Results 1 to 10 of about 2,121,450 (262)

TAMRA-polypyrrole for A/T sequence visualization on DNA molecules. [PDF]

Nucleic Acids Res, 2018
Fluorophore-linked, sequence-specific DNA binding reagents can visualize sequence information on a large DNA molecule. In this paper, we synthesized newly designed TAMRA-linked polypyrrole to visualize adenine and thymine base pairs. A fluorescent image of the stained DNA molecule generates an intensity profile based on A/T frequency, revealing a ...
Lee S, Kawamoto Y, Vaijayanthi T, Park J, Bae J, Kim-Ha J, Sugiyama H, Jo K.   +7 more
europepmc   +4 more sources

On T-sequences and characterized subgroups

Topology and its Applications, 2010
Let $X$ be a compact metrizable abelian group and $\mathbf{u}=\{u_n\}$ be a sequence in its dual $X^{\wedge}$. Set $s_{\mathbf{u}} (X)= \{x: (u_n,x)\to 1\}$ and $\mathbb{T}_0^H = \{(z_n)\in \mathbb{T}^{\infty} : z_n\to 1 \}$. Let $G$ be a subgroup of $X$.
  +10 more sources

Retrieval Study of Brown Dwarfs across the L-T Sequence [PDF]

The Astrophysical Journal, 2022
Abstract A large suite of 228 atmospheric retrievals is performed on a curated sample of 19 brown dwarfs spanning the L0–T8 spectral types using the open-source Helios-r2 retrieval code, which implements the method of short characteristics for radiative transfer and a finite-element description of the temperature–pressure profile ...
Lueber, Anna, Kitzmann, Daniel, Bowler, Brendan P., Burgasser, Adam J., Heng, Kevin   +4 more
openaire   +4 more sources

A study of the complexification process of the (s,t)-Perrin sequence [PDF]

Notes on Number Theory and Discrete Mathematics, 2023
The present article deals with the study of the generalized (s,t)-Perrin sequence in its complex process. Thus, from the one-dimensional model of the generalized (s,t)-Perrin sequence, imaginary units are inserted, starting with the insertion of unit i ...
Renata Passos Machado Vieira, Francisco Regis Vieira Alves, Paula Maria Machado Cruz Catarino   +2 more
doaj   +1 more source

Solutions of nonlinear difference equations in the domain of ( ζ n ) $(\zeta _{n})$ -Cesàro matrix in ℓ t ( ⋅ ) $\ell _{t(\cdot)}$ of nonabsolute type, and its pre-quasi ideal

Journal of Inequalities and Applications, 2021
We have constructed the sequence space ( Ξ ( ζ , t ) ) υ $(\Xi (\zeta ,t) )_{\upsilon }$ , where ζ = ( ζ l ) $\zeta =(\zeta _{l})$ is a strictly increasing sequence of positive reals tending to infinity and t = ( t l ) $t=(t_{l})$ is a sequence of ...
Awad A. Bakery, Mustafa M. Mohammed
doaj   +1 more source

Location of troponin I‐binding on troponin T sequence [PDF]

FEBS Letters, 1982
Interaction between troponin T and troponin I is considered as one of those necessary for the calI cium-regulatory mechanism in the thin filament of vertebrate striated muscles [ 1,2]. Studies using chymotryptic subfragments of troponin T showed that the affinity for troponin I is localized in the region of the C-terminal 101 residues, termed troponin ...
Tanokura, Masaru, Ohtsuki, Iwao
openaire   +2 more sources

T cell receptor sequence clustering and antigen specificity

Computational and Structural Biotechnology Journal, 2020
There has been increasing interest in the role of T cells and their involvement in cancer, autoimmune and infectious diseases. However, the nature of T cell receptor (TCR) epitope recognition at a repertoire level is not yet fully understood.
Milena Vujovic, Kristine Fredlund Degn, Frederikke Isa Marin, Anna-Lisa Schaap-Johansen, Benny Chain, Thomas Lars Andresen, Joseph Kaplinsky, Paolo Marcatili   +7 more
doaj   +1 more source

Probing T-cell response by sequence-based probabilistic modeling.

PLoS Computational Biology, 2021
With the increasing ability to use high-throughput next-generation sequencing to quantify the diversity of the human T cell receptor (TCR) repertoire, the ability to use TCR sequences to infer antigen-specificity could greatly aid potential diagnostics ...
Barbara Bravi, Vinod P Balachandran, Benjamin D Greenbaum, Aleksandra M Walczak, Thierry Mora, Rémi Monasson, Simona Cocco   +6 more
doaj   +1 more source

Treatment Settings and Outcomes with Regorafenib and Trifluridine/Tipiracil at Third-Line Treatment and beyond in Metastatic Colorectal Cancer: A Real-World Multicenter Retrospective Study

Current Oncology, 2023
Background: Patients with refractory mCRC rarely undergo third-line or subsequent treatment. This strategy could negatively impact their survival. In this setting, regorafenib (R) and trifluridine/tipiracil (T) are two key new treatment options with ...
Carlo Signorelli, Maria Alessandra Calegari, Michele Basso, Annunziato Anghelone, Jessica Lucchetti, Alessandro Minelli, Lorenzo Angotti, Ina Valeria Zurlo, Marta Schirripa, Mario Giovanni Chilelli, Cristina Morelli, Emanuela Dell’Aquila, Antonella Cosimati, Donatello Gemma, Marta Ribelli, Alessandra Emiliani, Domenico Cristiano Corsi, Giulia Arrivi, Federica Mazzuca, Federica Zoratto, Maria Grazia Morandi, Fiorenza Santamaria, Rosa Saltarelli, Enzo Maria Ruggeri   +23 more
doaj   +1 more source

Extended Upstream A-T Sequence Increases T7 Promoter Strength [PDF]

Journal of Biological Chemistry, 2005
Bacteriophage T7 promoters contain a consensus sequence from -17 to +6 relative to the transcription start site, +1. In addition, the strong class III promoters are characterized by an extended AT-rich region upstream of -17, which is often interrupted by one or more GC base pairs in the weaker class II promoters.
Guo-Qing, Tang, Rajiv P, Bandwar, Smita S, Patel   +2 more
openaire   +2 more sources