In individuals with lymphedema, diabetic foot, or other diseases, infections with saprophytes are common. The response of major cell subpopulations in the draining lymph nodes to skin infection with Staphylococcus epidermidis was assessed using the rat ...
Marta Cąkała-Jakimowicz +1 more
doaj +1 more source
Shared determinants between virus-infected and trinitrophenyl-conjugated H-2-identical target cells detected in cell-mediated lympholysis [PDF]
Infection of H-2-identical mice with either lymphocytic choriomeningitis (LCM) virus, vaccinia virus, or paramyxo (Sendai) virus resulted in the generation of specifically sensitized cytotoxic T lymphocytes (CTL).
Bevan +16 more
core +1 more source
. Cytotoxic/pro-apoptogenic effects of IFNα-induced dendritic cells (IFN-DCs) directed against Т-lymphocytes and NK cells were investigated in healthy donors.
T. V. Tyrinova +5 more
doaj +1 more source
Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B and showing cross reactions with the natural proteins [PDF]
The human serine proteases granzymes A and B are expressed in cytotoplasmic granules of activated cytotoxic T lymphocytes and natural killer cells. Recombinant granzyme A and granzyme B proteins were produced in bacteria, purified and then used to raise ...
Borst, Jannie +9 more
core +9 more sources
miRNAs dictate relevant virus-host interactions, offering new avenues for interventions to achieve an HIV remission. We aimed to enhance HIV-specific cytotoxic responses—a hallmark of natural HIV control— by miRNA modulation in T cells.
Nadia Madrid-Elena +23 more
doaj +1 more source
HLA-Associated viral mutations are common in human immunodeficiency virus type 1 elite controllers [PDF]
Elite controllers (EC) of human immunodeficiency virus type 1 (HTV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8+ T lymphocytes are believed to play a crucial role in viral containment ...
Block, B. L. +10 more
core +2 more sources
Influence of the age and disease colorectal in immunity cutaneous pericolostomic [PDF]
Objective: describe the immunological response in the dermal layer of the peri-colostomic region. Method: Forty-one patients with colostomies realized over eight weeks previously, were included. For the analysis of the immunocellular response in the peri-
Franco, Marcello Fabiano de +4 more
core +4 more sources
Perforin, granzyme B, and FasL expression by peripheral blood T lymphocytes in emphysema
Background It is generally accepted that emphysematous lungs are characterized by an increase in the numbers of neutrophils, macrophages, and CD8+ T lymphocytes, the lasts having increased cytotoxic activity.
Parent Julie +2 more
doaj +1 more source
Natural Killer cells responsiveness to physical esercise: a brief review [PDF]
Natural killer cells (NK) are a group of peripheral blood lymphocytes which display cytotoxic ac- tivity against a wide range of tumour cells. They are a consistent part of the inflammatory re- sponse that is activated when either internal or external ...
Concu A. +4 more
core +1 more source
Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma [PDF]
Immune surveillance by cytotoxic lymphocytes against cancer has been postulated for decades, but direct evidence for the role of cytotoxic lymphocytes in protecting against spontaneous malignancy has been lacking.
Godfrey, DI +5 more
core +2 more sources

