Results 1 to 10 of about 3,899,518 (170)

In vitro maturation of human pluripotent stem cell-derived cardiomyocyte: A promising approach for cell therapy

Journal of Animal Reproduction and Biotechnology, 2022
Currently, there is no treatment to reverse or cure heart failure caused by ischemic heart disease and myocardial infarction despite the remarkable advances in modern medicine.
Yun-Gwi Park, Yeo-Jin Son, Sung-Hwan Moon, Soon-Jung Park   +3 more
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Novel microRNAs modulating ecto-5′-nucleotidase expression

Frontiers in Immunology, 2023
IntroductionThe expression of immune checkpoint molecules (ICMs) by cancer cells is known to counteract tumor-reactive immune responses, thereby promoting tumor immune escape.
Theresa Kordaß, Theresa Kordaß, Tsu-Yang Chao, Wolfram Osen, Stefan B. Eichmüller   +4 more
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Characterization and reduction of non-endocrine cells accompanying islet-like endocrine cells differentiated from human iPSC

Scientific Reports, 2022
The differentiation of pancreatic endocrine cells from human pluripotent stem cells has been thoroughly investigated for their application in cell therapy against diabetes.
Hideyuki Hiyoshi, Kensuke Sakuma, Noriko Tsubooka-Yamazoe, Shinya Asano, Taisuke Mochida, Junji Yamaura, Shuhei Konagaya, Ryo Fujii, Hirokazu Matsumoto, Ryo Ito, Taro Toyoda   +10 more
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Recent advances in edible coating of food products and its legislations: A review

Journal of Agriculture and Food Research, 2023
Food products are highly perishable in nature which undergoes quick quality deterioration. In this note, the kind of packaging decides the active preservation of food qualities.
Krishna Priya, Nirmal Thirunavookarasu, D.V. Chidanand   +2 more
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ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes

Nature Communications, 2021
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) suffer from limited maturation. Here the authors identify ERRγ agonist as a factor that enhances cardiac morphological, metabolic, contractile and electrical maturation of ...
Kenji Miki, Kohei Deguchi, Misato Nakanishi-Koakutsu, Antonio Lucena-Cacace, Shigeru Kondo, Yuya Fujiwara, Takeshi Hatani, Masako Sasaki, Yuki Naka, Chikako Okubo, Megumi Narita, Ikue Takei, Stephanie C. Napier, Tsukasa Sugo, Sachiko Imaichi, Taku Monjo, Tatsuya Ando, Norihisa Tamura, Kenichi Imahashi, Tomoyuki Nishimoto, Yoshinori Yoshida   +20 more
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A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

Nature Communications, 2021
T-cell immunotherapies, such as CAR-T immunotherapy, are being developed against a wide variety of diseases. Here the authors report the feeder-free, scalable differentiation of human induced pluripotent cells (iPSCs) to T-cells with T-cell receptor ...
Shoichi Iriguchi, Yutaka Yasui, Yohei Kawai, Suguru Arima, Mihoko Kunitomo, Takayuki Sato, Tatsuki Ueda, Atsutaka Minagawa, Yuta Mishima, Nariaki Yanagawa, Yuji Baba, Yasuyuki Miyake, Kazuhide Nakayama, Maiko Takiguchi, Tokuyuki Shinohara, Tetsuya Nakatsura, Masaki Yasukawa, Yoshiaki Kassai, Akira Hayashi, Shin Kaneko   +19 more
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Chronic Inflammation Links Cancer and Parkinson’s disease

Frontiers in Aging Neuroscience, 2016
An increasing number of genetic studies suggest that the pathogenesis of Parkinson’s disease (PD) and cancer share common genes, pathways, and mechanisms.
Zhiming eLi, Zhiming eLi, Zaozao eZheng, Zaozao eZheng, Jun eRuan, Jun eRuan, Zhi eLi, Zhi eLi, Chi-Meng eTzeng, Chi-Meng eTzeng, Chi-Meng eTzeng   +10 more
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Downregulation of HMGB1 in thymoma cells affects T cell differentiation

Central European Journal of Immunology, 2023
Introduction: Thymoma is the most common anterior mediastinal tumor and is closely associated with myasthenia gravis (MG). Our previous study showed that the expression of Th17 cells increased and the expression of Treg decreased in MG-associated thymoma
Jian Li, Zeyang Zhang, Yuan Chen, Yuanguo Wang, Yuxin Liu, Peng Zhang   +5 more
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T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development

Cell Reports, 2020
Summary: T cell factor 1 (Tcf1) promotes the central memory CD8+ T (TCM) cell differentiation and stemness in lymphoid tissues after systemic infections.
Jingxia Wu, Alaa Madi, Alessa Mieg, Agnes Hotz-Wagenblatt, Nina Weisshaar, Sicong Ma, Kerstin Mohr, Tilo Schlimbach, Marvin Hering, Helena Borgers, Guoliang Cui   +10 more
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Ex-vivo CS1-OKT3 dual specific bivalent antibody-armed effector T cells mediate cellular immunity against multiple myeloma

Scientific Reports, 2023
Bispecific T cell engaging antibodies (bsAbs) have emerged as novel and powerful therapeutic agents for redirecting T cells towards antigen-specific tumor killing.
Dennis Awuah, Lin Li, Lindsay Williams, Ryan Urak, Maciej Kujawski, Stephen J. Forman, John E. Shively, Xiuli Wang   +7 more
doaj   +1 more source