Results 241 to 250 of about 811,099 (302)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Outcomes in hospitalised patients with penicillin allergy: a systematic review and meta-analysis protocol. [PDF]

Syst Rev
Davis E, Gill R, Reda E, Thomas E, Saba M, Chen H, Whitehouse T.   +6 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

AI-Enabled Smart Glasses for Active Aging: Scoping Review. [PDF]

JMIR Aging
Delgado-Morales C, García-Iglesias JJ, Duarte-Hueros A.   +2 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Evaluating the Efficacy and Efficiency of GPT-5 for Automated Title and Abstract Screening in Orthopedic Surgery Systematic Reviews. [PDF]

Curr Rev Musculoskelet Med
Vivekanantha P, Son H, Bernardini L, Bouchard MD, Ayeni OR, Kay J.   +5 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

AI-Assisted Systematic Review: Humans Still Need to Review All Abstracts for Inclusion. [PDF]

JMIR Form Res
Sung H, Altahsh D, Garrison S.
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Methods of Engaging Interest-Holders in Healthcare Evidence Syntheses: A Scoping Review. [PDF]

Cochrane Evid Synth Methods
Todhunter-Brown A, Petkovic J, Chang C, Griebler U, Hannigan A, Hilgart J, Hussain B, Jull J, Koscher-Kien C, Ledinger D, Nussbaumer-Streit B, Oloyede O, Tomlinson E, Dawson S, Dewidar O, Grant S, Lytvyn L, Concannon TW, Dans L, John D, Jordan Z, Mayo-Wilson E, McCutcheon C, Nonino F, Pollock D, April KT, Campbell P, Khabsa J, Magwood O, Welch V, Tugwell P.   +30 more
europepmc   +1 more source