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Protocol for building synthetic protocell membranes that sense redox using synthetic phospholipids and natural lipids

STAR Protocols
Summary: Sensing is a critical function of artificial cells; however, this is challenging to realize using bottom-up approaches. Here, we present a protocol for building protocell membranes that sense cues important for redox biochemistry and signaling ...
Liming Wang, Mark J. Dresel, Monique Robinson, Enver Cagri Izgu   +3 more
doaj   +1 more source

Genetically controlled membrane synthesis in liposomes

Nature Communications, 2020
Controlled membrane synthesis in liposomes is a prerequisite for synthetic systems emulating the fundamental properties of living cells. Here authors present that a de novo synthesized metabolic pathway converts precursors into a variety of lipids ...
Duco Blanken, David Foschepoth, Adriana Calaça Serrão, Christophe Danelon   +3 more
doaj   +1 more source

Lipid Ion Channels

, 2010
The interpretation electrical phenomena in biomembranes is usually based on the assumption that the experimentally found discrete ion conduction events are due to a particular class of proteins called ion channels while the lipid membrane is considered ...
Heimburg, Thomas
core   +1 more source

A minimal biochemical route towards de novo formation of synthetic phospholipid membranes. [PDF]

, 2019
All living cells consist of membrane compartments, which are mainly composed of phospholipids. Phospholipid synthesis is catalyzed by membrane-bound enzymes, which themselves require pre-existing membranes for function.
Bhattacharya, Ahanjit, Brea, Roberto J, Devaraj, Neal K, Niederholtmeyer, Henrike   +3 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Membrane lipids and their degradation compounds control GM2 catabolism at intralysosomal luminal vesicles

Journal of Lipid Research, 2019
The catabolism of ganglioside GM2 is dependent on three gene products. Mutations in any of these genes result in a different type of GM2 gangliosidosis (Tay-Sachs disease, Sandhoff disease, and the B1 and AB variants of GM2 gangliosidosis), with GM2 as ...
Susi Anheuser, Bernadette Breiden, Konrad Sandhoff   +2 more
doaj   +1 more source