Results 21 to 30 of about 23,474 (264)

Talimogene Laherparepvec: Moving From First-In-Class to Best-In-Class

open access: yesFrontiers in Molecular Biosciences, 2022
Talimogene laherparepvec (T-VEC) is a modified oncolytic herpes Simplex virus, type 1 (HSV-1) encoding granulocyte-macrophage colony stimulating factor (GM-CSF).
Howard L. Kaufman   +3 more
doaj   +1 more source

Asymptotic vectors of entire curves

open access: yesМатематичні Студії, 2021
We introduce a concept of asymptotic vector of an entire curve with linearly independent components and without common zeros and investigate a relationship between the asymptotic vectors and the Picard exceptional vectors. A non-zero vector $\vec{a}=(
Ya.I. Savchuk, A.I. Bandura
doaj   +1 more source

Observational study of talimogene laherparepvec use in the anti-PD-1 era for melanoma in the US (COSMUS-2)

open access: yesMelanoma Management, 2020
Aim: Talimogene laherparepvec (T-VEC) is an intralesional therapy for unresectable, metastatic melanoma. T-VEC real-world use in the context of anti-PD1-based therapy requires further characterization. Materials & methods: A retrospective review of T-VEC
James Sun   +13 more
doaj   +1 more source

Efficacy and safety of oncolytic viruses in advanced or metastatic cancer: a network meta-analysis

open access: yesVirology Journal, 2021
Background Oncolytic viruses (OVs) have shown prospects in advanced and metastatic cancer, and many clinical trials have been carried out. To compare OV therapies comprehensively and provide a categorized profile and ranking of efficacy and safety, a ...
Ruiyang Xie   +5 more
doaj   +1 more source

T-VEC: a tool for developing critical systems [PDF]

open access: yesProceedings of 11th Annual Conference on Computer Assurance. COMPASS '96, 2002
This paper describes the specification-based testing and analysis tools, and associated processes, that were used to develop and certify safety-critical avionics systems in an industrial organization. These tools comprise an integrated development environment supporting specification acquisition and analysis, requirement-based automatic test vector ...
M.R. Blackburn, R.D. Busser
openaire   +1 more source

Use of Talimogene Laherparepvec to Treat Cutaneous Squamous Cell Carcinoma in a Renal Transplant Patient

open access: yesCase Reports in Dermatology, 2023
A 66-year-old female with a history of two renal transplants due to recurrent thrombotic thrombocytopenic purpura presented to clinic with multiple lesions identified to be non-metastatic cutaneous squamous cell carcinoma (CSCC).
Max Miller   +3 more
doaj   +1 more source

The nonnegative weak solution of a degenerate parabolic equation with variable exponent growth order

open access: yesBoundary Value Problems, 2020
A degenerate parabolic equation of the form ( | v | β − 1 v ) t = div ( b ( x , t ) | ∇ v | p ( x , t ) − 2 ∇ v ) + ∇ g → ⋅ ∇ γ → ( v ) $$\bigl( \vert v \vert ^{\beta-1}v\bigr)_{t}= \operatorname{div} \bigl(b(x,t) \vert \nabla v \vert ^{p(x,t)-2}\nabla v
Huashui Zhan
doaj   +1 more source

Biodistribution, shedding, and transmissibility of the oncolytic virus talimogene laherparepvec in patients with melanomaResearch in context

open access: yesEBioMedicine, 2019
Background: Talimogene laherparepvec (T-VEC) is an intralesionally delivered, modified herpes simplex virus type-1 oncolytic immunotherapy. The biodistribution, shedding, and potential transmission of T-VEC was systematically evaluated during and after ...
Robert H.I. Andtbacka   +9 more
doaj   +1 more source

The Coulomb law in the pure gauge U(1) theory on a lattice [PDF]

open access: yes, 1997
We study the heavy charge potential in the Coulomb phase of pure gauge compact U(1) theory on the lattice. We calculate the static potential $V_W(T,{\vec R})$ from Wilson loops on a $16^3 \times 32$ lattice and compare with the predictions of lattice ...
A. H. Guth   +20 more
core   +2 more sources

Multidimensional extension of the generalized Chowla-Selberg formula [PDF]

open access: yes, 1997
After recalling the precise existence conditions of the zeta function of a pseudodifferential operator, and the concept of reflection formula, an exponentially convergent expression for the analytic continuation of a multidimensional inhomogeneous ...
Elizalde, E.
core   +2 more sources

Home - About - Disclaimer - Privacy