Results 51 to 60 of about 11,020,373 (290)
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
IMMUNOTHERAPEUTIC ACTION OF T-BET GENE MODIFIED DENDRITIC CELLS [PDF]
, 2013 T-bet is a Type-1 transcription factor that regulates the development of Type-1 T cell and Type-1 anti-tumor immunity. T-bet expression in Dendritic Cells (DC) is required for the ability of these antigen-presenting cells (APC) to prime Type-1-polarized ...
Chen, Lu
core
T-bet: a bridge between innate and adaptive immunity [PDF]
Nature Reviews Immunology, 2013 Originally described over a decade ago as a T cell transcription factor regulating T helper 1 cell lineage commitment, T-bet is now recognized as having an important role in many cells of the adaptive and innate immune system. T-bet has a fundamental role in coordinating type 1 immune responses by controlling a network of genetic programmes that ...
Lazarevic, Vanja +2 more
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source
T-bet and Eomes expression by responding HIV-specific CD8+ T cells over time.
, 2016 (A) Gag-specific CD8+ T cells (red) overlaid on perforin+ CD8+ T cells (black) from the acute (day 28) and chronic (day 434) infection time points of one donor. Percentages of responding Gag-specific cells within each T-bet and Eomes subset are provided.
Nilu Goonetilleke (208785) +18 more
core +1 more source
Clinical and Developmental Immunology, 2012 T-bet plays an important role in immunoregulation; it induces the differentiation of Th1 together with the homeobox transcription factor gene Hlx.
Yan Xu +12 more
doaj +1 more source
Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine +17 more
wiley +1 more source
T-bet and EOMES expression among antigen-inexperienced memory-phenotype αβ T cells, cell numbers.
, 2019 T-bet and EOMES expression among antigen-inexperienced memory-phenotype αβ T cells, cell numbers.
Andrew Getahun (314428) +7 more
core +1 more source
c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells
eLife, 2020 RORγt+ group 3 innate lymphoid cells (ILC3s) maintain intestinal homeostasis through secretion of type 3 cytokines such as interleukin (IL)−17 and IL-22.
Caroline Tizian +9 more
doaj +1 more source
T-bet + B Cells in Humans: Protective and Pathologic Functions. [PDF]
Transplantation, 2023 The humoral immune system comprises B cells and plasma cells, which play important roles in organ transplantation, ranging from the production of both protective and injurious antibodies as well as cytokines that can promote operational tolerance. Recent data from conditions outside of transplantation have identified a novel human B-cell subset that ...
Nellore A, Zumaquero E, Seifert M.
europepmc +3 more sources