Results 231 to 240 of about 2,668,255 (357)

The Human T-Cell Receptor

Annual Review of Immunology, 1984
Meuer, S, Acuto, O, Hercend, T, Schlossman, S, Reinherz, E   +4 more
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

T-cell receptor [PDF]

, 2011
openaire   +2 more sources

A T-cell receptor targeting RUNX1 frameshift mutations in acute myeloid leukemia. [PDF]

Leukemia
Struckman NE, Koutsoumpli G, de Jong RCM, van der Lee DI, Remst DFG, Smith SI, Honders MW, Hagedoorn RS, de Ru AH, Matsuda M, Ishikawa F, Tak T, Valk PJM, Heemskerk MHM, van Veelen PA, Falkenburg JHF, Griffioen M.   +16 more
europepmc   +1 more source

Different Activation States of Human Lymphocytes after Antibody‐Mediated Stimulation via CD3 and the α/β T‐Cell Receptor

, 1990
H. J. Schlitt, Reinhard Schwinzer, K. WONIGFIT   +2 more
openalex   +1 more source

Differences in the Symptom Experience and Quality of Life of Children and Adolescents Undergoing Hematopoietic Stem Cell Transplantation Compared to Chimeric Antigen Receptor T-Cell Therapy

, 2020
Jessica Ward, Paula Murray, Kimberly Powers, Jilayne Smith, Melody Hellsten   +4 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

T Cell Receptor Co-Stimulation Through Magnetogenetic Tools: A Platform for Wireless Rewiring of Cellular Signaling. [PDF]

ACS Omega
Helalat SH, Téllez RC, Thora Kristinsdóttir H, Dolinger Petersen A, Seder I, Rodriguez Pardo C, Sun Y.   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

TRAIT: A Comprehensive Database for T-cell Receptor-antigen Interactions. [PDF]

Genomics Proteomics Bioinformatics
Wei M, Wu J, Bai S, Zhou Y, Chen Y, Zhang X, Zhao W, Chi Y, Pan G, Zhu F, Chen S, Zhou Z.   +11 more
europepmc   +1 more source