Results 71 to 80 of about 32,366 (248)

Clinical profile of juvenile idiopathic arthritis from a tertiary care hospital in Northern India

Indian Journal of Rheumatology, 2020
Background: Juvenile idiopathic arthritis (JIA) is the most common rheumatological disorder in children with wide variation in its clinical profile. Objective: The aim is to study the clinical, laboratory, radiological, and treatment profile of children ...
Arun Hegde, Suchi Acharya, Kavita Singh, Uday Bhanu Kovilapu   +3 more
doaj   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Treatment of adult-onset Still's disease: a review [PDF]

, 2014
Adult-onset Still's disease (AOSD) is a rare inflammatory disorder that has been recently classified as a polygenic autoinflammatory disorder. The former classification, based on the disease course, seems to be quite dated.
Gerfaud-Valentin, M., Henry, T., Jamilloux, Y., Seve, P.   +3 more
core   +3 more sources

Leflunomide in systemic onset juvenile idiopathic arthritis

Indian Pediatrics, 2012
Methotrexate, the mainstay of treatment in Juvenile idiopathic arthritis, might not be effective in a few patients of polyarticular and systemic onset juvenile idiopathic arthritis. Use of biologicals like TNF-a blockers, the next line of preferred drugs is constrained by the high cost. We successfully used leflunomide in four patients.
Afsana, Jahan, Vivek, Dewan, Tribhuvan Pal, Yadav   +2 more
openaire   +2 more sources

One year in review: ultrasound in arthritis [PDF]

, 2016
Musculoskeletal ultrasound (MSUS) has become a relevant part of rheumatology practice and research because it substantially allows us to optimize management of rheumatic and musculoskeletal diseases. This non-invasive imaging modality is a valuable point-
IAGNOCCO, Annamaria, Naredo, Esperanza
core  

Autoantibody Response Toward Chromatin in Patients With Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Patients with juvenile idiopathic arthritis (JIA) frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in patients with JIA remains elusive.
Viola Pitkänen, Terhi Remes‐Pakarinen, Paula Vähäsalo, Milja Möttönen, Minna‐Maija Grönlund, Miika Arvonen, Mikael Knip, Riitta Veijola, Jorma Toppari, Jorma Ilonen, Johanna Lempainen, Anna‐Mari Schroderus, Liisa Kröger, Tuure Kinnunen   +13 more
wiley   +1 more source

Treatment advances in systemic juvenile idiopathic arthritis [PDF]

F1000Prime Reports, 2014
Systemic juvenile idiopathic arthritis (JIA) is an autoinflammatory condition that is distinct from other forms of childhood arthritis. Recently, biologic agents that specifically inhibit the cytokines interleukin (IL)-1 and IL-6 have demonstrated remarkable clinical effectiveness and confirmed the importance of these cytokines in the disease process ...
openaire   +2 more sources

Initial manifestations and clinical course of systemic onset juvenile idiopathic arthritis: A ten-year retrospective study

Journal of the Formosan Medical Association, 2012
The diagnosis of systemic onset juvenile idiopathic arthritis (SoJIA) on disease onset is challenging and made mainly by exclusion. This study aimed to investigate the initial clinical and laboratory features of children with SoJIA in Taiwan.
Hu-Yuan Tsai, Jyh-Hong Lee, Hsin-Hui Yu, Li-Chieh Wang, Yao-Hsu Yang, Bor-Luen Chiang   +5 more
doaj   +1 more source

Serum Cytokine Profiling Differentiates Underlying Diseases in Cytokine Storm Syndrome

Arthritis &Rheumatology, EarlyView.
Serum cytokine profiling was performed using Luminex (48 cytokines) and ELISA (5 cytokines). Assessment of key cytokines (IFN‐α, IL‐18, IL‐6, CXCL9) delineated five dominant inflammatory patterns: I, IFN‐α–dominant CSS; II, IL‐18–dominant CSS; III, IL‐6–dominant CSS; IV, IFN‐γ–dominant CSS; and V, IL‐6 & IFN‐γ intermediate CSS.
Shuya Kaneko, Maho Hatano, Asami Shimbo, Futaba Miyaoka, Hitoshi Irabu, Yuko Akutsu, Yuko Hayashi, Mao Mizuta, Yasuo Nakagishi, Keiji Akamine, Naomi Iwata, Kenji Furuno, Takayuki Tanaka, Kazuyuki Ueno, Shuhei Fujita, Koji Yokoyama, Toshinori Minato, Kazushi Izawa, Takahiro Yasumi, Tadashi Matsubayashi, Tadashi Hosoya, Hiroki Nishikawa, Junya Fujimura, Ryoko Asano, Yuko Sugita, Kenichi Watanabe, Anna Kobayashi, Takuya Endo, Katsuhide Eguchi, Ryuta Nishikomori, Ryuhei Yasuoka, Takaki Asano, Miyako Kanno, Kazuya Hamada, Yuji Fujita, Daisuke Hayashi, Shojiro Watanabe, Takeshi Shiba, Shinsuke Yasuda, Masaaki Mori, Hirokazu Kanegane, Masatoshi Takagi, Masaki Shimizu   +42 more
wiley   +1 more source

Cytokine status and hemostasis disorders in children with juvenile idiopathic arthritis

Acta Biomedica Scientifica
Juvenile idiopathic arthritis is a chronic inflammatory joint disease in children under 16 years of age associated with pathological immune response to various antigens. Probable factors are infectious and immunogenetic.
M. V. Gomellya, A. V. Mironova, T. S. Krupskaya, A. V. Tatarinova   +3 more
doaj   +1 more source