Results 221 to 230 of about 323,783 (333)

Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling. [PDF]

Pharm Res, 2019
Woodhead JL, Yang K, Oldach D, MacLauchlin C, Fernandes P, Watkins PB, Siler SQ, Howell BA.   +7 more
europepmc   +1 more source

Pharmacokinetics and Expert Systems as Aids for Risk Assessment in Reproductive Toxicology

, 1987
Donald R. Mattison, Frederick R. Jelovsek   +1 more
openalex   +1 more source

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang   +14 more
wiley   +1 more source

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology

, 2018
Blaine Phillips, Walter K. Schlage, Bjoern Titz, Ulrike Kogel, Davide Sciuscio, Florian Martin, Patrice Leroy, Grégory Vuillaume, Subash Krishnan, Tom Lee, Emilija Veljkovic, Ashraf Elamin, Céline Merg, Nikolai V. Ivanov, Manuel C. Peitsch, Julia Hoeng, Patrick Vanscheeuwijck   +16 more
openalex   +1 more source

Workshop on manpower development and training in toxicology and chemical safety. Luxembourg, 28 November - 2 December 1983. Industrial health and safety. EUR 9619 EN [PDF]

, 1984
Berlin, A., Smith, E., Tarkowski, S.
core  

An Intelligent Magneto‐Mechanical Platform for Cellular Sensing in 3D Microenvironments

Advanced Science, EarlyView.
This study presents MagMI, a pioneering machine intelligence‐driven magneto‐mechanical sensing platform. It utilizes magneto‐mechanical arrays and machine learning to achieve label‐free, real‐time monitoring and classification of cellular proliferation dynamics within 3D microenvironments.
Yue Quan, Yuxin Wang, Sen Ding, Bingpu Zhou, Yinning Zhou   +4 more
wiley   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Toxicological Patterns of Multicomponent Polymer Systems

, 2003
Rumyana Cherkezova, S. Racheva, A. Topliyska, S. Yu. Pavlov, Z. Zlatev   +4 more
openalex   +2 more sources

Advancing Risk Assessment through the Application of Systems Toxicology. [PDF]

Toxicol Res, 2016
Sauer JM, Kleensang A, Peitsch MC, Hayes AW.   +3 more
europepmc   +1 more source

Automatic analytical microflow systems for toxicological and pharmaceutical control

, 2012
David Sérgio de Moura Ribeiro
openalex   +2 more sources