Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
The effects of Thymus capitatus essential oil topical application on milk quality: a systems biology approach. [PDF]
Nehme R+20 more
europepmc +1 more source
Plastic based microfluidic systems and their applications in biology. [PDF]
Palaniappan Sethu
openalex
Apomixis inAchnanthes(Bacillariophyceae); development of a model system for diatom reproductive biology [PDF]
Koen Sabbe+3 more
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Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Systems biology of B cells in COVID-19. [PDF]
Woodruff MC, Faliti CE, Sanz I.
europepmc +1 more source
Application of the mouse exo utero development system in the study of developmental biology and teratology [PDF]
Toshihisa Hatta+2 more
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TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Systems Biology of Recombinant 2G12 and 353/11 mAb Production in CHO-K1 Cell Lines at Phosphoproteome Level. [PDF]
Sulaj E+5 more
europepmc +1 more source
High throughput instruments, methods, and informatics for systems biology.
Michael B. Sinclair+15 more
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