Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Unraveling the Nrf2-ARE Signaling Pathway in the DF-1 Chicken Fibroblast Cell Line: Insights into T-2 Toxin-Induced Oxidative Stress Regulation. [PDF]
Toxins (Basel), 2023 Gao S +10 more
europepmc +1 more source
A review of artificial intelligence in brachytherapy
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen +4 more
wiley +1 more source
A biochemical, theoretical and immunohistochemical study comparing the therapeutic efficacy of curcumin and taurine on T-2 toxin induced hepatotoxicity in rats. [PDF]
Front Mol Biosci, 2023 Al-Zahrani MH +13 more
europepmc +1 more source
The cytotoxic effects of T-2 toxin on normal human lymphocytes. [PDF]
, 1998 Thesis (M.Med.)-University of Natal, Durban, 1998.T -2 toxin is an immunosuppressive mycotoxin that has been conjoined with several symptoms and diseases as early as the turn of the century, but whose mechanisms of action are still being investigated ...
Moodley, Therishnee.
core
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose Palliative radiotherapy comprises a significant portion of the radiation treatment workload. Volumetric‐modulated arc therapy (VMAT) improves dose conformity and, in conjunction with flattening filter free (FFF) delivery, can decrease treatment times, both of which are desirable in a population with a high probability of retreatment ...
Madeleine L. Van de Kleut +2 more
wiley +1 more source
Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks. [PDF]
Microorganisms, 2023 Stefanović D +10 more
europepmc +1 more source
A NEW METHOD FOR THE EVALUATION OF THE RESISTANCE OF MAIZE HYBRIDS TO FUSARIAL EAR ROT - THE TOXIN-MOULD-INDEX (TMI) [PDF]
, 1997 30 maize hybrids grown in Hungary representing the groups FAO 200 - 299, FAO 300 399, FAO 400 - 499, and FAO 500 - were studied in order to gain information about genotypic resistance to Fusarium moulds.
BATA, Árpád +3 more
core +1 more source
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose The study evaluates rapid linear accelerator (Linac) single isocenter stereotactic radiosurgery (SRS) with Hyperarc for large target numbers. We compared to Gamma Knife (GK), which suffers from long treatment times and investigated causes of differences. Methods Linac SRS and GK treatment plans for patients receiving 18 Gy to the gross
Abram Abdou +4 more
wiley +1 more source
Transformer-based toxin-protein interaction analysis prioritizes airborne particulate matter components with potential adverse health effects [PDF]
arXivAir pollution, particularly airborne particulate matter (PM), poses a significant threat to public health globally. It is crucial to comprehend the association between PM-associated toxic components and their cellular targets in humans to understand the mechanisms by which air pollution impacts health and to establish causal relationships between air ...
arxiv