Results 181 to 190 of about 14,321,563 (290)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Age-associated B cells, key players in autoimmune pathogenesis. [PDF]

Immun Ageing
Hassani SS, Ekrani ST, Rajabinejad M, Faraj TA, Rezaiemanesh A, Esmaeili SA.   +5 more
europepmc   +1 more source

Iterative Selection of DNA Nanostructures for Cellular Uptake

Advanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar, Lisa Eichhorn, Jakub Palacka, Sandra Ly, Erik Benson   +4 more
wiley   +1 more source

Lindera obtusiloba extract attenuates cytokine-mediated epidermal inflammation in keratinocytes and an MC903-induced AD-like mouse model. [PDF]

Sci Rep
Park SY, Joo Y, Kim SB, Kim M.
europepmc   +1 more source

Multimodal Engagement Assessment in Children During Invented Story Paradigm With a Social Robot

Advanced Robotics Research, EarlyView.
A multimodal framework is proposed to assess children's engagement during storytelling interactions with a social robot. Gaze, physiological, and behavioral data are combined and validated against observer ratings. An automated gaze‐labeling strategy is introduced, and supervised classifiers achieve high accuracy. The study supports scalable engagement
Laura Fiorini, Elena Adelucci, Stefano Scatigna, Lorenzo Pugi, Alice Bruni, Benedetta Carotenuto, Chiara Pecini, Filippo Cavallo   +7 more
wiley   +1 more source

BRD4: From molecular understanding to therapeutics development. [PDF]

Mol Cell
Wu SY, Chiang CM.
europepmc   +1 more source

Multimodal Human–Robot Interaction Using Human Pose Estimation and Local Large Language Models

Advanced Robotics Research, EarlyView.
A multimodal human–robot interaction framework integrates human pose estimation (HPE) and a large language model (LLM) for gesture‐ and voice‐based robot control. Speech‐to‐text (STT) enables voice command interpretation, while a safety‐aware arbitration mechanism prioritizes gesture input for rapid intervention.
Nasiru Aboki, Ilche Georgievski, Marco Aiello   +2 more
wiley   +1 more source

Shao-Ma-Zhi-Jing granules alleviate Tourette Syndrome by modulating the cAMP/PI3K/AKT/NF-κB signaling pathway, T cell differentiation, microglia, and gut microbiota. [PDF]

Front Physiol
Xue X, Luo LY, Wang J, Yang R, Ma XH, Wang GB, Song ZH, Li XX.   +7 more
europepmc   +1 more source

LLM‐Integrated Human–Robot Interaction System for Microrobots

Advanced Robotics Research, EarlyView.
This paper proposes an LLM‐based control framework for guiding microrobots using human natural language. This framework can convert the natural human speech into safe and executable command sets for reliable navigation in complex environments. The experimental results show high accuracy and robustness in task performance, demonstrating the potential of
Bairong Zhu, Amar Salehi, Tingting Yu
wiley   +1 more source

IL-27-Dependent <i>Lag3</i> Regulates CD4⁺ Foxp3⁺ Regulatory T Cells to Alleviate Airway Inflammation in Allergic Asthma. [PDF]

Int J Mol Sci
Zhu M, Feng R, Deng N, Chen Y, Yang J, Nie H.   +5 more
europepmc   +1 more source