Results 81 to 90 of about 10,355,186 (284)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Frontiers in Immunology, 2020 Background: Interferon-gamma (IFN-γ) is a key mediator of sarcoidosis-related granulomatous inflammation. Previous findings of IFN-γ-producing Th17 cells in bronchoalveolar lavage fluid from sarcoidosis patients invokes the transition of Th17.0 cells to ...
Nicholas K. Arger +4 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells.
PLoS Pathogens, 2020 The two T-box transcription factors T-bet and Eomesodermin (Eomes) are important regulators of cytotoxic lymphocytes (CTLs), such as activated CD8 T cells, which are essential in the fight against intracellular pathogens and tumors.
Jonas Fixemer +10 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Lymphocytes isolated from the FRT and ILN were stimulated with PMA and ionomycin with Brefeldin A before staining for flow cytometry. Results are gated on CD4+ CD44hi cells.
Kevin D. Fong (17721439) +5 more
core +1 more source
Stability of the Bet v 1 cross-reactive allergens Api g 1 and Dau c 1 : a biophysical approach [PDF]
, 2009 The allergen Bet v 1 is known as the primary sensitizer for birch pollen-related food allergy and is responsible for IgE cross-reactivity to pathogenesis-related 10 (PR-10) proteins from, in particular, fruits from the Rosaceae and vegetables from the ...
Bollen, M.A.
core
T-bet and Eomes expression by responding HIV-specific CD8+ T cells over time.
, 2016 (A) Gag-specific CD8+ T cells (red) overlaid on perforin+ CD8+ T cells (black) from the acute (day 28) and chronic (day 434) infection time points of one donor. Percentages of responding Gag-specific cells within each T-bet and Eomes subset are provided.
Nilu Goonetilleke (208785) +18 more
core +1 more source
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment [PDF]
, 2000 Naive T helper cells differentiate into two subsets, Th1 and Th2, each with distinct functions and cytokine profiles. Here, we report the isolation of T-bet, a Th1-specific T box transcription factor that controls the expression of the hallmark Th1 ...
Susanne J Szabo +11 more
core +1 more source
The immune cell transcription factor T-bet [PDF]
Adipocyte, 2013 Obesity-associated insulin resistance is accompanied by an alteration in the Th1/Th2 balance in adipose tissue. T-bet (Tbx21) is an immune cell transcription factor originally described as the master regulator of Th1 cell development, although is now recognized to have a role in both the adaptive and innate immune systems.
Stolarczyk, Emilie +2 more
openaire +3 more sources