Results 41 to 50 of about 19,567,220 (299)
Frontiers in Oncology, 2020 Background: Mucosal melanomas including melanomas of the urogenital tract represent a rare type of melanoma characterized by low mutational burden and poor prognosis.
Anne Fröhlich +8 more
doaj +1 more source
technology after a virtual educational camp in children and adolescents with type 1 diabetes: Does time in range plateau over 1 year? [PDF]
, 2023 Education, especially when designed for sharing between centres, can maximize the benefits of new diabetes technology. In 2020, when closed-loop control (CLC) with the Control-IQ system was introduced in Italy, we organized a virtual educational camp ...
Andrea E. Scaramuzza +16 more
core +1 more source
Melanoma Management, 2019 Aim: Talimogene laherparepvec (T-VEC) is an intralesional treatment for unresectable cutaneous, subcutaneous and nodal melanoma. COSMUS-1 was conducted to examine how T-VEC is used in US clinical practice.
Matthew C Perez +9 more
doaj +1 more source
OncoImmunology, 2019 Successful immunotherapy for melanoma depends on the recruitment of effector CD8+ T cells to the tumor microenvironment. Factors contributing to T cell regulation in melanoma have recently been recognized, including the stimulator of interferon genes ...
Praveen K. Bommareddy +3 more
doaj +1 more source
Loss of GRB2 associated binding protein 1 in arteriosclerosis obliterans promotes host autophagy
Chinese Medical Journal, 2021 . Background:. Arteriosclerosis obliterans (ASO) is a major cause of adult limb loss worldwide. Autophagy of vascular endothelial cell (VEC) contributes to the ASO progression. However, the molecular mechanism that controls VEC autophagy remains unclear.
Meng Ye +10 more
doaj +1 more source
T-VEC for Cancer Therapy: Applications, Limitations, and Potentials
Highlights in Science, Engineering and Technology, 2022 Cancer is a great threat to human health, and immunotherapy has become an important means to treat cancer in recent years. Talimogene laherparepvec (T-VEC), as an oncolytic virus, is one of the immunotherapy for melanoma. This article explains its mechanism, and then summarizes its clinical applications, including the effects and safety of monotherapy ...
openaire +1 more source
Oriented Chromatic Number of Cartesian Products Pm □ Pn and Cm □ Pn
Discussiones Mathematicae Graph Theory, 2022 We consider oriented chromatic number of Cartesian products of two paths Pm □ Pn and of Cartesian products of paths and cycles, Cm □ Pn. We say that the oriented graph G→\vec G is colored by an oriented graph H→\vec H if there is a homomorphism from G ...
Nenca Anna
doaj +1 more source
VEC trans-endocytosis occurs between HUVECs expressing endogenous VEC and COS7 cells expressing VEC fusion proteins. [PDF]
, 2014 (A) Co-culture of COS7 cells expressing VEC-EGFP (COS7-VEC-EGFP) and HUVECs expressing TagRFP657 (HUVEC-TagRFP657). Lower images are higher magnification of the indicated area in upper images.
Michael Simons (322098) +4 more
core +1 more source
Table_1_Case report: Therapeutic potential of T-VEC in combination with MEK inhibitors in melanoma patients with NRAS mutation.docx [PDF]
, 2023 Mutations in the NRAS gene are common alterations in malignant melanoma. However, there are no specific treatment options approved for NRAS-mutated melanoma patients besides immune checkpoint inhibition.
Sonja C. S. Simon (14604446) +2 more
core +1 more source
Journal for ImmunoTherapy of Cancer, 2021 Background Talimogene laherparepvec (T-VEC), an oncolytic virus, was designed to selectively replicate in and lyse tumor cells, releasing tumor-derived antigen to stimulate a tumor-specific immune response.Methods In this phase II study in patients with ...
Dirk Schadendorf +10 more
doaj +1 more source