Results 21 to 30 of about 12,032,280 (304)

Use of a Chagas Urine Nanoparticle Test (Chunap) to Correlate with Parasitemia Levels in T. cruzi/HIV Co-infected Patients

PLoS Neglected Tropical Diseases, 2016
Background Early diagnosis of reactivated Chagas disease in HIV patients could be lifesaving. In Latin America, the diagnosis is made by microscopical detection of the T. cruzi parasite in the blood; a diagnostic test that lacks sensitivity.
Yagahira E. Castro-Sesquen, R. Gilman, Carolina Mejía, D. Clark, Jeong Choi, Melissa Reimer-Mcatee, Rosario Castro, Edward Valencia-Ayala, Jorge Flores, N. Bowman, R. Castillo-Neyra, F. Torrico, L. Liotta, C. Bern, A. Luchini   +14 more
semanticscholar   +1 more source

The Ly49E receptor inhibits the immune control of acute Trypanosoma cruzi infection [PDF]

, 2016
The protozoan parasite Trypanosoma cruzi circulates in the blood upon infection and invades various cells. Parasites intensively multiply during the acute phase of infection and persist lifelong at low levels in tissues and blood during the chronic phase.
Almeida, Andrade, Antunez, Aune, Avilan, Bern, Cardillo, Carlier, Carnaud, Cesari, Collins, Culbertson, Dowling, Duthie, Duthie, Duthie, Filtjens, Fraser, Frosch, Gritz, Hanke, Keating, Lieke, Lieke, Mekkawy, Meyer Zum Buschenfelde, Mondino, Nagata, Nogueira, Pettengill, Pinazo, Rassi, Robertson, Rottenberg, Santana, Sardinha, Stevenaert, Taveirne, Torrico, Truyens, Truyens, Truyens, Une, Van Beneden, Van Beneden, Van Den Broeck, Van Den Broeck, Vassalli, Wen   +48 more
core   +2 more sources

NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production. [PDF]

PLoS Neglected Tropical Diseases, 2013
Trypanosoma cruzi (T. cruzi) is an intracellular protozoan parasite and the etiological agent of Chagas disease, a chronic infectious illness that affects millions of people worldwide. Although the role of TLR and Nod1 in the control of T.
Virginia M Gonçalves, Kely C Matteucci, Carina L Buzzo, Bruna H Miollo, Danny Ferrante, Ana C Torrecilhas, Mauricio M Rodrigues, Jose M Alvarez, Karina R Bortoluci   +8 more
doaj   +1 more source

Trypanosoma cruzi genetic diversity: impact on transmission cycles and Chagas disease

Memórias do Instituto Oswaldo Cruz, 2022
Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and genetic diversity, along with eco-epidemiological complexity. In order to facilitate communication among researchers aiming at the characterisation of biological and
B. Zingales, D. Bartholomeu
semanticscholar   +1 more source

Canine Trypanosoma cruzi infection in the Bolivian Chaco [PDF]

, 2018
A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo, Chuquisaca Department, n = 57 dogs; and ...
Bartoloni, Alessandro, Cancrini, Gabriella, Gabrielli, Simona, Gamboa, Herlan, Macchioni, Fabio, Rojas, Patricia, Rojo, David, Roselli, Mimmo, Spinicci, Michele, Totino, Valentina   +9 more
core   +2 more sources

Antibody Repertoires Identify β-Tubulin as a Host Protective Parasite Antigen in Mice Infected With Trypanosoma cruzi

Frontiers in Immunology, 2018
Few studies investigate the major protein antigens targeted by the antibody diversity of infected mice with Trypanosoma cruzi. To detect global IgG antibody specificities, sera from infected mice were immunoblotted against whole T. cruzi extracts.
Fabricio Montalvão, Fabricio Montalvão, Danielle Oliveira Nascimento, Marise P. Nunes, Carolina M. Koeller, Alexandre Morrot, Alexandre Morrot, Leticia Miranda S. Lery, Paulo M. Bisch, Santuza M. R. Teixeira, Rita Vasconcellos, Leonardo Freire-de-Lima, Marcela F. Lopes, Norton Heise, George A. DosReis, Célio Geraldo Freire-de-Lima   +15 more
doaj   +1 more source

Different serological cross-reactivity of Trypanosoma rangeli forms in Trypanosoma cruzi-infected patients sera [PDF]

, 2008
Background American Trypanosomiasis or Chagas disease is caused by Trypanosoma cruzi which currently infects approximately 16 million people in the Americas causing high morbidity and mortality.
de Moraes, Milene H., Egera, Iriane, Girardia, Fabiana P., Grisard, Edmundo C., Guarneria, Alessandra A., Rodriguesa, Juliana B., Steindel, Mario, Tyler, Kevin M.   +7 more
core   +3 more sources

Protective immunity against Trypanosoma cruzi [PDF]

, 2009
Upon infection, Trypanosoma cruzi triggers a strong immune response that has both protective and pathological consequences. In this work, several important questions regarding protective immunity are reviewed.
Basombrío, Miguel Ángel Manuel, Padilla, Ángel Marcelo, Parodi Ramoneda, Cecilia María   +2 more
core   +1 more source

High Local Diversity of Trypanosoma in a Common Bat Species, and Implications for the Biogeography and Taxonomy of the T. cruzi Clade

PLoS ONE, 2014
The Trypanosoma cruzi clade is a group of parasites that comprises T. cruzi sensu lato and its closest relatives. Although several species have been confirmed phylogenetically to belong to this clade, it is uncertain how many more species can be expected
Veronika M. Cottontail, E. Kalko, Iain Cottontail, N. Wellinghausen, M. Tschapka, S. Perkins, C. Miguel Pinto   +6 more
semanticscholar   +1 more source

The promise of T. cruzi genomics [PDF]

Nature, 2010
The publishing of the first Trypanosoma cruzi genome sequence was hailed as “a huge intellectual triumph”, but what has it delivered?
openaire   +3 more sources