Results 231 to 240 of about 2,957,126 (345)

Systems biology modelling based evaluation of omega-3 formulation in managing cardiovascular and cerebrovascular risk. [PDF]

Sci Rep
Balakrishnan S, Saxena A, Mahapatra M, Damle A, Ramakrishnan S, Durairaj P, Kareenhalli V.   +6 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Advancing toxicity AI-based prediction with multilevel systems biology: a case study on genotoxicity. [PDF]

Brief Bioinform
Zhang X, Zhang H, Yun X, Pan W, Xue Q, Liu X, Fu J, Zhang A.   +7 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

A systems biology approach to identify key targets in KRAS/BRAF-mutated colorectal cancer. [PDF]

Discov Oncol
Shiravi S, Mottaghi-Dastjerdi N, Shahbazi B, Ahmadi N, Soltany-Rezaee-Rad M, Ghorbani A, Montazeri H.   +6 more
europepmc   +1 more source

Computational Methods in Systems Biology

, 2009
Pierpaolo Degano, Roberto Gorrieri
openalex   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Decoding the interplay between COVID-19 and diabetic nephropathy through bioinformatics and systems biology techniques. [PDF]

Biochem Biophys Rep
Chen X, Zeng Q, Xia M, Chen Y.
europepmc   +1 more source

Period - control in a coupled system of two genetic oscillators for synthetic biology

, 2019
Eleni Firippi, Madalena Chaves
openalex   +1 more source

A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI [PDF]

, 2013
Holger Husi, María Dolores Sánchez-Niño, Christian Delles, William Mullen, Antonia Vlahou, Alberto Ortíz, Harald Mischak   +6 more
openalex   +1 more source