Results 111 to 120 of about 2,668,255 (357)

Editor's evaluation: Robust T cell activation requires an eIF3-driven burst in T cell receptor translation

, 2021
Bernard Malissen
openalex   +1 more source

Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles. [PDF]

, 1996
The killer cell inhibitory receptors (KIRs) are surface glycoproteins expressed by natural killer (NK) and T cells that specifically recognize defined groups of polymorphic human histocompatibility leukocyte antigen (HLA) class I molecules.
Chang, C, D'Andrea, A, Lanier, LL, Phillips, JH   +3 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

TRain: T-cell receptor automated immunoinformatics

BMC Bioinformatics
Background The scarcity of available structural data makes characterizing the binding of T-cell receptors (TCRs) to peptide-Major Histocompatibility Complexes (pMHCs) very challenging.
Austin Seamann, Maia Bennett-Boehm, Ryan Ehrlich, Anna Gil, Liisa Selin, Dario Ghersi   +5 more
doaj   +1 more source

Neurohypophysial Receptor Gene Expression by Thymic T Cell Subsets and Thymic T Cell Lymphoma Cell Lines

Clinical and Developmental Immunology, 2004
Neurohypophysial oxytocin (OT) and vasopressin (VP) genes are transcribed in thymic epithelium, while immature T lymphocytes express functional neurohypophysial receptors.
I. Hansenne, G. Rasier, Ch. Charlet-renard, M.-P. Defresne, R. Greimers, C. Breton, J.-J. Legros, V. Geenen, H. Martens   +8 more
doaj   +1 more source

Transfer of the Interleukin-2 Gene Into Human Cancer Cells Induces Specific Antitumor Recognition and Restores the Expression of CD3/T-Cell Receptor Associated Signal Transduction Molecules [PDF]

, 1997
Anna Guarini, Ludovica Riera, Alessandro Cignetti, Laura Montacchini, Massimo Massaia, Robert Foà   +5 more
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Diminished Diversities and Clonally Expanded Sequences of T-Cell Receptors in Patients with Chronic Spontaneous Urticaria

ImmunoTargets and Therapy
Xian He,1,2 Xueping Wen,3 Peng Ming He,3 Dan Liang,2 Lihong Yang,2 Yuping Ran,1 Zhixin Zhang3 1Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Department of Allergy, Chengdu First People’s ...
He X, Wen X, He PM, Liang D, Yang L, Ran Y, Zhang Z   +6 more
doaj  

Sphingosine-1-phosphate receptor 2 restrains egress of γδ T cells from the skin. [PDF]

, 2019
Maintenance of a population of IL-17-committed γδ T cells in the dermis is important in promoting tissue immunity. However, the signals facilitating γδ T cell retention within the dermis remain poorly understood.
Cyster, Jason G, Gray, Elizabeth E, Laidlaw, Brian J, Ramírez-Valle, Francisco, Zhang, Yang   +4 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source