Results 61 to 70 of about 10,355,186 (284)

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager   +8 more
wiley   +1 more source

T-bet-deficiency affects Th17 plasticity to Th1-like ex Th17 cells in infected kidneys.

open access: yes, 2022
(A) UMAP dimensional reduction and (B) Cluster abundance of renal YFP+ CD4+ T cells 10 days after S. aureus infection of Il17aCre x R26eYFP x Tbx21-wildtype (cells pooled from n = 7 mice) and Il17aCre x R26eYFP x Tbx21-flox (cells pooled from n = 6 mice)
Victor G. Puelles (12239305)   +22 more
core   +1 more source

Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega   +10 more
wiley   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo   +11 more
wiley   +1 more source

T-bet binding at polymorphic sites.

open access: yes, 2017
A. Heat map showing T-bet occupancy around SNPs located within T-bet binding sites (T-bet hit-SNPs). Each row is centred on a single SNP, with T-bet binding shown across the genomic region stretching 2 kb up and downstream.
Stephen Henderson (372155)   +11 more
core   +1 more source

Transcription Factor Assay of Peripheral Blood T cells in Different Groups of Rheumatoid Arthritis Patients

open access: yesResearch in Molecular Medicine, 2020
Background: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints and other tissues and organs of the body.
Saeid Taghiloo   +6 more
doaj  

Higher Numbers of T-Bet+ Tumor-Infiltrating Lymphocytes Associate with Better Survival in Human Epithelial Ovarian Cancer

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: T-bet, a member of the T-box family of transcription factors, is a key marker of type I immune response within the tumor microenvironment, and has been previously reported by us to serve as an important prognostic indicator for human ...
Yun Xu   +9 more
doaj   +1 more source

T-bet terminates self-renewal [PDF]

open access: yesThe Journal of Experimental Medicine, 2007
A T cell transcription factor favors short-term benefits over long-term stability, according to a new study by Intlekofer et al. (page 2015). Figure 1 The transcription factor T-bet is expressed mainly in TEM cells. Long-term protection against pathogens by CD8+ T cells is due to a self-renewing population of central memory ...
openaire   +1 more source

FoxP3, GATA‐3 and T‐bet expression in elderly asthma [PDF]

open access: yesClinical & Experimental Allergy, 2010
Cite this as: S. Vale‐Pereira, A. Todo‐Bom, L. Geraldes, C. Schmidt‐Weber, C. A. Akdis and A. Mota‐Pinto, Clinical & Experimental Allergy, 2011 (41) 490–496.SummaryBackground Asthma is a chronic inflammatory disorder in which Th2, Th1 and suppressive T cells (Tregs) play a role.
Vale-Pereira, S   +5 more
openaire   +5 more sources

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens   +6 more
wiley   +1 more source

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