Results 51 to 60 of about 2,190,641 (322)

Microwave Multicomponent Synthesis

Molecules, 2009
In the manner that very important research is often performed by multidisciplinary research teams, the applications of multicomponent reactions involving the combination of multiple starting materials with different functional groups leading to the ...
Helmut M. Hügel
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Synthesis and Thermoelectric Properties of Copper Sulfides via Solution Phase Methods and Spark Plasma Sintering

Crystals, 2017
Large-scale Cu2S tetradecahedrons microcrystals and sheet-like Cu2S nanocrystals were synthesized by employing a hydrothermal synthesis (HS) method and wet chemistry method (WCM), respectively.
Yun-Qiao Tang, Zhen-Hua Ge, Jing Feng
doaj   +1 more source

Synthesis of the 1,5‐Benzothiazepane Scaffold – Established Methods and New Developments

ChemistryOpen, 2023
The 1,5‐benzothiazepane structure is an important heterocyclic moiety present in a variety of commercial drugs and pharmaceuticals. This privileged scaffold exhibits a diversity of biological activities, including antimicrobial, antibacterial, anti ...
Ulrike Ronse, Katarina Magdalenić, Prof. Dr. John Van Camp, Prof. Dr. Matthias D'hooghe   +3 more
doaj   +1 more source

Evaluating Local Community Methods in Networks

, 2007
We present a new benchmarking procedure that is unambiguous and specific to local community-finding methods, allowing one to compare the accuracy of various methods. We apply this to new and existing algorithms.
Danon L, Danon L, Fred A L, Hagberg A Schult D Swart P, James P Bagrow, Luo F, Milo R Kashtan N Itzkovitz S Newman M E J Alon U, Newman M E J   +7 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Palladium‐Catalyzed Gem‐Diborylalkylation of Silyl Enol Ethers and N‐Vinylacetamide via Diboryl Carbon‐Centered Radicals

Advanced Science
Herein, a palladium‐catalyzed coupling of gem‐iododiborylalkanes with electron‐rich olefins to access β,β‐diboryl ketones and aldehydes under mild conditions is reported. This method exhibits broad substrate scope and excellent functional group tolerance.
Xiao‐Yu Xie, Yi Wei, Xin‐Yi Chen, Ming Li, Kai Hong   +4 more
doaj   +1 more source

Métodos de preparação de lactonas de anel médio Methods for the preparation of medium ring lactones

Química Nova, 2007
There are several natural products bearing medium ring lactone moieties, which are those containing a ring size in the range of 8 to 11 members. This review intends to cover the last 10 years (1996-2005) of the literature concerning the synthesis of ...
Luiz S. Longo Junior, Fernanda I. Bombonato, Helena M. C. Ferraz   +2 more
doaj   +1 more source

The extinction law from photometric data: linear regression methods

, 2012
Context. The properties of dust grains, in particular their size distribution, are expected to differ from the interstellar medium to the high-density regions within molecular clouds.
Akritas, Alves, Bessell, C. J. Lada, Cambrésy, Chapman, Chapman, Draine, Flaherty, Fritz, Indebetouw, Isobe, J. Alves, J. Ascenso, Jones, Kenyon, Lombardi, Lutz, M. Lombardi, Martin, McClure, Nishiyama, Nishiyama, Ossenkopf, Rieke, Román-Zúñiga, Seares, Steinacker, Whittet, Whittet   +29 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source