Advanced Science, EarlyView.Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang +5 more
wiley +1 more source
Thyroid-Infiltrating T Lymphocyte Subsets in Hashimoto's Thyroiditis* [PDF]
, 1983 Rolf Jansson +3 more
openalex +1 more source
Phenotype and function of human T lymphocyte subsets: Consensus and issues
Cytometry Part A, 2008 V. Appay +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.PP1A dephosphorylates Keap1 at the S104 site, stabilizing and promoting the nuclear translocation of Nrf2, which upregulates the expression of antioxidant genes and PD‐L1. This leads to suppressed ferroptosis and enhanced immune evasion, thereby improving the efficacy of TKI and ICI combination therapy.
Jitong Zhou +10 more
wiley +1 more source
Changes in T lymphocyte subsets predict the efficacy of atezolizumab in advanced non-small cell lung cancer: a retrospective study. [PDF]
J Thorac Dis, 2023 Wang Y, Zhu J, Zhou N, Wang Y, Zhang X.
europepmc +1 more source
DON‐Loaded Nanodrug‐T Cell Conjugates With PD‐L1 Blockade for Solid Tumor Therapy
Advanced Science, EarlyView.This study establishes DON‐loaded T cell‐nanodrug conjugates with PD‐L1 blockade, creating a synergistic system. As a glutamine antagonist, sustained DON release enhances T‐cell endurance and infiltration by promoting memory differentiation and upregulating adhesion and motility genes, while PD‐L1 blockade alleviates immunosuppression and directs T ...
Xin Yang +13 more
wiley +1 more source
T Lymphocyte Subsets Profile and Toll-Like Receptors Responses in Patients with Herpes Zoster. [PDF]
J Pain Res, 2023 Chen W, Zhu L, Shen LL, Si SY, Liu JL.
europepmc +1 more source
Deficiency of the autologous mixed lymphocyte reaction in patients with classic hemophilia treated with commercial factor VIII concentrate. Correlation with T cell subset distribution, antibodies to lymphadenopathy-associated or human T lymphotropic virus, and analysis of the cellular basis of the deficiency. [PDF]
, 1985 Josef S Smolen +7 more
openalex +1 more source
Advanced Science, EarlyView.Y332D, a bispecific antibody that simultaneously blockades VEGF and TGF‐β, counteracted negative RT effects that are attributed to the upregulation of TGF‐β and VEGF, as well as further enhanced the immunostimulatory effects of RT, thereby reprograming the TME from immune “cold” to inflamed state and forming an effective in‐situ vaccine that eradicate ...
Lijuan Lyu +13 more
wiley +1 more source
Differential effect of cigarette smoking on recirculating T lymphocyte subsets in pregnant women. [PDF]
, 1986 Y C Smart +4 more
openalex +1 more source