Results 71 to 80 of about 14,413,699 (306)

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Quantifying T Cell Cross-Reactivity: Influenza and Coronaviruses

Viruses, 2021
If viral strains are sufficiently similar in their immunodominant epitopes, then populations of cross-reactive T cells may be boosted by exposure to one strain and provide protection against infection by another at a later date. This type of pre-existing
Jessica Ann Gaevert, Daniel Luque Duque, Grant Lythe, Carmen Molina-París, Paul Glyndwr Thomas   +4 more
doaj   +1 more source

Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy. [PDF]

, 2007
Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer ...
Burdach, S., Witter, K., Boerschmann Heike, Boerschmann, H., Mautner, Josef, Georg W Bornkamm, Adhikary, D., Adhikary, Dinesh, Uta Behrends, Burdach Stefan, Bornkamm, G.W., Mautner, J., Georg W, Andrea Pfünder, Moosmann, A., Witter Klaus, Adhikary Dinesh, Pfünder, Andrea, Dinesh Adhikary, Klaus Witter, Pfünder Andrea, Josef Mautner, Behrends Uta, Stefan Burdach, Moosmann Andreas, Andreas Moosmann, Bornkamm Georg W., Behrends, Uta, Boerschmann, Heike, Burdach, Stefan, Bornkamm, Georg W., Pfünder, A., Witter, Klaus, Behrends, U., Mautner Josef, Moosmann, Andreas, Heike Boerschmann   +36 more
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

The preferred substrates for transglutaminase 2 in a complex wheat gluten digest are Peptide fragments harboring celiac disease T-cell epitopes. [PDF]

PLoS ONE, 2010
BACKGROUND: Celiac disease is a T-cell mediated chronic inflammatory disorder of the gut that is induced by dietary exposure to gluten proteins. CD4+ T cells of the intestinal lesion recognize gluten peptides in the context of HLA-DQ2.5 or HLA-DQ8 and ...
Siri Dørum, Magnus Ø Arntzen, Shuo-Wang Qiao, Anders Holm, Christian J Koehler, Bernd Thiede, Ludvig M Sollid, Burkhard Fleckenstein   +7 more
doaj   +1 more source

Fluidity of HIV-1-specific T-cell responses during acute and early subtype C HIV-1 infection and associations with early disease progression. [PDF]

, 2010
Deciphering immune events during early stages of human immunodeficiency virus type 1 (HIV-1) infection is critical for understanding the course of disease.
Gray, Clive M, van Loggerenberg, Francois, Mlotshwa, Mandla., Loggerenberg, Francois van, Treurnicht, Florette K., Mlisana, Koleka Patience., Catherine Riou, Chopera, Denis, Mandla Mlotshwa, Denis Chopera, Gray, Clive M., Woodman, Zenda., CAPRISA 002 Study Team, Salim Abdool Karim, Mlisana, Koleka, Riou, Catherine, Abdool Karim, Salim Safurdeen., Ntale, Roman, Ntale, Roman., Williamson, Carolyn., Carolyn Williamson, Francois van Loggerenberg, Werner, Lise., Treunicht, Florette, Chopera, Denis Rutendo., Mlisana, Koleka P., Roman Ntale, de Assis Rosa, Debra, Debra de Assis Rosa, Woodman, Zenda, Zenda Woodman, Florette Treunicht, Williamson, Carolyn, Lise Werner, de Assis Rosa, Debra., Werner, Lise, Abdool Karim, Salim, Riou, Catherine., van Loggerenberg, Francois., Mlotshwa, Mandla, Koleka Mlisana, Chopera, Denis R., Assis Rosa, Debra de, Clive M. Gray   +43 more
core   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Multi-epitope vaccine design of African swine fever virus considering T cell and B cell immunogenicity

AMB Express
T and B cell activation are equally important in triggering and orchestrating adaptive host responses to design multi-epitope African swine fever virus (ASFV) vaccines.
Ting-Yu Chen, Yann-Jen Ho, Fang-Yu Ko, Pei-Yin Wu, Chia-Jung Chang, Shinn-Ying Ho   +5 more
doaj   +1 more source

Characterising the adaptive t-cell immune response against Kaposi’s sarcoma-associated herpesvirus [PDF]

, 2010
Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally related to Kaposi’s sarcoma (KS), the most common malignancy in individuals with untreated HIV/AIDS.
Robey, R.C.
core