Results 31 to 40 of about 12,032,280 (304)
Plasminogen interaction with Trypanosoma cruzi [PDF]
Memórias do Instituto Oswaldo Cruz, 2004 The ability of Trypanosoma cruzi to interact with plasminogen, the zimogenic form of the blood serin protease plasmin, was examined. Immunohistochemistry studies revealed that both forms, epimastigotes and metacyclic trypomastigotes, were able to fix plasminogen in a lysine dependant manner.
Laura Almeida +4 more
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Trypanosoma cruzi: circulating antigens [PDF]
Memórias do Instituto Oswaldo Cruz, 1981 Circulating antigens were detected in sera of mice experimentally infected with a high close of Trypanosoma cruzi by reaction with sera from chronically infected mice. The immunodiffusion reaction between homologous acute and chronic sera produced four precipitation lines.
Bongertz, V. +2 more
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Gap junction reduction in cardiomyocytes following transforming growth factor- beta treatment and Trypanosoma cruzi infection [PDF]
, 2009 Gap junction connexin-43 (Cx43) molecules are responsible for electrical impulse conduction in the heart and are affected by transforming growth factor-beta (TGF-beta).
Becker, D +6 more
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Clathrin expression in Trypanosoma cruzi [PDF]
BMC Cell Biology, 2014 Clathrin-mediated vesicular trafficking, the mechanism by which proteins and lipids are transported between membrane-bound organelles, accounts for a large proportion of import from the plasma membrane (endocytosis) and transport from the trans-Golgi network towards the endosomal system.
Ligia Cristina Kalb +6 more
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Xanthine Analogs Suppress Trypanosoma cruzi Infection In Vitro Using PDEs as Targets
Microbiology Research, 2022 Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, has infected 6 million people, putting 70 million people at risk worldwide. Presently, very limited drugs are available, and these have severe side effects.
Amita R. Banga +9 more
doaj +1 more source
Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? [PDF]
, 2016 Indexación: Web of Science.Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T.
A Colombo +42 more
core +1 more source
Profiling the Trypanosoma cruzi Phosphoproteome [PDF]
PLoS ONE, 2011 Protein phosphorylation is a reversible post-translational modification essential for the regulation of several signal transduction pathways and biological processes in the living cell. Therefore, the identification of protein phosphorylation sites is crucial to understand cell signaling control at the molecular level.
Marco Aurélio Krieger +8 more
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Revista do Instituto de Medicina Tropical de São Paulo, 2007 Trypanosoma rangeli is non pathogenic for humans but of important medical and epidemiological interest because it shares vertebrate hosts, insect vectors, reservoirs and geographic areas with T. cruzi, the etiological agent of Chagas disease.
Paula Ximena Pavia +4 more
doaj +1 more source
Parasites & Vectors, 2022 Background Components of the antioxidant defense system in Trypanosoma cruzi are potential targets for new drug development. Superoxide dismutases (SODs) constitute key components of antioxidant defense systems, removing excess superoxide anions by ...
Jéssica Hickson +10 more
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Proximity-Dependent Biotinylation and Identification of Flagellar Proteins in Trypanosoma cruzi
mSphere, 2023 The flagellated kinetoplastid protozoan and causative agent of human Chagas disease, Trypanosoma cruzi, inhabits both invertebrate and mammalian hosts over the course of its complex life cycle. In these disparate environments, T.
Madalyn M. Won +2 more
doaj +1 more source