Results 31 to 40 of about 69,236 (249)
Parasites & Vectors, 2022 Background Components of the antioxidant defense system in Trypanosoma cruzi are potential targets for new drug development. Superoxide dismutases (SODs) constitute key components of antioxidant defense systems, removing excess superoxide anions by ...
Jéssica Hickson +10 more
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Xanthine Analogs Suppress Trypanosoma cruzi Infection In Vitro Using PDEs as Targets
Microbiology Research, 2022 Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, has infected 6 million people, putting 70 million people at risk worldwide. Presently, very limited drugs are available, and these have severe side effects.
Amita R. Banga +9 more
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Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? [PDF]
, 2016 Indexación: Web of Science.Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T.
A Colombo +42 more
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Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection. [PDF]
PLoS Pathogens, 2016 Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite, Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global insights into the T.
Yuan Li +11 more
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A neuraminidase from Trypanosoma cruzi removes sialic acid from the surface of mammalian myocardial and endothelial cells [PDF]
, 2014 Trypanosoma cruzi causes Chagasic heart disease, a major public health problem in Latin America. The mechanism of interaction of this protozooan parasite with host cells is poorly understood.
Alroy, J, Libby, Peter, Pereira, M E
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Revista da Sociedade Brasileira de Medicina Tropical, 1991 The unlabelled antibody peroxidase-antiperoxidase method was used to study the immunocytochemical properties of Leishmania and Trypanosoma cruzi amastigotes in situ after tissues had been submitted to different fixation procedures. Antisera were obtained
A.J.A. Barbosa +5 more
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Genome size, karyotype polymorphism and chromosomal evolution in Trypanosoma cruzi. [PDF]
PLoS ONE, 2011 BackgroundThe Trypanosoma cruzi genome was sequenced from a hybrid strain (CL Brener). However, high allelic variation and the repetitive nature of the genome have prevented the complete linear sequence of chromosomes being determined.
Renata T Souza +9 more
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Habitat Management to Reduce Human Exposure to Trypanosoma cruzi and Western Conenose Bugs (Triatoma protracta). [PDF]
, 2016 Chagas disease, which manifests as cardiomyopathy and severe gastrointestinal dysfunction, is caused by Trypanosoma cruzi, a vector-borne parasite. In California, the vector Triatoma protracta frequently colonizes woodrat (Neotoma spp.) lodges, but may ...
Conrad, Patricia +4 more
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Journal of Neuroinflammation, 2017 Background In conditions of immunosuppression, the central nervous sty 5ystem (CNS) is the main target tissue for the reactivation of infection by Trypanosoma cruzi, the causative agent of Chagas disease. In experimental T.
Andrea Alice Silva +7 more
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Proximity-Dependent Biotinylation and Identification of Flagellar Proteins in Trypanosoma cruzi
mSphere, 2023 The flagellated kinetoplastid protozoan and causative agent of human Chagas disease, Trypanosoma cruzi, inhabits both invertebrate and mammalian hosts over the course of its complex life cycle. In these disparate environments, T.
Madalyn M. Won +2 more
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