Results 31 to 40 of about 23,474 (264)
Frontiers in Oncology, 2020 Background: Mucosal melanomas including melanomas of the urogenital tract represent a rare type of melanoma characterized by low mutational burden and poor prognosis.
Anne Fröhlich +8 more
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Counterterms in semiclassical Horava-Lifshitz gravity [PDF]
, 2010 We analyze the semiclassical Ho\v{r}ava-Lifshitz gravity for quantum scalar fields in 3+1 dimensions. The renormalizability of the theory requires that the action of the scalar field contains terms with six spatial derivatives of the field, i.e.
C Charmousis +19 more
core +2 more sources
Melanoma Management, 2019 Aim: Talimogene laherparepvec (T-VEC) is an intralesional treatment for unresectable cutaneous, subcutaneous and nodal melanoma. COSMUS-1 was conducted to examine how T-VEC is used in US clinical practice.
Matthew C Perez +9 more
doaj +1 more source
593 Tumoral melanosis mimicking residual melanoma After T-VEC treatment
Regular and young investigator award abstracts, 2020 Background Talimogene laherparepvec (T-VEC) has become an increasingly popular treatment option for surgically non-resectable, recurrent melanoma based on its durable efficacy and safety profile. The complete response (CR) rate has been reported to be ~20% with a median of ~9 months to achieve it. [figure 1,2] Assessment of treatment response in those
Song Park +5 more
openaire +1 more source
Loss of GRB2 associated binding protein 1 in arteriosclerosis obliterans promotes host autophagy
Chinese Medical Journal, 2021 . Background:. Arteriosclerosis obliterans (ASO) is a major cause of adult limb loss worldwide. Autophagy of vascular endothelial cell (VEC) contributes to the ASO progression. However, the molecular mechanism that controls VEC autophagy remains unclear.
Meng Ye +10 more
doaj +1 more source
Diagrammatic approach to soft non-Abelian dynamics at high temperature [PDF]
, 1999 The dynamics of soft ($|\vec{p}|\sim g^2 T$) non-Abelian gauge fields at finite temperature is non-perturbative. The effective theory for the soft scale is determined by diagrams with external momenta $p_0\lsim g^2 T$, $|\vec{p}|\sim g^2 T$ and loop ...
Bodeker, Dietrich
core +4 more sources
OncoImmunology, 2019 Successful immunotherapy for melanoma depends on the recruitment of effector CD8+ T cells to the tumor microenvironment. Factors contributing to T cell regulation in melanoma have recently been recognized, including the stimulator of interferon genes ...
Praveen K. Bommareddy +3 more
doaj +1 more source
Oriented Chromatic Number of Cartesian Products Pm □ Pn and Cm □ Pn
Discussiones Mathematicae Graph Theory, 2022 We consider oriented chromatic number of Cartesian products of two paths Pm □ Pn and of Cartesian products of paths and cycles, Cm □ Pn. We say that the oriented graph G→\vec G is colored by an oriented graph H→\vec H if there is a homomorphism from G ...
Nenca Anna
doaj +1 more source
T-VEC for Cancer Therapy: Applications, Limitations, and Potentials
Highlights in Science, Engineering and Technology, 2022 Cancer is a great threat to human health, and immunotherapy has become an important means to treat cancer in recent years. Talimogene laherparepvec (T-VEC), as an oncolytic virus, is one of the immunotherapy for melanoma. This article explains its mechanism, and then summarizes its clinical applications, including the effects and safety of monotherapy ...
openaire +1 more source
Journal for ImmunoTherapy of Cancer, 2021 Background Talimogene laherparepvec (T-VEC), an oncolytic virus, was designed to selectively replicate in and lyse tumor cells, releasing tumor-derived antigen to stimulate a tumor-specific immune response.Methods In this phase II study in patients with ...
Dirk Schadendorf +10 more
doaj +1 more source