The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis. [PDF]
BackgroundTrypanosoma brucei gambiense is the causative agent of chronic Human African Trypanosomiasis or sleeping sickness, a disease endemic across often poor and rural areas of Western and Central Africa.
Andrew P Jackson +13 more
doaj +2 more sources
The T cell receptor sequence influences the likelihood of T cell memory formation
Summary: The amino acid sequence of the T cell receptor (TCR) varies between T cells of an individual’s immune system. Particular TCR residues nearly guarantee mucosal-associated invariant T (MAIT) and natural killer T (NKT) cell transcriptional fates ...
Kaitlyn A. Lagattuta +7 more
doaj +2 more sources
Characterized Subgroups of Topological Abelian Groups
A subgroup H of a topological abelian group X is said to be characterized by a sequence v = (vn) of characters of X if H = {x ∈ X : vn(x) → 0 in T}. We study the basic properties of characterized subgroups in the general setting, extending results known ...
Dikran Dikranjan +2 more
doaj +1 more source
Determinant and inverse of T-Sequence-Sylvester-Kac Matrix
The Sylvester-Kac matrix is also known as the Clement matrix The Sylvester-Kac matrix is widely used and applied both in processing, graphs and other fields. The Sylvester-Kac matrix developed in the paper is the T-Sequence-Sylvester-Kac matrix The calculation of the determinant, and inverse has always been a challenge for mathematicians to find.
Jeki Saputra +2 more
openaire +1 more source
Detection of Enriched T Cell Epitope Specificity in Full T Cell Receptor Sequence Repertoires
High-throughput T cell receptor (TCR) sequencing allows the characterization of an individual's TCR repertoire and directly queries their immune state. However, it remains a non-trivial task to couple these sequenced TCRs to their antigenic targets.
Sofie Gielis +20 more
doaj +1 more source
Water quality prediction is important for maintaining water stability and control in marine environments. However, water quality parameters are affected by complex environmental factors.Marine time series data exhibit distribution shift and ...
Dashe Li +4 more
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Molecular instability of the mitochondrial haplogroup T sequences at nucleotide positions 16292 and 16296 [PDF]
The mitochondrial haplogroup T, characterized by the nucleotide motif 16126C–16294T in the hypervariable segment I (HVS I), is one of the most frequent among Europeans. It has been shown that this haplogroup includes the only well‐resolved subgroup, T1, but that other HVS I sequences cannot be differentiated into subgroups due to possible homoplasies ...
B A, Malyarchuk, M V, Derenko
openaire +2 more sources
Multilocus sequence typing (MLST) for lineage assignment and high resolution diversity studies in Trypanosoma cruzi. [PDF]
BACKGROUND: Multilocus sequence typing (MLST) is a powerful and highly discriminatory method for analysing pathogen population structure and epidemiology. Trypanosoma cruzi, the protozoan agent of American trypanosomiasis (Chagas disease), has remarkable
Michael A. Miles +61 more
core +1 more source
Analysis of T-DNA/Host-Plant DNA Junction Sequences in Single-Copy Transgenic Barley Lines
Sequencing across the junction between an integrated transfer DNA (T-DNA) and a host plant genome provides two important pieces of information. The junctions themselves provide information regarding the proportion of T-DNA which has integrated into the ...
Joanne G. Bartlett +2 more
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Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences. [PDF]
CD8+ T cells are important for HIV-1 virus control, but are also a major contributing factor that drives HIV-1 virus sequence evolution. Although HIV-1 cytotoxic T cell (CTL) escape mutations are a common aspect during HIV-1 infection, less is known ...
Emily M Eriksson +8 more
doaj +1 more source

