Results 61 to 70 of about 3,434,192 (362)

The Systemic Inflammation Hypothesis: Towards a New Paradigm of Acute Decompensation and Multiorgan Failure in Cirrhosis.

Journal of Hepatology, 2020
Acute decompensation (AD) of cirrhosis is defined by the development of ascites, hepatic encephalopathy (HE) and/or variceal bleeding. Ascites is traditionally attributed to splanchnic arterial vasodilation and left-ventricular dysfunction, HE to ...
V. Arroyo, P. Angeli, R. Moreau, R. Jalan, J. Clària, J. Trebicka, Javier Fernández, T. Gustot, P. Caraceni, M. Bernardi   +9 more
semanticscholar   +1 more source

Role of adipose tissue as an endocrineorgan in systemic inflammation [PDF]

, 2014
Introduction The escalating public health problem represented by obesity has spurred multidisciplinary research into adipose tissue and importantly, the molecular biology of the adipocyte.
Kosicka, A.
core   +1 more source

Contribution of the galanin system to inflammation [PDF]

SpringerPlus, 2015
Neurogenic inflammatory components mediated by peptidergic sensory nerves have a crucial impact on the symptoms of inflammatory diseases. Galanin is a regulatory sensory neuropeptide, which was shown to attenuate neurogenic inflammation, but our current understanding about its endogenous targets, and physiologic importance is incomplete.
Kofler, Barbara, Brunner, Susanne, Koller, Andreas, Wiesmayr, Silke, Locker, Felix, Lang, Roland, Botz, Balint, Kemény, Àgnes, Helyes, Zsuzsanna   +8 more
openaire   +2 more sources

Inflammation in multiple system atrophy

Frontiers in Immunology, 2023
Misfolding protein aggregation inside or outside cells is the major pathological hallmark of several neurodegenerative diseases. Among proteinopathies are neurodegenerative diseases with atypical Parkinsonism and an accumulation of insoluble fibrillary alpha-synuclein (synucleinopathies) or hyperphosphorylated tau protein fragments (tauopathies).
Marta Leńska-Mieciek, Natalia Madetko-Alster, Piotr Alster, Leszek Królicki, Urszula Fiszer, Dariusz Koziorowski   +5 more
openaire   +3 more sources

Gut-derived systemic inflammation as a driver of depression in chronic liver disease.

Journal of Hepatology, 2021
Depression and chronic liver disease (CLD) are important causes of disability, morbidity and mortality worldwide and their prevalence continues to rise. The rate of depression in CLD is high compared to that of the general population and is comparable to
V. Kronsten, T. Tranah, C. Pariante, D. Shawcross   +3 more
semanticscholar   +1 more source

Obesity, inflammation and the immune system [PDF]

Proceedings of the Nutrition Society, 2012
Obesity shares with most chronic diseases the presence of an inflammatory component, which accounts for the development of metabolic disease and other associated health alterations. This inflammatory state is reflected in increased circulating levels of pro-inflammatory proteins, and it occurs not only in adults but also in adolescents and children ...
Pérez de Heredia, F., Gómez-Martínez, Sonia, Marcos, Ascensión   +2 more
openaire   +3 more sources

Unraveling the clinical significance and prognostic value of the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, systemic immune-inflammation index, systemic inflammation response index, and delta neutrophil index: An extensive literature review

Turkish Journal of Emergency Medicine
In the field of critical care medicine, substantial research efforts have focused on identifying high-risk patient groups. This research has led to the development of diverse diagnostic tools, ranging from basic biomarkers to complex indexes and ...
Mehmet Muzaffer Islam, M. O. Satıcı, S. Eroğlu   +2 more
semanticscholar   +1 more source

Oral Microbiome in Relation to Periodontitis Severity and Systemic Inflammation

International Journal of Molecular Sciences, 2021
Systemic inflammation induced by periodontitis is suggested to be the link between periodontitis and cardiovascular disease. The aim of this work was to explore the oral microbiome in periodontitis in relation to disease severity and systemic ...
A. Plachokova, S. Andreu-Sánchez, Marlies P Noz, Jingyuan Fu, N. Riksen   +4 more
semanticscholar   +1 more source

Human papillomavirus infection can alter the level of tumour stemness and T cell infiltration in patients with head and neck squamous cell carcinoma

Frontiers in Immunology, 2022
Head and neck squamous cell carcinoma (HNSCC) usually has a poor prognosis and is associated with a high mortality rate. Its etiology is mainly the result from long-term exposure to either alcohol, tobacco or human papillomavirus (HPV) infection or a ...
Lingzhang Meng, Lingzhang Meng, Heming Lu, Heming Lu, Yueyong Li, Jingjie Zhao, Siyuan He, Zechen Wang, Jiajia Shen, Huixian Huang, Huixian Huang, Jinru Xiao, Suren Rao Sooranna, Jian Song, Jian Song   +14 more
doaj   +1 more source

Inflammasomes in chronic liver disease: Hepatic injury, fibrosis progression and systemic inflammation

Journal of Hepatology
Summary Chronic liver disease leads to hepatocellular injury that triggers a pro-inflammatory state in several parenchymal and non-parenchymal hepatic cell types, ultimately resulting in liver fibrosis, cirrhosis, portal hypertension and liver failure ...
Vlad Taru, Gyongyi Szabo, W. Mehal, T. Reiberger   +3 more
semanticscholar   +1 more source