Results 1 to 10 of about 30,760,761 (278)
New Approaches to Target T-ALL. [PDF]
Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Although it is now curable in 80-90% of cases, patients with T-ALL experience a higher frequency of induction failure and early relapse. Despite aggressive treatment approaches,
Giovanni eRoti +5 more
doaj +5 more sources
T-ALL and thymocytes: a message of noncoding RNAs
In the last decade, the role for noncoding RNAs in disease was clearly established, starting with microRNAs and later expanded towards long noncoding RNAs.
Annelynn Wallaert +4 more
doaj +4 more sources
EZH2 Knockdown Upregulates Expression of the Genes Involved in T-ALL Cell Differentiation [PDF]
Background: EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), as one of the polycyclic group proteins (PcGs), is an epigenetic regulator that plays a crucial role in the pathophysiology of hematologic malignancies through regulating cell ...
Sahar Safaei +10 more
doaj +1 more source
Review article: key aspects of mammal microbiome development
This review article summarizes current understanding of the microbiota development in neonatal mammals based on the results of modern experimental studies in animals focusing on three aspects: initial colonization, microbiota effect on the immune ...
E. V. Semenova +2 more
doaj +1 more source
Specific prevention is one of the most effective methods for the control of infectious diseases causing considerable economic damage to commercial pig farms, among which is porcine pleuropneumonia.
A. G. Shakhov +4 more
doaj +1 more source
A Novel Combination of Pterostilbene and Dexamethasone Enhances Anti-proliferation and Apoptosis Induction Properties in Lymphoblastic Leukemia Cell Line [PDF]
Background: T-cell acute lymphoblastic leukemia is an aggressive hematologic malignancy that results from the transformation of T-cell progenitors. Despite the significant advances in the current treatments, the side-effects of conventional chemotherapy ...
Zahra Sourani +3 more
doaj +1 more source
T-cell lymphoblastic leukaemia: The Johannesburg state-sector experience
Background: T-cell lymphoblastic leukaemia (T-ALL) is a malignancy of immature T-cells which is reported to comprise 7% – 23% of cases of lymphoblastic leukaemia (ALL), making up a larger proportion of adult ALL than childhood cases.
Jenifer Vaughan +3 more
doaj +1 more source
Method of restorating water level of small rivers [PDF]
The article presents method for restoring the water level of small rivers that are subjected to degradation on the example of section of the Meklet River.
Kuznetsov Evgeny +5 more
doaj +1 more source
Method of managing the agricultural resource potential of agrolandscapes [PDF]
The authors developed the methods of managing the agro-resource potential of agrolandscapes based on the risks of managing resource-adapted technologies.
Kuznetsov Evgeny +6 more
doaj +1 more source

