Results 1 to 10 of about 911,338 (260)

Synthetic Methods of Phosphonopeptides. [PDF]

Molecules, 2020
Phosphonopeptides are phosphorus analogues of peptides and have been widely applied as enzyme inhibitors and antigens to induce catalytic antibodies. Phosphonopeptides generally contain one aminoalkylphosphonic acid residue and include phosphonopeptides with C-terminal aminoalkylphosphonic acids and phosphonopeptides with a phosphonamidate bond.
Xu J.
europepmc   +5 more sources

Synthetic Methods for the Preparation of Conformationally Restricted Analogues of Nicotine [PDF]

Molecules, 2021
In the context of naturally occurring nitrogen heterocycles, nicotine is a chiral alkaloid present in tobacco plants, which can target and stimulate nicotinic acetylcholine receptors (nAChRs), a class of ligand-gated ion channels commonly located ...
Biswajit Panda, Gianluigi Albano
doaj   +2 more sources

An Insight into the Medicinal Chemistry Perspective of Macrocyclic Derivatives with Antitumor Activity: A Systematic Review

Molecules, 2022
The profound pharmacological properties of macrocyclic compounds have led to their development as drugs. In conformationally pre-organized ring structures, the multiple functions and stereochemical complexity provided by the macrocycle result in high ...
Yan Liang, Ru Fang, Qiu Rao
doaj   +1 more source

Structural and Synthetic Aspects of Small Ring Oxa- and Aza-Heterocyclic Ring Systems as Antiviral Activities

Viruses, 2023
Antiviral properties of different oxa- and aza-heterocycles are identified and properly correlated with their structural features and discussed in this review article.
Sibasish Manna, Koushik Das, Sougata Santra, Emily V. Nosova, Grigory V. Zyryanov, Sandipan Halder   +5 more
doaj   +1 more source

The Inclusive Synthetic Control Method [PDF]

SSRN Electronic Journal, 2020
We introduce the inclusive synthetic control method (iSCM), a modification of synthetic control methods that includes units in the donor pool potentially affected, directly or indirectly, by an intervention. This method is ideal for situations where including treated units in the donor pool is essential or where donor units may experience spillover ...
Di Stefano, Roberta, Mellace, Giovanni
openaire   +3 more sources

Synthesis of 5-Fluoroaminobenzothiazoles

SynOpen, 2020
A series of 5-fluoro-2-(N-substituted)aminobenzothiazoles were synthesized by intramolecular cyclisation of the corresponding thioureas, which were prepared by treatment of 4-substituted 3-fluoroanilines with appropriate isothiocyanates.
Pooja Sharma, Gurdial Singh, Bhoomendra A. Bhongade, Malleshappa N. Noolvi, Andanappa K. Gadad   +4 more
doaj   +1 more source

Direct Syntheses of Diphenylmethanol Derivatives from Substituted Benzenes and CHCl3 through Friedel‐Crafts Alkylation and Post‐Synthetic Hydrolysis or Alcoholysis Catalyzed by Alumina

ChemistryOpen, 2022
The present study reports an innovative finding that alumina containing water or primary alcohol catalyzes the hydrolysis or alcoholysis, respectively, of the product formed through AlCl3‐mediated Friedel‐Crafts alkylation of methyl‐substituted benzenes ...
Guga Suri, Dr. Fengying Liang, Prof. Dr. Mixia Hu, Prof. Meiling Wang, Prof. Ren Bu, Xiaoying Zhang, Hui Wang, Wenyan Dong, Prof. Dr. Chaolu Eerdun, Prof. Dr. Akihiko Tsuda   +9 more
doaj   +1 more source

Exploring Short and Efficient Synthetic Routes Using Titanocene(III)-Catalyzed Reactions: Total Synthesis of Natural Meroterpenes with Trisubstituted Unsaturations

Molecules, 2022
The stereo- and regioselective total syntheses of OMe derivatives of the scarce bioactive meroterpenoids makassaric acid (1) and fascioquinol B (2) have been accomplished.
Jennifer Rosales, Gustavo Cabrera, José Justicia   +2 more
doaj   +1 more source

0D Perovskites: Unique Properties, Synthesis, and Their Applications

Advanced Science, 2021
0D perovskites have gained much attention in recent years due to their fascinating properties derived from their peculiar structure with isolated metal halide octahedra or metal halide clusters.
Siqi Sun, Min Lu, Xupeng Gao, Zhifeng Shi, Xue Bai, William W. Yu, Yu Zhang   +6 more
doaj   +1 more source

Recent Advances in C–H Functionalization of Pyrenes

Chemistry, 2023
In recent years, transition metal-catalyzed C–H activation and site-selective functionalization have been considered to be valuable synthetic tactics to functionalize organic compounds containing multiple C–H bonds.
Srinivasarao Arulananda Babu, Arup Dalal, Subhankar Bodak   +2 more
doaj   +1 more source