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Controlled Fusion of Synthetic Lipid Membrane Vesicles
Accounts of Chemical Research, 2013Lipid membrane fusion is a fundamental noncovalent transformation as well as a central process in biology. The complex and highly controlled biological machinery of fusion has been the subject of intense investigation. In contrast, fewer synthetic approaches that demonstrate selective membrane fusion have been developed.
Mingming, Ma, Dennis, Bong
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The inhibition of lecithinase D activity by a synthetic lipid
Archives of Biochemistry and Biophysics, 1962Abstract The synthetic lecithin analog, 2,3-distearoyloxypropyl(dimethyl)-β-hydroxyethyl-ammonium acetate, was a powerful inhibitor of lecithin hydrolysis by Clostridium welchii lecithinase D. A continuous manual electrometric titration at pH 6.9–7.0 was employed.
A F, ROSENTHAL, R P, GEYER
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Synthetic Lipid- and Lipoprotein Membranes
1971By superimposing monomolecular layers it is possible to arrange molecules in a specific planned order. This method of obtaining simple organized systems of molecules should be of interest to the membranologist as a possible means of building models of biological structures. The possibility of molecular contact between a synthetic monolayer assembly and
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Fusion of lipid bilayers induced by synthetic lipids and peptides
2009The fusion-inducing properties of three different synthetic lipid derivatives were investigated in model membranes. The results are discussed in terms of membrane destabilization caused by the formation of non-bilayer lipid structures following charge neutralization of the fusogenic components. First, studies on the fusion of large unilamellar vesicles
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Bilayer-Forming Synthetic Lipids: Drugs or Carriers?
Current Medicinal Chemistry, 2003Since their introduction as bilayer-forming synthetic compounds in the eighties, dioctadecyldimethylammonium (DODA) and dihexadecylphosphate (DHP) salts have found many uses in strategic, applied areas. In particular, DODA chloride or bromide vesicles interacted with negatively charged prokaryotic or eukaryotic cells, yielding adsorption isotherms of ...
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Anticancer activity of natural and synthetic acetylenic lipids
Lipids, 2006AbstractThis review is a comprehensive survey of acetylenic lipids and their derivatives, obtained from living organisms, that have anticancer activity. Acetylenic metabolites belong to a class of molecules containing triple bond(s). They are found in plants, fungi, microorganisms, and marine invertebrates.
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Synthetic Lipid Bilayer Membranes
Annual Review of Biochemistry, 1969F A, Henn, T E, Thompson
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Synthetic and modified glycerides: effects on plasma lipids
Current Opinion in Lipidology, 2001It has been suggested that the molecular species or structure of the triglyceride, i.e. not only what fatty acids are present but also their relative order in the sn1, 2, or 3 position on the triglyceride, can influence the metabolism of the triglyceride and its fatty acids, including lipoprotein metabolism.
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EFFECT OF A SYNTHETIC TRIGLYCERIDE ON LIPID METABOLISM
The American Journal of Clinical Nutrition, 1956L W, KINSELL +3 more
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