Results 11 to 20 of about 8,006,579 (361)
Human T cell glycosylation and implications on immune therapy for cancer [PDF]
, 2020 Glycosylation is an important post-translational modification, giving rise to a diverse and abundant repertoire of glycans on the cell surface, collectively known as the glycome.
Callewaert, Nico +3 more
core +1 more source
Survey of Ophthalmology, 2007 A 64-year-old woman presented with bilateral optic nerve swelling, vitreous cells, and cerebrospinal fluid monocytic pleocytosis. A chest radiograph and computed tomography demonstrated a lesion in the left lung, which histologically was confirmed to be a small-cell lung carcinoma.
Departments of Ophthalmology and Medicine (Division of Neurology), Duke University Eye Center and Duke University Medical Center, Durham, North Carolina ( host institution ) +4 more
openaire +4 more sources
Cells, Stem Cells, and Cancer Stem Cells [PDF]
Seminars in Reproductive Medicine, 2013 The stem cell field owes a great deal to the previous work conducted by embryologists and researchers devoted to reproductive medicine. The time is coming when this emerging field will pay off in the reproductive sciences by offering new avenues of understanding gametogenesis and early embryonic development.
Carlos Simón +1 more
openaire +4 more sources
Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming [PDF]
, 2015 Foxp3(+) regulatory T cells (Tregs) maintain immune homoeostasis through mechanisms that remain incompletely defined. Here by two-photon (2P) imaging, we examine the cellular dynamics of endogenous Tregs.
Cahalan, Michael D +9 more
core +3 more sources
Regulation of cell cycle progression by cell–cell and cell–matrix forces [PDF]
Nature Cell Biology, 2018 It has long been proposed that the cell cycle is regulated by physical forces at the cell-cell and cell-extracellular matrix (ECM) interfaces1-12. However, the evolution of these forces during the cycle has never been measured in a tissue, and whether this evolution affects cell cycle progression is unknown.
Marina Uroz +7 more
openaire +4 more sources
Chronic Inflammation Links Cancer and Parkinson’s disease
Frontiers in Aging Neuroscience, 2016 An increasing number of genetic studies suggest that the pathogenesis of Parkinson’s disease (PD) and cancer share common genes, pathways, and mechanisms.
Zhiming eLi +10 more
doaj +1 more source
Transcript-indexed ATAC-seq for precision immune profiling. [PDF]
, 2018 T cells create vast amounts of diversity in the genes that encode their T cell receptors (TCRs), which enables individual clones to recognize specific peptide-major histocompatibility complex (MHC) ligands. Here we combined sequencing of the TCR-encoding
Buenrostro, Jason D +21 more
core +1 more source
Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression. [PDF]
, 2007 The impact of regulatory T cells (T reg cells) on the course of HIV and SIV disease is unknown. T reg cells could suppress protective antiviral responses and accelerate disease progression.
Abel, Kristina +2 more
core +2 more sources
Mathematical deconvolution of CAR T-cell proliferation and exhaustion from real-time killing assay data. [PDF]
, 2020 Chimeric antigen receptor (CAR) T-cell therapy has shown promise in the treatment of haematological cancers and is currently being investigated for solid tumours, including high-grade glioma brain tumours.
Abler, Daniel +13 more
core +2 more sources
FEBS Letters, 2007 Cell–cell fusion is a highly regulated and dramatic cellular event that is required for development and homeostasis. Fusion may also play a role in the development of cancer and in tissue repair by stem cells. While virus–cell fusion and the fusion of intracellular membranes have been the subject of intense investigation during the past decade, cell ...
Elizabeth H. Chen +3 more
openaire +3 more sources