Results 181 to 190 of about 2,668,255 (357)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Correction to "Synthetic T-Cell Receptor-like Protein Behaves as a Janus Particle in Solution". [PDF]

J Am Chem Soc
Sakamoto-Rablah E, Bye J, Modak A, Hooker A, Uddin S, McManus JJ.   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

T-cell receptor clonotypic diversity and specialization in digestive system cancers. [PDF]

NPJ Precis Oncol
Li L, Li J, Wang F, Jiang R, Wang H, Li X, Zhen Y.   +6 more
europepmc   +1 more source

The T cell antigen receptor [PDF]

Biochemical Journal, 1985
M K, Collins, M J, Owen
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

TCRdb 2.0: an updated T-cell receptor sequence database. [PDF]

Nucleic Acids Res
Yue T, Chen SY, Shen WK, Liao Y, Lei Q, Guo AY.   +5 more
europepmc   +1 more source

1294 Engineering a T cell receptor (TCR) into an antibody drug format provides a novel approach to half-life extended T cell engagers targeting PRAME A2 and PRAME A24 [PDF]

Hemza Ghadbane, Dominic Hine, Patricia Cain, Louise Holland, Eleanor A. L. Bagg, Jana Rundle, Juan Bolivar, Xiaoyan Pan, Maria Busz, Samantha Drennan, David N. Cook, Sue Wells, Wilawan Bunjobpol, M. E. Marongiu, Mathew Veal, Samhita Rao, Maria Kokolaki, Alex Stephens, Daniel Burns, Amalia Martinez, Dzmitry G. Batrakou, Sophie Johnson, Oleksandr Dudchenko, Samuel R. Ward, Simon W. Wright, On Kan, Marjorie B. Lees, Graham S. Ogg, Nathaniel J. Davies, Thomas L. Andresen, Sarah Leonard   +30 more
openalex   +1 more source

193. Engineering CD20-Specific Chimeric Receptor-Redirected T Cells with Inducible Co-Expression of a Caspase-9 Based Suicide Switch for Adoptive Immunotherapy of CD20 Positive Lymphoma [PDF]

, 2012

openalex   +1 more source

Utilizing Remote Patient Monitoring to Safely Manage Chimeric Antigen Receptor T-Cell Recipients in the Outpatient Setting

, 2023
Trista Carelock, Kathryn Ashleigh Brooks, Brandie Haga, Rebecca Campo, Alma Flynn, Ms. Tonya Cox, Navneet S. Majhail   +6 more
openalex   +1 more source