Repertoire, genealogy and genomic organization of cruzipain and homologous genes in Trypanosoma cruzi, T. cruzi-like and other trypanosome species. [PDF]
PLoS ONE, 2012 Trypanosoma cruzi, the agent of Chagas disease, is a complex of genetically diverse isolates highly phylogenetically related to T. cruzi-like species, Trypanosoma cruzi marinkellei and Trypanosoma dionisii, all sharing morphology of blood and culture ...
Luciana Lima +8 more
doaj +4 more sources
How to improve the early diagnosis of Trypanosoma cruzi infection: Relationship between validated conventional diagnosis and quantitative DNA amplification in congenitally infected children [PDF]
, 2013 BACKGROUND: According to the Chagas congenital transmission guides, the diagnosis of infants, born to Trypanosoma cruzi infected mothers, relies on the detection of parasites by INP micromethod, and/or the persistence of T. cruzi specific antibody titers
Bua, Jacqueline Elena +7 more
core +25 more sources
Trypanosoma cruzi infection in neotropical wild carnivores (Mammalia: Carnivora): at the top of the T. cruzi transmission chain. [PDF]
PLoS ONE, 2013 Little is known on the role played by Neotropical wild carnivores in the Trypanosoma cruzi transmission cycles. We investigated T. cruzi infection in wild carnivores from three sites in Brazil through parasitological and serological tests.
Fabiana Lopes Rocha +10 more
doaj +2 more sources
Polyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults. [PDF]
PLoS Neglected Tropical Diseases, 2013 BackgroundAdults with chronic Trypanosoma cruzi exhibit a poorly functional T cell compartment, characterized by monofunctional (IFN-γ-only secreting) parasite-specific T cells and increased levels of terminally differentiated T cells.
María C Albareda +11 more
doaj +5 more sources
Cardiomyocyte oxidants production may signal to T. cruzi intracellular development. [PDF]
PLoS Negl Trop Dis, 2017 Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, presents a variable clinical course, varying from asymptomatic to serious debilitating pathologies with cardiac, digestive or cardio-digestive impairment.
Dias PP +7 more
europepmc +2 more sources
Protective role of TRPV1+ nociceptive neurons communication to macrophages against T. cruzi infection in mice [PDF]
Brain, Behavior, & Immunity - HealthChagas’ disease is a life-threatening condition caused by Trypanosoma cruzi. Patients with chronic disease may develop gastrointestinal, neurological, or associated neuro-digestive dysfunctions. CNS invasion by T.
Sergio M. Borghi +11 more
doaj +2 more sources
Astrocyte Apoptosis and HIV Replication Are Modulated in Host Cells Coinfected with Trypanosoma cruzi [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 The protozoan Trypanosoma cruzi is the etiological agent of Chagas disease. In immunosuppressed individuals, as it occurs in the coinfection with human immunodeficiency virus (HIV), the central nervous system may be affected. In this regard, reactivation
Javier M. Urquiza +11 more
doaj +3 more sources
Editorial: Unravelling T. cruzi Biology. [PDF]
Front Cell Infect Microbiol, 2020 Taylor MC, Lander N, Yoshida N.
europepmc +2 more sources
PLoS Neglected Tropical Diseases, 2011 Trypanosoma cruzi is the causative agent of Chagas disease, which affects more than 9 million people in Latin America. We have generated a draft genome sequence of the TcI strain Sylvio X10/1 and compared it to the TcVI reference strain CL Brener to ...
Oscar Franzén +6 more
semanticscholar +3 more sources
A metapopulation model for sylvatic T. cruzi transmission with vector migration
Mathematical Biosciences and Engineering, 2013 This study presents a metapopulation model for the sylvatic transmission of Trypanosoma cruzi, the etiological agent of Chagas' disease, across multiple geographical regions and multiple overlapping host-vector transmission cycles.Classical qualitative ...
Britnee Crawford +1 more
doaj +2 more sources