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Journal of Animal Reproduction and Biotechnology, 2022
Currently, there is no treatment to reverse or cure heart failure caused by ischemic heart disease and myocardial infarction despite the remarkable advances in modern medicine.
Yun-Gwi Park+3 more
doaj +1 more source
Currently, there is no treatment to reverse or cure heart failure caused by ischemic heart disease and myocardial infarction despite the remarkable advances in modern medicine.
Yun-Gwi Park+3 more
doaj +1 more source
Novel microRNAs modulating ecto-5′-nucleotidase expression
Frontiers in Immunology, 2023IntroductionThe expression of immune checkpoint molecules (ICMs) by cancer cells is known to counteract tumor-reactive immune responses, thereby promoting tumor immune escape.
Theresa Kordaß+4 more
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The role of antigen-competitive dynamics in regulating the immune response [PDF]
Bulletin of Mathematical Biology, 83(5): 40 (2021), 2021The clonal expansion of T cells during an infection is tightly regulated to ensure an appropriate immune response against invading pathogens. Although experiments have mapped the trajectory from expansion to contraction, the interplay between mechanisms that control this response are not fully understood.
arxiv +1 more source
Scientific Reports, 2022
The differentiation of pancreatic endocrine cells from human pluripotent stem cells has been thoroughly investigated for their application in cell therapy against diabetes.
Hideyuki Hiyoshi+10 more
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The differentiation of pancreatic endocrine cells from human pluripotent stem cells has been thoroughly investigated for their application in cell therapy against diabetes.
Hideyuki Hiyoshi+10 more
doaj +1 more source
ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes
Nature Communications, 2021Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) suffer from limited maturation. Here the authors identify ERRγ agonist as a factor that enhances cardiac morphological, metabolic, contractile and electrical maturation of ...
Kenji Miki+20 more
doaj +1 more source
Real-time stain-free classification of cancer cells and blood cells using interferometric phase microscopy and machine learning [PDF]
Cytometry A 99: 511-523, 2021, 2021We present a method for a real time visualization and automatic processing for detection and classification of untouched cancer cells in blood during stain free imaging flow cytometry using digital holographic microscopy and machine learning in throughput of 15 cells per second.
arxiv +1 more source
Nature Communications, 2021
T-cell immunotherapies, such as CAR-T immunotherapy, are being developed against a wide variety of diseases. Here the authors report the feeder-free, scalable differentiation of human induced pluripotent cells (iPSCs) to T-cells with T-cell receptor ...
Shoichi Iriguchi+19 more
doaj +1 more source
T-cell immunotherapies, such as CAR-T immunotherapy, are being developed against a wide variety of diseases. Here the authors report the feeder-free, scalable differentiation of human induced pluripotent cells (iPSCs) to T-cells with T-cell receptor ...
Shoichi Iriguchi+19 more
doaj +1 more source
Survey of Ophthalmology, 2007
A 64-year-old woman presented with bilateral optic nerve swelling, vitreous cells, and cerebrospinal fluid monocytic pleocytosis. A chest radiograph and computed tomography demonstrated a lesion in the left lung, which histologically was confirmed to be a small-cell lung carcinoma.
Departments of Ophthalmology and Medicine (Division of Neurology), Duke University Eye Center and Duke University Medical Center, Durham, North Carolina ( host institution )+4 more
openaire +4 more sources
A 64-year-old woman presented with bilateral optic nerve swelling, vitreous cells, and cerebrospinal fluid monocytic pleocytosis. A chest radiograph and computed tomography demonstrated a lesion in the left lung, which histologically was confirmed to be a small-cell lung carcinoma.
Departments of Ophthalmology and Medicine (Division of Neurology), Duke University Eye Center and Duke University Medical Center, Durham, North Carolina ( host institution )+4 more
openaire +4 more sources
Cells, Stem Cells, and Cancer Stem Cells [PDF]
Seminars in Reproductive Medicine, 2013The stem cell field owes a great deal to the previous work conducted by embryologists and researchers devoted to reproductive medicine. The time is coming when this emerging field will pay off in the reproductive sciences by offering new avenues of understanding gametogenesis and early embryonic development.
Carlos Simón+1 more
openaire +4 more sources
Axicabtagene Ciloleucel CAR T‐Cell Therapy in Refractory Large B‐Cell Lymphoma
New England Journal of Medicine, 2017Background In a phase 1 trial, axicabtagene ciloleucel (axi‐cel), an autologous anti‐CD19 chimeric antigen receptor (CAR) T‐cell therapy, showed efficacy in patients with refractory large B‐cell lymphoma after the failure of conventional therapy. Methods
S. Neelapu+39 more
semanticscholar +1 more source