Results 31 to 40 of about 1,282,511 (265)

How “benign” is cutaneous mastocytosis? A Danish registry-based matched cohort study

International Journal of Women's Dermatology, 2020
Background: There are limited estimates of the incidence rates (IRs) of mastocytosis, and only a few studies have addressed the long-term consequences of living with these diagnoses.
Line Kibsgaard, MD, PhD, Mette Deleuran, MD, Head of Department, Carsten Flohr, MD, Head of Department, Sinéad Langan, MD, Anne Braae Olesen, MD, PhD, Christian Vestergaard, MD, PhD   +5 more
doaj   +1 more source

Recalcitrant Cutaneous Mastocytosis Treated With Genetically Informed Targeted Therapy: A Case Report

International Journal of Dermatology and Venerology, 2023
Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease.
Laura Gleason, Volkan Tekmen, Alexa Cohen, Safiyyah Bhatti, Burcu Beksac, Jisun Cha, Pierluigi Porcu, Neda Nikbakht   +7 more
doaj   +1 more source

Clinical Outcomes of Adults with Systemic Mastocytosis: A 15-Year Multidisciplinary Experience

Cancers, 2022
Simple Summary The term mastocytosis denotes a heterogeneous group of rare disorders characterized by abnormal accumulation and activation of mast cells in various organs.
J. Ungerstedt, Christopher Ljung, Monika Klimkowska, Theo Gülen   +3 more
semanticscholar   +1 more source

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice

Haematologica, 2016
Systemic mastocytosis is a heterogeneous disease characterized by the accumulation of neoplastic mast cells in the bone marrow and other organ organs/tissues.
Celalettin Ustun, Michel Arock, Hanneke C. Kluin-Nelemans, Andreas Reiter, Wolfgang R. Sperr, Tracy George, Hans-Peter Horny, Karin Hartmann, Karl Sotlar, Gandhi Damaj, Olivier Hermine, Srdan Verstovsek, Dean D. Metcalfe, Jason Gotlib, Cem Akin, Peter Valent   +15 more
doaj   +1 more source

KITD816V+ systemic mastocytosis associated with KITD816V+ acute erythroid leukaemia: first case report with molecular evidence for same progenitor cell derivation [PDF]

, 2009
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
H-P Horny, K K Reichard, K Sotlar, M K Foucar, S A McClintock-Treep   +4 more
core   +1 more source

Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]

, 2008
We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
B. Przybilla, D. Fritze, Dubois AE, F. Ruëff, Fricker M, Ludolph-Hauser D, M. Hagedorn, N. Wagner, Reimers A, Rueff F   +9 more
core   +1 more source

The Number of MRGPRX2-Expressing Cells Is Increased in Skin Lesions of Patients With Indolent Systemic Mastocytosis, But Is Not Linked to Symptom Severity

Frontiers in Immunology, 2022
Background Recently, the expression of the mast cell (MC) receptor Mas-related G protein–coupled receptor X2 (MRGPRX2) has been detected in lesional skin of adult patients with cutaneous mastocytosis.
Polina Pyatilova, Tameem Ashry, Yanyan Luo, Jiajun He, H. Bonnekoh, Q. Jiao, S. Moñino-Romero, M. Hu, J. Scheffel, Stefan Frischbutter, M. Hermans, Bradford A. Youngblood, M. Maurer, F. Siebenhaar, P. Kolkhir   +14 more
semanticscholar   +1 more source

Systemic mastocytosis with associated myeloproliferative disease and precursor B lymphoblastic leukaemia with t(13;13)(q12;q22) involving FLT3. [PDF]

, 2008
Systemic mastocytoses represent neoplastic proliferations of mast cells. In about 20% of cases systemic mastocytoses are accompanied by clonal haematopoietic non-mast cell-lineage disorders, most commonly myeloid neoplasms.
Dirnhofer, S., Horny, H.-P., Jotterand, M., Muhlematter, D., Sotlar, Karl, Theocharides, A., Tzankov, A., Went, P.   +7 more
core   +1 more source

A Multidisciplinary Diagnostic Approach Reveals a Higher Prevalence of Indolent Systemic Mastocytosis: 15-Years’ Experience of the GISM Network

Cancers, 2021
Simple Summary The approach of the Interdisciplinary Group for Study of Mastocytosis (GISM) of Verona, based on a regional network of clinical specialists and expert pathologists, with the availability of sensitive molecular and flow-cytometry diagnostic
R. Zanotti, M. Bonifacio, Cecilia Isolan, I. Tanasi, L. Crosera, Francesco Olivieri, G. Orsolini, D. Schena, P. Bonadonna   +8 more
semanticscholar   +1 more source

A unique presentation of pulmonary disease in advanced systemic mastocytosis, proven by the presence of mast cells in bronchoalveolar lavage: A case report [PDF]

, 2016
Background: Systemic mastocytosis is a rare myeloproliferative disease characterized by the uncontrolled proliferation of aberrant mast cells. It has varying clinical manifestations.
Broijl, A. (Annemiek), Daele, P.L.A. (Paul) van, Hermans, M.A.W. (Maud A.W.)   +2 more
core   +2 more sources