Results 21 to 30 of about 164,918 (277)

Influence of FK 506 (tacrolimus) on circulating CD4 ⁺ t cells expressing cd25 and cd45ra antigens in 19 patients with chronic progressive multiple sclerosis participating in an open label drug safety trial [PDF]

, 1994
We have taken the opportunity of a clinical trial of the potential efficacy and safety of FK 506 (tacrolimus) in chronic progressive multiple sclerosis (MS) to examine the influence of this potent new immunosuppressant on circulating T-lymphocytes in an ...
A. W. Thomson, Abu-Elmagd K., B. Eidelman, B. Lemster, Collett D, Eidelman B H., Ellison G W., Emry P., Fung J J., H. R. Rilo, Hafler D A., Hafler D A., Hauser S L., Hintzen R Q., Hofman F M., J. J. Fung, J. Woo, Japanese FK, K. Abu-Elmagd, Kino T., Kurtzke J F, L. L. Huang, Lebranchu Y., Lemster B., Lemster B., McCauley J., McMichael J., Mochizuki M., Mortimoto C, N. Johnson, P. B. Carroll, R. Russell-Hall, Rose L M., Starzl T E., T. E. Starzl, Tamura K., The Multiple Sclerosis Study Group, Thomson A V., Thomson A W, Thomson A W., Thomson A W., Thomson A W., Tocci M J., W. Irish, Woo J., Woo J., Zeevi A.   +46 more
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Tertiary lymphoid organs in central nervous system autoimmunity [PDF]

, 2016
Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients.
Mitsdoerffer, M., Peters, A.
core   +1 more source

The specific features of cellular, humoral, and activation markers of the immune system and the biophysical parameters of superficial peripheral lymphocyte membranes in patients with breast cancer

Опухоли женской репродуктивной системы, 2014
The specific features of cellular and humoral factors of the immune system, as well as lymphocyte activation markers were studied in patients with breast cancer (BC). The biophysical parameters of superficial peripheral lymphocyte membranes were analyzed
L. T. Alimkhodzhayeva, A. D. Zikiryakhodzhayev   +1 more
doaj   +1 more source

Long-term study of the impact of methotrexate on serum cytokines and lymphocyte subsets in patients with active rheumatoid arthritis: correlation with pharmacokinetic measures [PDF]

, 2016
Objective To describe changes in immune parameters observed during long-term methotrexate (MTX) therapy in patients with active rheumatoid arthritis (RA) and explore correlations with simultaneously measured MTX pharmacokinetic (PKC) parameters ...
Hamilton, Robert, Kremer, Joel M., Lawrence, David A., McInnes, Iain B.   +3 more
core   +1 more source

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease activity [PDF]

, 2017
Background: Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation.
A Bhattacharya, AG Tzioufas, Annacarla Finucci, Antonina Minniti, Aroldo Rizzo, C Alessandri, C Li, C Vitali, C Vitali, CQ Nguyen, Cristiana Barbati, Cristiano Alessandri, D Geem, DJ Klionsky, DM Chisholm, E Astorri, Elena Ortona, Elisa Astorri, F Barone, F Ciccia, F Ciccia, F Ciccia, F Ciccia, F Sallusto, Fabrizio Conti, Francesco Ciccia, Giovanni Triolo, Giuliana Guggino, Guido Valesini, H Nakatogawa, HH Pua, HH Pua, HH Pua, I Tanida, LM Gerland, M Bombardieri, M Bombardieri, M Morgan-Bathke, M Morgan-Bathke, M Moriyama, M Pierdominici, Marina Pierdominici, Marta Vomero, Monica Pendolino, N Mizushima, N Schmitt, R Seror, Riccardo Alessandro, Roberta Priori, S Katsiougiannis, S Romao, Tania Colasanti, TC Adamson 3rd, W Jia, Walter Malorni, XJ Zhou, Y Seo, YZ Gong, Z Yang   +58 more
core   +3 more sources

NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice [PDF]

, 2018
Innate lymphoid cells (ILCs) producing IL-22 and/or IL-17, designated as ILC3, comprise a heterogeneous subset of cells involved in regulation of gut barrier homeostasis and inflammation.
Kanno, Yuka, Mikami, Yohei, O'Shea, John J, Santoni, Angela, SCARNO, GIANLUCA, Sciumè, Giuseppe, Shih, Han-Yu, Zitti, Beatrice   +7 more
core   +1 more source

Features of subset composition and functional activity of blood lymphocytes in tick-borne infections of different etiologies

Бюллетень сибирской медицины
Aim. To perform a comparative assessment of subset composition and functional activity of peripheral blood lymphocytes in patients with tick-borne encephalitis (TBE) and ixodid tick-borne borreliosis (ITBB) in the acute phase of the disease.Materials and
O. V. Voronkova, E. N. Ilyinskikh, R. R. Hasanova, I. E. Esimova, K. V. Nevskaya, M. R. Karpova, N. A. Chernyshov, A. V. Yampolskaya, O. V. Yampolskaya   +8 more
doaj   +1 more source

The Pro-tumorigenic IL-33 Involved in Antitumor Immunity: A Yin and Yang Cytokine

Frontiers in Immunology, 2018
Interleukin-33 (IL-33), considered as an alarmin released upon tissue stress or damage, is a member of the IL-1 family and binds the ST2 receptor. First described as a potent initiator of type 2 immune responses through the activation of T helper 2 (TH2)
Jean-Jacques Fournié, Mary Poupot
doaj   +1 more source

Antigen-specific electrophoretic cell separation for immunological investigations [PDF]

, 1989
Preincubation of human blood lymphocytes with cell surface antigen specific antibodies under non-capping conditions reduces the electrophoretic mobility of the corresponding lymphocyte subpopulation.
Hannig, K., Hansen, Ernil, Wustrow, T. P.   +2 more
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Heme Oxygenase-1 Restores Impaired GARP+CD4+CD25+ Regulatory T Cells from Patients with Acute Coronary Syndrome by Upregulating LAP and GARP Expression on Activated T Lymphocytes

Cellular Physiology and Biochemistry, 2015
Background: Accumulating evidence shows that the pathological autoreactive immune response is responsible for plaque rupture and the subsequent onset of acute coronary syndrome (ACS).
Yuzhou Liu, Xiaoqi Zhao, Yucheng Zhong, Kai Meng, Kunwu Yu, Huairui Shi, Bangwei Wu, Hasahya Tony, Jianghao Zhu, Ruirui Zhu, Yudong Peng, Yi Mao, Peng Cheng, Xiaobo Mao, Qiutang Zeng   +14 more
doaj   +1 more source