Results 161 to 170 of about 320,373 (282)

Drug delivery and nanoparticles: Applications and hazards

International Journal of Nanomedicine, 2008
Wim H De Jong1, Paul JA Borm2,31Laboratory for Toxicology, Pathology and Genetics, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands; 2Zuyd University, Centre of Expertise in Life Sciences, Heerlen, The ...
Wim H De Jong, Paul JA Borm
doaj  

Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells. [PDF]

Toxicol Rep, 2020
Marescotti D, Mathis C, Belcastro V, Leroy P, Acali S, Martin F, Dulize R, Bornand D, Peric D, Guedj E, Ortega Torres L, Biasioli M, Fuhrimann M, Fernandes E, Frauendorfer F, Gonzalez Suarez I, Sciuscio D, Ivanov NV, Peitsch MC, Hoeng J.   +19 more
europepmc   +1 more source

Agricultural Injuries With Dementia: Double Whammy?

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Nearly 40% of US farmers are over 65 years old. Some emerging evidence links agricultural occupational exposure to increased dementia risk. However, little is known about dementia and injury outcomes in agricultural settings. Methods We employed data from the American College of Surgeons Trauma Quality Programs Participant Use File (
Kanika Arora, Jonathan Davis, Lila B. Basnet, Julie Bobitt   +3 more
wiley   +1 more source

Civilian Occupational Exposure to Vapors, Gas, Dust, or Fumes and Respiratory Health Among United States Military Veterans

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background We investigated associations of self‐reported and job exposure matrix (JEM) assigned civilian occupational exposure to vapors, gas, dust, or fumes (VGDF) with respiratory symptoms among previously deployed US Veterans. Methods An interviewer‐administered questionnaire ascertained self‐reported civilian occupational VGDF exposure.
Sahra Mohazzab‐Hosseinian, Carrie A. Redlich, Anna M. Korpak, Andrew K. I. Timmons, Nicholas L. Smith, Karen S. Nakayama, Farrah Kheradmand, Vincent S. Fan, Michael Jerrett, Philippe R. Montgrain, Christine H. Wendt, Ware G. Kuschner, Emily S. Wan, Eric Garshick, Paul D. Blanc   +14 more
wiley   +1 more source

Embracing Systems Toxicology at Single-Cell Resolution. [PDF]

Curr Opin Toxicol, 2019
Zhang Q, Caudle WM, Pi J, Bhattacharya S, Andersen ME, Kaminski NE, Conolly RB.   +6 more
europepmc   +1 more source

Comparison of the Hepatotoxic Potential of Two Treatments for Autosomal-Dominant Polycystic Kidney DiseaseUsing Quantitative Systems Toxicology Modeling. [PDF]

Pharm Res, 2020
Woodhead JL, Pellegrini L, Shoda LKM, Howell BA.   +3 more
europepmc   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Quantitative systems toxicology approach that integrates PBPK and core hepatic metabolism: a case study with valproic acid. [PDF]

Front Pharmacol
Gupta V, Jo H, Fisher CP, Kierzek AM.
europepmc   +1 more source

Public data sources to support systems toxicology applications. [PDF]

Curr Opin Toxicol, 2019
Davis AP, Wiegers J, Wiegers TC, Mattingly CJ.   +3 more
europepmc   +1 more source

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice. [PDF]

Toxicol Sci, 2020
Titz B, Sewer A, Luettich K, Wong ET, Guedj E, Nury C, Schneider T, Xiang Y, Trivedi K, Vuillaume G, Leroy P, Büttner A, Martin F, Ivanov NV, Vanscheeuwijck P, Hoeng J, Peitsch MC.   +16 more
europepmc   +1 more source