Results 271 to 280 of about 273,223 (309)
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Calcium‐Responsive Liposomes via a Synthetic Lipid Switch
Chemistry – A European Journal, 2018AbstractLiposomal drug delivery would benefit from enhanced control over content release. Here, we report a novel avenue for triggering release driven by chemical composition using liposomes sensitized to calcium—a target chosen due to its key roles in biology and disease. To demonstrate this principle, we synthesized calcium‐responsive lipid switch 1,
Jinchao Lou +4 more
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Synthetic Lipid- and Lipoprotein Membranes
1971By superimposing monomolecular layers it is possible to arrange molecules in a specific planned order. This method of obtaining simple organized systems of molecules should be of interest to the membranologist as a possible means of building models of biological structures. The possibility of molecular contact between a synthetic monolayer assembly and
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[Lipid synthetic transcription factor, SREBP].
Nihon rinsho. Japanese journal of clinical medicine, 2005SREBP family have been recently established as bHLH type transcription factors governing lipid synthesis. While SREBP-2 regulates expression of genes involved in cholesterol biosynthesis and LDL receptor, SREBP-1c controls fatty acid synthesis. Cellular cholesterol is regulated by feedback system where SCAP/Insig system regulates cleavage of SREBP-2 ...
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Synthetic Lipid Bilayer Membranes
Annual Review of Biochemistry, 1969F A, Henn, T E, Thompson
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Anticancer activity of natural and synthetic acetylenic lipids
Lipids, 2006AbstractThis review is a comprehensive survey of acetylenic lipids and their derivatives, obtained from living organisms, that have anticancer activity. Acetylenic metabolites belong to a class of molecules containing triple bond(s). They are found in plants, fungi, microorganisms, and marine invertebrates.
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Synthetic erythrocytes from lipid encapsulated hemoglobin.
Experimental hematology, 1981Synthetic erythrocytes have been formed by encapsulating concentrated hemoglobin solutions in microcapsules consisting of phospholipid-cholesterol mixtures. The microcapsules (hemosomes) are of the order of one micron in diameter or smaller, are osmometers, are somewhat sturdier than erythrocytes (RBC), and are stable upon freezing.
L, Djordjevich, I F, Miller
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Synthetic and modified glycerides: effects on plasma lipids
Current Opinion in Lipidology, 2001It has been suggested that the molecular species or structure of the triglyceride, i.e. not only what fatty acids are present but also their relative order in the sn1, 2, or 3 position on the triglyceride, can influence the metabolism of the triglyceride and its fatty acids, including lipoprotein metabolism.
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Fusion of lipid bilayers induced by synthetic lipids and peptides
2009The fusion-inducing properties of three different synthetic lipid derivatives were investigated in model membranes. The results are discussed in terms of membrane destabilization caused by the formation of non-bilayer lipid structures following charge neutralization of the fusogenic components. First, studies on the fusion of large unilamellar vesicles
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Editorial overview: Synthetic biomolecules for probing lipid membranes
Current Opinion in Chemical Biology, 2023Neal K, Devaraj, Shinya, Tsukiji
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Engineering living therapeutics with synthetic biology
Nature Reviews Drug Discovery, 2021Andres Cubillos-Ruiz +2 more
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